Cell News and Research

RSS

DNA free radical damage research

Certain prostate cancer cell lines are unable to repair DNA damage caused by "free radicals," according to scientists at the National Institute of Standards and Technology (NIST) and National Institutes of Health (NIH). This type of damage has been implicated before in the development of prostate cancer, but the new research provides the first solid evidence that the normal repair process is altered in prostate cancer cells, possibly leading to a cascade of events that culminate in further DNA damage and cellular dysfunction.

9 Apr 2004

Cell research to eventually develop new treatments for cancer and disorders such as Parkinson’s and Huntington’s disease

Medical Research Council (MRC) scientists have made an important advance in understanding the biological processes involved when cells die. The work may help scientists to eventually develop new treatments for cancer and disorders such as Parkinson’s and Huntington’s disease.

8 Apr 2004

New process to extract proteins from membranes by using chemicals

Proteins are complex compounds that are essential for the growth and repair of tissue. While scientists understand much about the structure and stability of water-soluble proteins that ‘float’ around in humans, they know very little about the shape and stability of proteins that are embedded, or folded, into the lipid membrane of cells. Such membrane proteins make up about 30 percent of all proteins in the body.

8 Apr 2004

University of Florida researchers have used a common gel to successfully deliver gene therapy to the diaphragm

The technique, described in the current issue of Molecular Therapy, could eventually lead to a method to correct genetic conditions in humans that cause diaphragm weakness and respiratory failure -- a leading cause of death in tens of thousands of patients with forms of muscular dystrophy, including Pompe’s disease. Thousands of Americans with muscle-weakening diseases are placed on ventilators each year, according to the Muscular Dystrophy Association.

7 Apr 2004

Genetic trick makes gene therapy vectors more versatile

A genetic trick used by viruses to replicate themselves has been adapted for laboratory use to build complex protein structures required by immune system cells, according to investigators at St. Jude Children’s Research Hospital.

7 Apr 2004

Molecular analyses of leukemia patients suggest strategies for better treatments

The cure rate for pediatric acute lymphoblastic leukemia (ALL) might continue to rise with improved use of conventional therapies. But even more effective and less toxic therapies based on genetic and pharmacogenetic studies might one day push the success rate close to 100 percent, according to an article published by investigators at St. Jude Children’s Research Hospital in the April 8 issue of the New England Journal of Medicine.

7 Apr 2004

Completion of the sequencing of human chromosome 19

The United States Department of Energy (DOE) Joint Genome Institute (JGI) and Stanford University report today the completion of the sequencing of human chromosome 19, the most gene-rich of all the human chromosomes. This achievement is described in the April 1, 2004 edition of the journal Nature.

7 Apr 2004

New method to induce embryonic stem cells to develop into bone marrow and blood cells

Researchers at Northwestern University have devised a method to induce embryonic stem cells to develop into bone marrow and blood cells. Injecting the stem cells into the bone marrow cavity of mice whose bone marrow cells had been depleted restored production of blood cells, including cells of the immune system, which normally are created in the bone marrow.

6 Apr 2004

Scientists studying vaccinia virus, a relative of smallpox, have determined that a gene necessary for virus replication also has a key role in turning off inflammation

Scientists at the University of Illinois at Urbana-Champaign studying vaccinia virus, a close relative of smallpox, have determined that a gene necessary for virus replication also has a key role in turning off inflammation, a crucial anti-viral immune response of host cells.

6 Apr 2004

Fluorescent molecule used to examine real time chemical reactions that result in smooth-muscle contraction

Smooth muscle, found in the walls of blood vessels and in internal organs such as lungs, stomach and the bladder, contracts as the end result of a series of chemical reactions. In a new study, UT Southwestern researchers report that one set of chemical reactions resulting in the contraction of the smooth-muscle cells is augmented by a second chemical pathway that kicks in when the first pathway is limited.

5 Apr 2004

The National Cancer Institute has awarded USC scientists $3.5 million for a study of the enzyme that faithfully copies our genetic information

The National Cancer Institute has awarded USC scientists $3.5 million for a study of the enzyme that faithfully copies our genetic information, enabling it to pass from one generation to the next. The grant will fund structural, biochemical and computer studies designed to reveal how the enzyme, DNA polymerase, makes so few mistakes.

