Cell Death News and Research

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New targeted therapy zolbetuximab extends survival for patients with advanced gastric cancer

An international phase 3 clinical trial, done in participation with Weill Cornell Medicine and NewYork-Presbyterian, found that a new targeted treatment called zolbetuximab, given in combination with a standard chemotherapy, extended survival for patients with advanced gastric or gastroesophageal junction cancer that overexpressed a specific biomarker.

23 Aug 2023

Study explores the role of N6-methyladensoine methylation and COVID-19

A recent study summarized the recent advances in the role of N6-methyladenosine (m6A) methylation in COVID-19.

23 Aug 2023

New prognostic risk signature for kidney renal clear cell carcinoma identified

Announcing a new publication for Acta Materia Medica journal. Cuproptosis is a newly identified specific form of programmed cell death.

22 Aug 2023

The outcome of invasive S. pyogenes infection is regulated by an interplay between human STING genotype and bacterial NADase activity

The interplay between human STING genotype and bacterial NADase activity.

22 Aug 2023

Proxalutamide shows promise as potential COVID-19 treatment

At the outset of the COVID pandemic, men appeared to suffer higher rates of severe illness and death, leading researchers to suspect a link between androgen receptors-;which bind to hormones like testosterone--and SARS-CoV-2 viral infection.

18 Aug 2023

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Researchers describe molecular signalling regulated by mTOR among memory and exhausted cytotoxic CD8+ T lymphocytes.

18 Aug 2023

Rutgers scientists discover first lipid vascular 'zip code' in the lungs

Researchers at Rutgers Cancer Institute of New Jersey and Rutgers New Jersey Medical School (NJMS), together with other collaborating groups, have discovered the first lipid vascular 'ZIP code' in the lungs.

16 Aug 2023

A computational model identifies metabolites associated with Parkinson's disease

Researchers identify significant metabolites involved in the development and progression of Parkinson’s disease.

15 Aug 2023

New mechanism discovered for brain repair after ischemic stroke

Patients often experience functional decline after an ischemic stroke, especially due to the brain's resistance to regenerate after damage.

10 Aug 2023

The role of estrogen in osteoarthritis and lower back pain

Researchers review existing evidence on the association between estrogen, osteoarthritis, and lower back pain.

10 Aug 2023

Exploring molecular mechanisms and genetic dysregulation in aging and age-associated diseases

Researchers review existing data on the molecular basis of senescence and neurodegeneration in age-related brain diseases.

10 Aug 2023

How conversion between different types of cell death contributes to disease

Researchers elucidate the role of cell death in the pathogenesis of different diseases.

10 Aug 2023

Dendritic cells found to kill CD47-deficient T cells

Researchers at Kobe University discovered an entirely new and unexpected mechanism by which the immune system can get rid of cells lacking molecules that identify them as part of the self in mice.

8 Aug 2023

Recent advances in the understanding of the role and mechanism of CCAR2 in cancer

Researchers described the dual role of cell cycle and apoptosis regulator 2 (CCAR2) in cancer progression as a tumor suppressor and promoter.

4 Aug 2023

Nutrition meets cancer therapy: How gut microbiome and diet impact immunotherapy success

Researchers investigated the complex relationship between gut bacteria, diet, and patient nutrition.

4 Aug 2023

Surprising new role for a key immune regulator revealed

A signaling protein known as STING is a critical player in the human immune system, detecting signs of danger within cells and then activating a variety of defense mechanisms.

3 Aug 2023

TTUHSC researcher receives $1.76 million grant to investigate new pancreatic cancer treatment

With a survival rate in the single digits, pancreatic ductal adenocarcinoma (PDAC) is highly lethal. In fact, by the time PDAC is clinically diagnosed, it is already considered incurable via surgery or other means in up to 90% of patients.

2 Aug 2023

Phase 1 clinical trial underway to test City of Hope-developed cancer treatment

Researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, today published a new study explaining how they took a protein once thought to be too challenging for targeted therapy, proliferating cell nuclear antigen (PCNA), and developed a targeted chemotherapy that appears to annihilate all solid tumors in preclinical research.

1 Aug 2023

The long-term effects of SARS-CoV-2 infection on T cell activation: autoimmune disorders and endothelial cell dysfunction

Authors explored the impact of SARS-CoV-2 on thymus (T) cell activation.

1 Aug 2023

How effective is physical activity in alleviating obesity-related inflammation in diabetes?

Scientists determine whether physical activity can be used as an effective intervention to mitigate obesity-related inflammation in diabetes.

1 Aug 2023

Cell Death News and Research

New targeted therapy zolbetuximab extends survival for patients with advanced gastric cancer

Study explores the role of N6-methyladensoine methylation and COVID-19

New prognostic risk signature for kidney renal clear cell carcinoma identified

The outcome of invasive S. pyogenes infection is regulated by an interplay between human STING genotype and bacterial NADase activity

Proxalutamide shows promise as potential COVID-19 treatment

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Rutgers scientists discover first lipid vascular 'zip code' in the lungs

A computational model identifies metabolites associated with Parkinson's disease

New mechanism discovered for brain repair after ischemic stroke

The role of estrogen in osteoarthritis and lower back pain

Exploring molecular mechanisms and genetic dysregulation in aging and age-associated diseases

How conversion between different types of cell death contributes to disease

Dendritic cells found to kill CD47-deficient T cells

Recent advances in the understanding of the role and mechanism of CCAR2 in cancer

Nutrition meets cancer therapy: How gut microbiome and diet impact immunotherapy success

Surprising new role for a key immune regulator revealed

TTUHSC researcher receives $1.76 million grant to investigate new pancreatic cancer treatment

Phase 1 clinical trial underway to test City of Hope-developed cancer treatment

The long-term effects of SARS-CoV-2 infection on T cell activation: autoimmune disorders and endothelial cell dysfunction

How effective is physical activity in alleviating obesity-related inflammation in diabetes?

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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