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New spectroscopic approach investigates difficult-to-observe protein structures

Combining research-oriented teaching and interdisciplinary collaboration pays off: Researchers at the University of Konstanz develop a novel spectroscopic approach to investigate hitherto difficult-to-observe protein structures.

19 Jun 2019

Targeted breast cancer therapy shows 'encouraging' results

Researchers have developed a targeted therapy that may significantly increase the survival of pre-menopausal women with advanced breast cancer

3 Jun 2019

Targeted therapy plus hormone therapy improves survival in premenopausal patients with advanced HR+ breast cancer

Adding the targeted therapy ribociclib to hormone therapy significantly improved overall survival (OS) in premenopausal patients with advanced hormone receptor-positive (HR+) breast cancer, according to results of the MONALEESA-7 Phase III clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

3 Jun 2019

Viral study reveals new way to prevent kidney damage following organ transplant

While studying one of the smallest DNA viruses known, Sunnie Thompson, Ph.D., may have found a new way to help prevent kidney damage following organ transplant.

30 May 2019

Researchers develop new artificial intelligence tools to find cell’s true identity

Scientists have long sorted cells into different varieties based on their appearance under a microscope or, for differences that are more visually subtle, based on the behavior of a handful of genes.

From Johns Hopkins Medicine 29 May 2019

Yeast species thrives, despite losing DNA repair genes years ago

Researchers have discovered an ancient species of budding yeast that has lost dozens of DNA repair genes, without any adverse effects.

22 May 2019

Small molecule drug could be an effective strategy to treat glioblastoma

A team of researchers have published in the International Journal of Oncology that RITA, a drug able to reactivate the oncosuppressor function of p53, could be an effective strategy to treat glioblastoma.

21 May 2019

Honey from strawberry trees stops cell proliferation in colon cancer lines

Spanish and Italian researchers have proven that when honey from strawberry trees, a product typical of Mediterranean areas, is added to colon cancer cells grown in the laboratory, cell proliferation is stopped.

21 May 2019

Jefferson researcher discovers a population of bone cells that subdues cancer

In breast cancer, there are cases of women and men whose cancer returns in their bones 20-30 years after they were treated for their primary disease and thought they were cancer-free.

13 May 2019

International team studies potential cancer suppression mechanisms in cetaceans

Scientists know that age and weight are risk factors in the development of cancer. That should mean that whales, which include some of the largest and longest-lived animals on Earth, have an outsized risk of developing cancer.

13 May 2019

Inhibition of ribosome biogenesis as new treatment strategy for advanced cancers

Nearly ninety per cent of all cancer patient deaths are due to metastasis. A study from Uppsala University shows that a process that allows the cells to metastasize is aided by the synthesis of new ribosomes, the cell components in which proteins are produced.

8 May 2019

Study finding promises new perspectives for treatment of Type 2 endometrial cancer

Brazilian scientists identify the predominant presence of a truncated variant of the p53 protein in amyloid aggregates in endometrial cancer cells. Such structures are related to the progression of this tumor.

3 May 2019

Phasefocus to launch new cell imaging system with smart incubation technology

Phasefocus has secured additional investment as it prepares to launch the newest version of its flagship live cell imaging and analysis system, Livecyte™.

From Phase Focus Limited 19 Apr 2019

Biophysicists visualize atomic-level dynamics of largest protein-degrading machine

Protein dynamics are essential for their functions. Protein nanomachines made of multiple protein molecules are highly dynamics during their actions on their functional targets, sometime called substrates.

26 Feb 2019

Protein CDK6 appears to be key factor in influencing development of MPN

MPNs are a group of rare, malignant diseases of the bone marrow involving the production of an excess of red blood cells, white blood cells and/or platelets.

6 Feb 2019

Research using fission yeast reveals anticancer mechanism

Much like shoelaces or dangly necklaces, DNA strands can tangle up in unruly knots. Specialized enzymes keep DNA organized when cells divide, so the cells split smoothly and don't get stuck. But in tumor cells, this failsafe allows cancer to spread.

5 Feb 2019

Researchers find 'origin' of cancer spread

The discovery of the cell, which they are calling 'the cell of origin' sheds new light on what fuels cancer growth and how to potentially stop it.

4 Feb 2019

Researchers identify new therapeutic targets for kidney fibrosis

Chronic kidney disease is a global health concern, affecting about 10 percent of the world's population--and increasing in prevalence. A final, common pathway in chronic kidney disease is fibrosis.

29 Jan 2019

Nine early career scientists named 2019 recipients of the Damon Runyon-Rachleff Innovation Award

The Damon Runyon Cancer Research Foundation announced that nine scientists with novel approaches to fighting cancer have been named 2019 recipients of the Damon Runyon-Rachleff Innovation Award.

24 Jan 2019