5 Apr 2004

New device filters blood supplies on-site reducing the possible transmission of Creutzfeldt-Jakob disease

ProMetic Life Sciences Inc. has announced today that its joint venture with the American Red Cross, Pathogen Removal and Diagnostic Technology Inc. ("PRDT"), has confirmed that treatment of TSE spiked red blood cell concentrate with its Prion Reduction Device results in a significant decrease in associated infectivity.

5 Apr 2004

Mathematicians Predict Patterns in Fingerprints

Patterns in nature can be seen every day, yet in many cases, little is understood about how and why they form. Now University of Arizona mathematicians have found a way to predict natural patterns, including fingerprints and the spirals seen in cacti.

4 Apr 2004

New software promises to speed drug development

Researchers at Rensselaer Polytechnic Institute today announced the release of a software program capable of quickly identifying molecules that show promise for future medicines. The software program enables drug makers to comb through enormous databases of potential molecules and identify the ones that have sound medicinal properties.

3 Apr 2004

New center enables genetic treatments and advances

A new state-of-the-art research facility dedicated to helping produce modified cells for treatment of cancer and other diseases recently opened at the Siteman Cancer Center.

1 Apr 2004

Compounds that may stop replication of T-cell leukemia virus

Researchers are analyzing several compounds that may inhibit the enzyme that is essential for the reproduction of the Human T-cell Leukemia Virus Type 1 (HTLV-I), which has infected 15 to 20 million people worldwide. The virus causes the fatal adult T-cell leukemia in up to 10 percent of those infected.

1 Apr 2004

Lab discovers way to keep short-lived catalysts active for longer than five months

Enzymes, the workhorses of chemical reactions in cells, lead short and brutal lives. They cleave and assemble proteins and metabolize compounds for a few hours, and then they are spent. This sad fact of nature has limited the possibilities of harnessing enzymes as catalytic tools outside the cell, in uses that range from biosensing to toxic waste cleanup.

1 Apr 2004

Scientists have discovered that a non-genetic molecular process can effect cell behaviour

Genetic mutations, sudden, random and usually harmful changes to the structure of a gene, are only one factor that determines the ultimate fate of a cell. Chicago scientists have discovered that a non-genetic molecular process also can play a role, and that experimenters can influence this process in bacteria, they report in the April 1 issue of the journal Nature.

1 Apr 2004

T-cells in lupus patients avoid apoptosis and are stimulated to produce antibodies against the patients own DNA

Researchers studying autoimmune diseases have found a molecular mechanism that explains how T-cells in lupus patients avoid apoptosis and are stimulated to produce antibodies against the patients own DNA.

1 Apr 2004

Gene-rich human Chromosome 19 sequence completed

31 Mar 2004

Cell News and Research

DNA free radical damage research

Cell research to eventually develop new treatments for cancer and disorders such as Parkinson’s and Huntington’s disease

New process to extract proteins from membranes by using chemicals

University of Florida researchers have used a common gel to successfully deliver gene therapy to the diaphragm

Genetic trick makes gene therapy vectors more versatile

Molecular analyses of leukemia patients suggest strategies for better treatments

Completion of the sequencing of human chromosome 19

New method to induce embryonic stem cells to develop into bone marrow and blood cells

Scientists studying vaccinia virus, a relative of smallpox, have determined that a gene necessary for virus replication also has a key role in turning off inflammation

Fluorescent molecule used to examine real time chemical reactions that result in smooth-muscle contraction

The National Cancer Institute has awarded USC scientists $3.5 million for a study of the enzyme that faithfully copies our genetic information

New device filters blood supplies on-site reducing the possible transmission of Creutzfeldt-Jakob disease

Mathematicians Predict Patterns in Fingerprints

New software promises to speed drug development

New center enables genetic treatments and advances

Compounds that may stop replication of T-cell leukemia virus

Lab discovers way to keep short-lived catalysts active for longer than five months

Scientists have discovered that a non-genetic molecular process can effect cell behaviour

T-cells in lupus patients avoid apoptosis and are stimulated to produce antibodies against the patients own DNA

Gene-rich human Chromosome 19 sequence completed

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest Life Science News