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Robarts researcher identifies protein which regulates cell suicide

When cells experience DNA damage, they'll try to repair it. But if that fails, the damaged cells are supposed to self-destruct, a process called apoptosis. A cancer researcher at Robarts Research Institute at The University of Western Ontario has identified a protein that regulates apoptosis, a new discovery which has implications for both the diagnosis and treatment of cancer. Caroline Schild-Poulter's findings are now published online in the journal Molecular Cancer Research.

10 Dec 2009

New protein discovery may serve as potential marker of drug addiction

Scientists are adding additional brush strokes to the revolutionary new image now emerging for star-shaped cells called astrocytes in the brain and spinal cord. Their report, which suggests a key role for astrocytes in morphine's ability to relieve pain and cause addiction, appears online in ACS' Journal of Proteome Research, a monthly publication.

10 Dec 2009

Updated NCCN Guidelines include maintenance therapy for patients with metastatic disease

The National Comprehensive Cancer Network (NCCN) recently updated the NCCN Guidelines for Non-Small Cell Lung Cancer (NSCLC) to incorporate a new section about maintenance therapy, a number of new indications for specific therapies for advanced NSCLC, and the recently revised staging system for lung cancer.

10 Dec 2009

New study suggests mercury-based dental fillings may be less toxic than previously thought

A new study on the surface chemistry of silver-colored, mercury-based dental fillings suggests that the surface forms of mercury may be less toxic than previously thought. It appears online in ACS' journal Chemical Research in Toxicology.

10 Dec 2009

JMC receives NIH grant to establish center of excellence for autoimmune diseases

The Department of Neurology at Jefferson Medical College (JMC) of Thomas Jefferson University has been awarded a multi-million dollar grant from the National Institutes of Health (NIH) for the creation of a center of excellence to study autoimmune diseases from basic science research to its translation into clinical applications.

10 Dec 2009

New research suggests cancer drug may also help patients suffering from asthma

Scientists at the University of Edinburgh found that the drug - R-Roscovitine - helps to kill certain immune cells which can exacerbate symptoms associated with asthma.

10 Dec 2009

Preliminary study shows 'mini' stem cell transplantation may safely reverse severe sickle cell disease

Results of a preliminary study by scientists at the National Institutes of Health and Johns Hopkins show that "mini" stem cell transplantation may safely reverse severe sickle cell disease in adults.

9 Dec 2009

RegeneRx Biopharmaceuticals completes Phase I trial evaluating systemic administration of RGN-352

REGENERX BIOPHARMACEUTICALS, INC. announced today that it has completed and analyzed the safety data from its double-blind, placebo controlled Phase I clinical trial evaluating the systemic administration of RGN-352. The trial included testing of a single escalating intravenous dose of the drug candidate on forty healthy volunteers in Phase IA and, subsequently, over a fourteen-day treatment period on forty volunteers in Phase IB.

9 Dec 2009

CORD:USE Cord Blood Bank awarded contract to supply blood units for the NCBI

CORD:USE Cord Blood Bank is proud to announce that the Health Resources and Services Administration (HRSA) of the U.S. Department of Health and Human Services has awarded CORD:USE Cord Blood Bank a three-year, multi-million dollar contract to expand the supply of cord blood units for the National Cord Blood Inventory (NCBI).

9 Dec 2009

Newly created line of skin care products based on ISCO’s proprietary Parthenogenic Stem Cells

Lifeline Skin Care, Inc, a wholly owned subsidiary of International Stem Cell Corporation, announced today that it has retained the services of a highly experienced expert in the skin care industry, Raulee Marcus, to help design a marketing program for its newly created line of skin care products based on ISCO’s proprietary Parthenogenic Stem Cells.

9 Dec 2009

Protalix Biotherapeutics completes NDA submission for taliglucerase alfa

Protalix Biotherapeutics, Inc. today announced the completion of its New Drug Application (NDA) submission with the U.S. Food and Drug Administration (FDA) for taliglucerase alfa, a plant-cell expressed form of glucocerebrosidase (GCD) for the potential treatment of Gaucher’s disease.

