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UC Santa Barbara professor finds method for measuring cellular forces that shape tissues, organs

Like tiny construction workers, cells sculpt embryonic tissues and organs in 3D space. This task is complicated and requires constant communication between cells to coordinate their actions and generate the forces that will shape their environment into complex tissue morphologies.

10 Dec 2013

Research: Notch protein plays essential role in triggering T-cell development

The lab of Avinash Bhandoola, PhD, professor of Pathology and Laboratory Medicine, has studied the origins of T cells for many years. One protein called Notch, which has well-known roles in the development of multiple tissues, plays an essential role in triggering T-cell development.

25 Nov 2013

Philipp E. Scherer honored with 15th Naomi Berrie Award for Outstanding Research in Diabetes

Columbia University Medical Center has honored Philipp E. Scherer, PhD, with the 15th Naomi Berrie Award for Outstanding Research in Diabetes, for his work that helped usher in a new understanding of fat and its role in diabetes and other metabolic diseases. His discovery of adiponectin, a hormone produced by fat, helped transform the scientific concept of fat as an inert storage depot to one of it as an endocrine "organ" that exerts control over the brain, muscles, and other organs. The award, given annually by CUMC's Naomi Berrie Diabetes Center, is Columbia's top honor for excellence in diabetes research.

19 Nov 2013

Scientists describe interplay of four molecules that trigger, govern antibody production in immune cells

Australian scientists have described an exquisitely balanced interplay of four molecules that trigger and govern antibody production in immune cells. As well as being an important basic science discovery, it helps explain why people with mutations in any one of the associated genes cannot fight infection effectively, and develop rare and crippling immunodeficiency disorders.

18 Nov 2013

Gladstone-led study sheds light on critical molecular process

One of biology's most fundamental processes is something called transcription. It is just one step of many required to build proteins-and without it life would not exist. However, many aspects of transcription remain shrouded in mystery. But now, scientists at the Gladstone Institutes are shedding light on key aspects of transcription, and in so doing are coming even closer to understanding the importance of this process in the growth and development of cells-as well as what happens when this process goes awry.

8 Nov 2013

Life-saving bone marrow transplants may also cure peanut allergies

Not only can bone marrow transplants be life-saving for children with acute lymphocytic leukemia, they may also cure peanut allergies. According to research presented during the American College of Allergy, Asthma and Immunology's Annual Scientific Meeting, a 10-year-old boy no longer had a peanut allergy after undergoing a bone marrow transplant.

8 Nov 2013

Discovery could rev up body's immune response to infection, autoimmune diseases

UT Southwestern Medical Center researchers report that disrupting the light-dark cycle of mice increased their susceptibility to inflammatory disease, indicating that the production of a key immune cell is controlled by the body's circadian clock.

8 Nov 2013

Epigenetics may be useful target to stop the growth, spread and relapse of cancer

A review article by researchers at Boston University School of Medicine suggests that epigenetics may be a useful target to stop the growth, spread and relapse of cancer. The findings are published online in Volume 14 of the International Journal of Molecular Science.

31 Oct 2013

Diverse Neurological Disorders Appear To Share Tangled Metabolic Roots

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10 Oct 2013

Gene mutation offers clues to development of diverse neurological disorders

A research team, headed by Theodore Friedmann, MD, professor of pediatrics at the University of California, San Diego School of Medicine, says a gene mutation that causes a rare but devastating neurological disorder known as Lesch-Nyhan syndrome appears to offer clues to the developmental and neuronal defects found in other, diverse neurological disorders like Alzheimer's, Parkinson's and Huntington's diseases.

10 Oct 2013

Scientists discover critical regulator for directing pluripotent stem cells to make blood-forming stem cells

Stem cell scientists have moved one step closer to producing blood-forming stem cells in a Petri dish by identifying a key regulator controlling their formation in the early embryo, shows research published online today in Cell.

