Cell Division News and Research

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German Research Foundation skeptical on cloning of human cells

According to a paper published in the journal Stem Cells, an American group has succeeded in inserting cell nuclei from human skin cells into human enucleated oocytes and to stimulate these new cells to undergo cell division in the laboratory.

23 Jan 2008

Cell division studies hint at future cancer therapy

When a cell's assets get divided between daughter cells, Dr. Quansheng Du wants to make sure both offspring do well.

23 Jan 2008

High blood pressure gene found

Scientists have identified the gene that sets off a sequence of events in the blood vessels of otherwise healthy adults that can lead to high blood pressure.

11 Jan 2008

Asf1, the protein that oversees DNA replication and packaging in the cell

At the Institut Curie, the CNRS team of Genevieve Almouzni has just discovered how the protein Asf1 ensures the correct (re)organization of duplicated DNA. During DNA replication, all the information in the mother cell must be transmitted to the daughter cells.

11 Jan 2008

New insight into factors that drive muscle-building stem cells

A report in the January issue of Cell Metabolism, a publication of Cell Press, provides new evidence explaining how stem cells known as satellite cells contribute to building muscles up in response to exercise.

9 Jan 2008

Discovery of 480 genes that control human cell division

A team of U.S., Israeli and German scientists used computational biology techniques to discover 480 genes that play a role in human cell division and to identify more than 100 of those genes that have an abnormal pattern of activation in cancer cells.

8 Jan 2008

Differentiation blocked in tumor stem cells

A new comparison of normal stem cells and cancer stem cells reveals that the cancer stem cells are abnormally trapped at an early stage of development.

8 Jan 2008

Copy number variation may stem from replication misstep

Genome rearrangements, resulting in variations in the numbers of copies of genes, occur when the cellular process that copies DNA during cell division stalls and then switches to a different genetic "template," said researchers at Baylor College of Medicine in Houston in a report that appears today in the journal Cell.

28 Dec 2007

Scientists identifiy elusive telomere RNA subunit in single cell model

The Stowers Institute's Baumann Lab has identified the long-sought telomerase RNA gene in a single-cell research model.

28 Dec 2007

How molecular muscles help cells divide

Time-lapse videos and computer simulations provide the first concrete molecular explanation of how a cell flexes tiny muscle-like structures to pinch itself into two daughter cells at the end of each cell division, according to a report in Science Express.

17 Dec 2007

Scientists develop new drug to outflank cancer resistance

A new drug has shown promising results against breast and prostate cancer cells and tumours that are resistant to conventional hormone-based treatments, according to research published in the British Journal of Cancer.

12 Dec 2007

Explanation on resistance to taxane class of drugs

Scientists have uncovered critical new details about the mechanisms that modulate the response of ovarian cancer cells to chemotherapy.

10 Dec 2007

Stem cell technology pioneer, Plasticell secures funding

Plasticell is a biotechnology company that has developed and holds exclusive intellectual property rights for two complementary systems in the fields of stem cell research and regenerative medicine.

29 Nov 2007

RNA polymerase III mutation disrupts organ growth

The cellular mechanism that turns DNA into all of the thousands of proteins that make up a human body is itself both intricate and interesting.

27 Nov 2007

Variant of CDC2 gene may be potential risk marker for Alzheimer's

A variant of the gene CDC2 could possibly be used as a risk marker for Alzheimer’s disease.

20 Nov 2007

New explanation for how regulatory networks of genes evolved

When ancient retroviruses slipped bits of their DNA into the primate genome millions of years ago, they successfully preserved their own genetic legacy.

15 Nov 2007

Telomerase enzyme structure provides significant new target for anti-cancer therapies

Inappropriate activation of a single enzyme, telomerase, is associated with the uncontrollable proliferation of cells seen in as many as 90 percent of all of human cancers. Since the mid-1990s, when telomerase was first identified in human tumors, scientists have eyed the enzyme as an ideal target for developing broadly effective anti-cancer drugs.

14 Nov 2007

How one virus mimicks a normal cellular protein to replicate successfully

Both viruses and cancers subvert the growth-control machinery in a cell to serve their own needs.

1 Nov 2007

Emerging cancer therapies and novel targets

What are the cancer drugs of tomorrow and how will they be developed? At the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, researchers will present some answers to these and other pressing questions regarding emerging cancer therapeutics.

25 Oct 2007

piRNAs play an important role in controlling gene function

A study by researchers at the Yale Stem Cell Center for the first time demonstrates that piRNAs, a recently discovered class of tiny RNAs, play an important role in controlling gene function, it was reported this week in Nature.

25 Oct 2007