9 Dec 2009

Preliminary data from Phase 2 clinical trial of ZFP Therapeutic program presented

Sangamo BioSciences, Inc. announced today the presentation of preliminary data from the Phase 2 clinical trial of its ZFP Therapeutic(TM) program to develop SB-509 as a treatment for amyotrophic lateral sclerosis (ALS) at a Work in Progress session at the 20th International Symposium on ALS/MND held in Berlin, Germany.

9 Dec 2009

VERTICAL Phase II trial results for NHL released

The Takeda Oncology Company today reported data from a clinical trial evaluating a VELCADE based combination for patients with relapsed/refractory non-Hodgkin’s lymphoma (NHL).

9 Dec 2009

LCA-Vision to provide free corrective vision surgery to U.S. military veterans

LCA-Vision Inc. (Nasdaq: LCAV), a leading provider of laser vision correction services under the LasikPlus® brand, announced today that it has joined forces with the Wounded Warrior Project to provide free LasikPlus® corrective vision surgery to U.S. military veterans and their spouses/caregivers across the nation.

9 Dec 2009

AHS annual meeting focuses on myeloma, says IMF

The International Myeloma Foundation (IMF)—supporting research and providing education, advocacy and support for myeloma patients, families, researchers and physicians— says a large number of abstracts – nearly a quarter of the presentations submitted this year to the annual meeting of the American Society of Hematology (ASH) were for myeloma, with one being presented at the prestigious plenary session.

9 Dec 2009

Universities purchase Elsevier's SciVal Spotlight tool to enhance research strategies

Elsevier, a world-leading publisher of scientific, technical and medical information products and services, today announced that several universities have purchased its new SciVal Spotlight tool.

9 Dec 2009

New drug designed to stop cancer from spreading by preventing mitosis

TGen Clinical Research Services at Scottsdale Healthcare (TCRS) is the world's first clinical trials site for a new drug designed to halt cancer cell division.

9 Dec 2009

Human blood stem cells can be engineered to kill HIV and other chronic viral diseases

Researchers from the UCLA AIDS Institute and colleagues have for the first time demonstrated that human blood stem cells can be engineered into cells that can target and kill HIV-infected cells - a process that potentially could be used against a range of chronic viral diseases.

9 Dec 2009

Recruitment complete in Oxagen's OC000459 IIb clinical trial for asthma

Oxagen Limited, a drug discovery and development company specializing in inflammation, today announced that the recruitment for its double blind, randomised, placebo controlled Phase IIb clinical trial in asthma with OC000459, its lead oral CRTH2 (DP2) antagonist, has now been completed.

9 Dec 2009

CSC's stem cell-derived motor neuron product for SMA receives FDA orphan drug designation

California Stem Cell, Inc. (CSC) and Families of Spinal Muscular Atrophy (FSMA) announced today that the FDA has granted orphan drug designation to MOTORGRAFT™, a stem cell-derived motor neuron product, for the treatment of Spinal Muscular Atrophy (SMA).

9 Dec 2009

Cell News and Research

Robarts researcher identifies protein which regulates cell suicide

New protein discovery may serve as potential marker of drug addiction

Updated NCCN Guidelines include maintenance therapy for patients with metastatic disease

New study suggests mercury-based dental fillings may be less toxic than previously thought

JMC receives NIH grant to establish center of excellence for autoimmune diseases

New research suggests cancer drug may also help patients suffering from asthma

Preliminary study shows 'mini' stem cell transplantation may safely reverse severe sickle cell disease

RegeneRx Biopharmaceuticals completes Phase I trial evaluating systemic administration of RGN-352

CORD:USE Cord Blood Bank awarded contract to supply blood units for the NCBI

Newly created line of skin care products based on ISCO’s proprietary Parthenogenic Stem Cells

Protalix Biotherapeutics completes NDA submission for taliglucerase alfa

Preliminary data from Phase 2 clinical trial of ZFP Therapeutic program presented

VERTICAL Phase II trial results for NHL released

LCA-Vision to provide free corrective vision surgery to U.S. military veterans

AHS annual meeting focuses on myeloma, says IMF

Universities purchase Elsevier's SciVal Spotlight tool to enhance research strategies

New drug designed to stop cancer from spreading by preventing mitosis

Human blood stem cells can be engineered to kill HIV and other chronic viral diseases

Recruitment complete in Oxagen's OC000459 IIb clinical trial for asthma

CSC's stem cell-derived motor neuron product for SMA receives FDA orphan drug designation

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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