27 Sep 2013

Protein pair may be prognostic biomarker for identifying smoking-related lung cancers

Mayo Clinic researchers have shown that a specific protein pair may be a successful prognostic biomarker for identifying smoking-related lung cancers. The protein — ASCL1 — is associated with increased expression of the RET oncogene, a particular cancer-causing gene called RET. The findings appear in the online issue of the journal Oncogene.

20 Sep 2013

LA BioMed researchers to explore influence of maternal obesity, BPA in fetal development

While much of the obesity prevention efforts today focus on diet and exercise, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center researchers are going even further back in time to explore what happens during development in the womb that could lead to overeating and obesity later in life.

13 Sep 2013

Research may shed light on what causes people to suffer from life-threatening anxiety disorders

New research at Rutgers University may help shed light on how and why nervous system changes occur and what causes some people to suffer from life-threatening anxiety disorders while others are better able to cope.

20 Aug 2013

Interactions between sympathetic neurons and pancreatic cells have implications for organ development

The human body is a complicated system of blood vessels, nerves, organs, tissue and cells each with a specific job to do. When all are working together, it's a symphony of form and function as each instrument plays its intended roles.

17 Aug 2013

Research findings offer clues to the origin of retinal disorders later in life

Scientists are developing a clearer picture of how visual systems develop in mammals. The findings offer important clues to the origin of retinal disorders later in life.

9 Aug 2013

New stem cell discovery may help scientists replace damaged organs

Stem-cell researchers at UC San Francisco have found a key role for a protein called BMI1 that may help scientists direct the development of tissues to replace damaged organs in the human body.

22 Jul 2013

Montana scientist receives ICAAC Young Investigator Award for research on memory responses to infection

Joshua Obar, Ph.D., Department of Immunology and Infectious Diseases, Montana State University-Bozeman, has been honored with a 2013 ICAAC Young Investigator Award for his research on factors affecting the regulation of immunological memory responses to infection.

19 Jun 2013

Exposing tissue to low levels of BPA linked to greater incidence of prostate cancer

Exposing developing tissue to low levels of the plastic bisphenol A, commonly known as BPA, is linked to a greater incidence of prostate cancer in tissue grown from human prostate stem cells, a new study finds. The results were presented Monday, June 17, at The Endocrine Society's 95th Annual Meeting in San Francisco.

19 Jun 2013

New gene variant found in human and animal tissue offers a promising treatment for cancer

A novel gene variant found in human and animal tissue may be a promising treatment for cancer, including breast and brain cancer, according to scientists from the Icahn School of Medicine at Mount Sinai.

7 Jun 2013

Cell Development News and Research

UC Santa Barbara professor finds method for measuring cellular forces that shape tissues, organs

Research: Notch protein plays essential role in triggering T-cell development

Philipp E. Scherer honored with 15th Naomi Berrie Award for Outstanding Research in Diabetes

Scientists describe interplay of four molecules that trigger, govern antibody production in immune cells

Gladstone-led study sheds light on critical molecular process

Life-saving bone marrow transplants may also cure peanut allergies

Discovery could rev up body's immune response to infection, autoimmune diseases

Epigenetics may be useful target to stop the growth, spread and relapse of cancer

Diverse Neurological Disorders Appear To Share Tangled Metabolic Roots

Gene mutation offers clues to development of diverse neurological disorders

Scientists discover critical regulator for directing pluripotent stem cells to make blood-forming stem cells

Protein pair may be prognostic biomarker for identifying smoking-related lung cancers

LA BioMed researchers to explore influence of maternal obesity, BPA in fetal development

Research may shed light on what causes people to suffer from life-threatening anxiety disorders

Interactions between sympathetic neurons and pancreatic cells have implications for organ development

Research findings offer clues to the origin of retinal disorders later in life

New stem cell discovery may help scientists replace damaged organs

Montana scientist receives ICAAC Young Investigator Award for research on memory responses to infection

Exposing tissue to low levels of BPA linked to greater incidence of prostate cancer

New gene variant found in human and animal tissue offers a promising treatment for cancer

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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