Cell Development News and Research

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Protein complex shown to play pivotal role in stem cell development

Scientists at the Stanford University School of Medicine have identified a protein complex important in controlling whether embryonic stem cells retain their ability to become any cell in the body - a quality called pluripotency - or instead embark on a pathway of maturation and specialization.

2 Mar 2009

Compounds that trigger beta cell replication identified

Researchers at the Genomics Institute of the Novartis Research Foundation (GNF) have identified a set of compounds that can trigger the proliferation of insulin-producing cells in the pancreas, using sophisticated high-throughput screening techniques.

25 Feb 2009

Scientists identify stem-cell genes that help form plant organs

Plant stem-cells are master cells located at the tip of the stem and are part of a structure called the shoot apical meristem (SAM).

24 Feb 2009

Scientists discover missing link in the way cells protect themselves against cancer

Cancer Research UK scientists have discovered a missing link in the way cells protect themselves against cancer, according to research published in Genes & Development.

5 Feb 2009

Scientists unlock secrets of gene regulatory networks

A quartet of studies by researchers at the California Institute of Technology (Caltech) highlight a special feature on gene regulatory networks recently published in the Proceedings of the National Academy of Sciences ( PNAS ).

3 Feb 2009

Researchers find molecular origin of blood stem cells

A research team led by Nancy Speck, PhD, Professor of Cell and Developmental Biology at the University of Pennsylvania School of Medicine, has identified the location and developmental timeline in which a majority of bone marrow stem cells form in the mouse embryo.

12 Jan 2009

Non-pharmacologic interventions for the control of osteoporosis and obesity

The Department of Biomedical Engineering at Stony Brook University received a $1.8 million grant from the National Institutes of Health (NIH) to investigate the biologic and physical mechanisms of very low-magnitude mechanical signals and how they strengthen bone and muscle.

20 Nov 2008

Dental pulp stem cells show promise for use in cell therapy

Researchers at the Yerkes National Primate Research Center, Emory University, have discovered dental pulp stem cells can stimulate growth and generation of several types of neural cells.

12 Nov 2008

Scientists confirm a molecular clipping mechanism behind stem cell development

Stem cells don't just become a part of the liver or the brain in a flash; it takes a complex molecular choreography and requires that specific genes be switched on and off at specific times.

6 Nov 2008

Cold Spring Harbor Protocols features organ and cell culture methods

Understanding the function of organs like the brain, kidney, and reproductive tissues requires experimental systems that allow for the study and manipulation of developing cells and tissues in the laboratory.

4 Nov 2008

New stem cell tools to aid drug development

Scientists have designed, developed and tested new molecular tools for stem cell research to direct the formation of certain tissue types for use in drug development programmes.

2 Sep 2008

FDA grants IND for Davanat to treat breast cancer patient

Pro-Pharmaceuticals, Inc. has announced that the U.S. Food and Drug Administration (FDA) has granted an Investigational New Drug (IND) application for use of Davanat in combination with 5-FU to treat a breast cancer patient at the Brown Cancer Center in Louisville, Kentucky. Davanat also is being administered in Phase II clinical trials for first-line treatment of colorectal and biliary cancer patients.

28 Aug 2008

Brown fat points to new ways to fight obesity

A surprise discovery -- that calorie-burning brown fat can be produced experimentally from muscle precursor cells in mice -- raises the prospect of new ways to fight obesity and overweight, say scientists from Dana-Farber Cancer Institute.

20 Aug 2008

Bone marrow stem cells used to protect gastrointestinal tissue from autoimmune attack

Massachusetts General Hospital (MGH) investigators have found that infusions of a particular bone marrow stem cell appeared to protect gastrointestinal tissue from autoimmune attack in a mouse model.

20 Aug 2008

Universal gene signaling mechanism identified by UB molecular researchers

A novel gene signaling mechanism that controls whether a stem cell develops into its destined tissue or fails to differentiate and becomes cancer has been identified by researchers in the multi-laboratory Molecular and Structural Neurobiology and Gene Therapy Program based at the University at Buffalo.

14 Aug 2008

Findings may aid in bone marrow transplants, blood diseases

New research sheds light on the biological events by which stem cells in the bone marrow develop into the broad variety of cells that circulate in the blood. The findings may help improve the success of bone marrow transplants and develop better treatments for life-threatening blood diseases.

5 Aug 2008

Neural stem cell development may be linked to Autism

In a breakthrough scientific study published today in the Proceedings of the National Academy of Sciences, scientists at the Burnham Institute for Medical Research have shown that neural stem cell development may be linked to Autism.

30 Jun 2008

Hypertension, insulin resistance and immune suppression links

Many of the 75 million Americans with essential hypertension also develop diabetes and other complications in addition to their high blood pressure, and researchers have discovered a common molecular mechanism in a strain of rat that explains why such metabolic disorders arise together in mammals.

30 Jun 2008

Scientists discover how an injured embryo can regenerate itself

More than 80 years have passed since the German scientist Hans Spemann conducted his famous experiment that laid the foundations for the field of embryonic development. After dividing a salamander embryo in half, Spemann noticed that one half - specifically, the half that gives rise to the salamander's 'belly' (ventral) starts to wither away.

27 Jun 2008

Researchers create molecule that nudges nerve stem cells to mature

Inspired by a chance discovery during another experiment, researchers at UT Southwestern Medical Center have created a small molecule that stimulates nerve stem cells to begin maturing into nerve cells in culture.

24 Jun 2008