Cell Development News and Research

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Stem cells that strongly express WNT3 are biased to develop into cells and tissues, say researchers

According to researchers at Boston Children's Hospital, stem cells that strongly express a gene called WNT3 are biased to develop into cells and tissues including pancreas, liver and bladder.

5 Jun 2013

Research suggests medullary thymic epithelial cells may have evolved from cortical-thymic TECs

Medullary thymic epithelial cells (mTECs) allow the thymus to ensure that the body's T cells are able to distinguish between potentially harmful foreign antigens and those that are produced by the body itself.

3 Jun 2013

Novel approach to create unlimited number of human red blood cells, platelets in vitro

A study led by Boston University School of Medicine has identified a novel approach to create an unlimited number of human red blood cells and platelets in vitro. In collaboration with Boston University School of Public Health and Boston Medical Center, the researchers differentiated induced pluripotent stem cells into these cell types, which are typically obtained through blood donations.

31 May 2013

GATA-3 protein plays an important role in mammalian immune response

The protein GATA-3 plays an important role in mammalian immune response, but its overall function in cell development and cancer formation is not well understood. In an effort to further define the importance of GATA-3, researchers at the University of North Carolina have traced how the protein performs important functions in CD8+T-cell type of the immune system.

27 May 2013

Students receive Addiction Science Award at 2013 Intel International Science and Engineering Fair

An exploration of electronic "screen time" and sleep on mood, memory and learning was given the top Addiction Science Award at the 2013 Intel International Science and Engineering Fair - the world's largest science competition for high school students.

20 May 2013

Better understanding of cells' development has implications in study of inflammatory diseases

Labs around the world, and a core group at Penn, have been studying recently described populations of immune cells called innate lymphoid cells. Some researchers liken them to foot soldiers that protect boundary tissues such as the skin, the lining of the lung, and the lining of the gut from microbial onslaught. They also have shown they play a role in inflammatory disease, when the body's immune system is too active.

15 May 2013

Implications for manipulating immune response for some inflammatory disorders

Cytokines are molecules produced by immune cells that induce the migration of other cells to sites of infection or injury, promote the production of anti-microbial agents, and signal the production of inflammatory mediators.

14 May 2013

New study identifies four genetic variants associated with increased risk of testicular cancer

A new study looking at the genomes of more than 13,000 men identified four new genetic variants associated with an increased risk of testicular cancer, the most commonly diagnosed type in young men today.

13 May 2013

Findings set the stage for identifying potential new drug targets, treatment strategies for AML

nvestigators for The Cancer Genome Atlas Research Network have detailed and broadly classified the genomic alterations that frequently underlie the development of acute myeloid leukemia, a deadly cancer of the blood and bone marrow.

2 May 2013

Details about genomic landscapes of AML and endometrial cancer revealed

Two studies from The Cancer Genome Atlas program reveal details about the genomic landscapes of acute myeloid leukemia and endometrial cancer.

2 May 2013

MorphoSys initiates Phase 2 clinical trial of MOR208 in B-cell acute lymphoblastic leukemia patients

Xencor announced today that MorphoSys AG has dosed the first patient in a Phase 2 clinical trial of MOR208 in B-cell acute lymphoblastic leukemia.

29 Apr 2013

Study highlights how genes can acquire, adapt to different roles in human evolution

Researchers have designed a method that can universally test for evolutionary adaption, or positive (Darwinian) selection, in any chosen set of genes, using re-sequencing data such as that generated by the 1000 Genomes Project.

19 Apr 2013

Multiple genes strongly contribute to risk for schizophrenia

Multiple genes contribute to risk for schizophrenia and appear to function in pathways related to transmission of signals in the brain and immunity, according to an international study led by Virginia Commonwealth University School of Pharmacy researchers.

10 Apr 2013

Scientists discover that drinking milk early in life could change how certain genes are expressed

It seems the ads were right. A milk mustache is a good thing to have. Animal and dairy scientists have discovered that drinking milk at an early age can help mammals throughout their lives.

6 Apr 2013

Brown fat cells protective against obesity and diabetes

Brown fat is a hot topic, pardon the pun. Brown fats cells, as opposed to white fat cells, make heat for the body, and are thought to have evolved to help mammals cope with the cold. But, their role in generating warmth might also be applied to coping with obesity and diabetes.

15 Mar 2013

Studies show prenatal nutrition may affect gene function in children's health

Pioneering studies by U. S. Department of Agriculture-funded research molecular geneticist Robert A. Waterland are helping explain how the foods that soon-to-be-moms eat in the days and weeks around the time of conception-or what's known as periconceptional nutrition-may affect the way genes function in her children, and her children's health.

13 Mar 2013

Swine study shows that moderate exercise can affect ovarian cells

A short walk around the barn might improve the future fertility of Yorkshire gilts. According to research presented by Samantha Kaminski, a graduate student at North Dakota State University, swine fetuses showed significant ovarian development after their mothers exercised.

13 Mar 2013

Minerva scientists convert established human stem cells to the elusive naïve state

Minerva Biotechnologies, a leading cancer and stem cell development company today announced a major breakthrough in human stem cell research.

8 Mar 2013

CALHM1 channel protein releases ATP to make neural taste connections

Saying that the sense of taste is complicated is an understatement, that it is little understood, even more so. Exactly how cells transmit taste information to the brain for three out of the five primary taste types was pretty much a mystery, until now.

7 Mar 2013

Insight into how Th17 cell growth influences development of immune responses

New work from the Broad Institute's Klarman Cell Observatory, Brigham and Women's Hospital, Harvard University, MIT, and Yale University expands the understanding of how one type of immune cell - known as a T helper 17 or Th17 cell - develops, and how its growth influences the development of immune responses.