Cell Line News and Research

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Fluorescent protein tool may speed identification of molecular changes that reveal cells' inner workings

Scientists at Johns Hopkins and the University of Texas Medical Branch have created a new tool that easily reveals when and where a key cellular signal is active.

16 Nov 2004

Enzyme that normally alters the activity of other protein molecules in cells may also help prevent cancer

The enzyme is known as PTPRO (for “protein tyrosine phosphatase receptor-type O”). When the gene responsible for producing PTPRO is silenced, as can happen in lung cancer, for example, the amount of the enzyme drops, allowing the cells to grow when they shouldn’t.

11 Nov 2004

U.S. Patent for generating genetically altered antibody producing cell lines

Morphotek announced today the issuance of United States Patent 6,808,894 covering the generation of genetically enhanced antibody producer cell lines.

8 Nov 2004

Scientists are testing the effectiveness of a new type of flu vaccine

The experimental vaccine instead relies on a cell line drawn from insects known as silk moths, which are better known for their role as pests attacking crops such as corn, cotton, barley and alfalfa.

25 Oct 2004

Potential new protein marker for prognosis of breast and ovarian cancer

The researchers matched tumor samples to outcomes in about 100 patients diagnosed with either breast or ovarian cancer and found that a low level of Rab25 protein on a patient's cancer sample was associated with a better clinical outcome in both cancer types.

24 Oct 2004

Exercise protects brain cells affected by Parkinson's

In an animal model of Parkinson's, exercise prevents degeneration of nerve cells that are normally impaired or destroyed by the disease, according to University of Pittsburgh researchers.

24 Oct 2004

Comprehensive study raises questions about "demethylation" agents

Agents believed to selectively "restart" genes that limit cancer's growth -- a potential treatment option already in early clinical studies -- instead turn off as many genes as they turn on, a team of researchers from the National Cancer Institute and Johns Hopkins has discovered.

18 Oct 2004

Researchers have integrated heart cells grown from human embryonic stem cells into a host heart

Researchers at the Technion-Israel Institute of Technology and Rambam Medical Center have demonstrated that heart cells grown from human embryonic stem cells can integrate into the host heart and help regulate its activity, becoming in effect a biological pacemaker.

27 Sep 2004

Arsenic could be toxic at much lower levels than previously thought

Arsenic could be toxic at much lower levels than previously thought, suggesting that the new EPA drinking water standard of 10 parts per billion might still be too high, according to a team of researchers at Dartmouth Medical School.

26 Sep 2004

Drug combo may have a greater impact on cancer development

Cancer researchers have long suggested that new targeted drugs may work best when paired with other therapies. In a new study published today in Cancer Research, scientists have taken some of the first steps to demonstrate this synergy in mouse and cell line models.

16 Sep 2004

Gene therapy holds much promise for treating aggressive human superficial bladder cancer

Gene therapy that causes the bladder to act like a “bioreactor” to produce and secrete the anti-cancer agent interferon-alpha has shown dramatic benefits in preclinical tests, say researchers at The University of Texas M. D. Anderson Cancer Center.

8 Sep 2004

MorphoSys obtains license on human cell line technology for use in its antibody research

MorphoSys has announced today a non-exclusive license agreement with Dutch biotechnology company Crucell and DSM Biologics.

8 Sep 2004

Pioneering work with human embryonic stem cells could speed up development of new treatments for Parkinson’s and diabetes

Pioneering work with human embryonic stem (hES) cells could speed up the development of new treatments for a range of degenerative disorders such as Parkinson’s disease and diabetes according to Dr Stephen Minger of King’s College London, speaking today at the BA Festival of Science.

8 Sep 2004

Embryonic stem cell therapy show benefits in rebuilding damaged heart

Despite improvements in earlier diagnosis and treatment, cardiovascular disease is far and away the leading cause of death in the U.S. and the world.

18 Aug 2004

New screening technique to look for genes that change patients' responses to cancer drugs and other medications

Scientists have developed a new screening technique to help them look for genes that change patients' responses to cancer drugs and other medications.

3 Aug 2004

New glycan arrays discover autoimmunogenic activities of SARS-CoV

Researchers in New York City and Guangzhou, China applied the rapidly-developing carbohydrate microarray technology to study an inactivated SARS-coronavirus (SARS-CoV) vaccine and discovered autoimmunogenic activity of this newly identified human viral pathogen.

2 Aug 2004

University of Cambridge to generate antibodies

The University of Cambridge has announced a licensing agreement with Human-Human Hybridoma, Inc. (3H) to exploit a human myeloma cell line (Karpas-707H) that can be used in research and for the production of human monoclonal antibodies.

15 Jun 2004

Neuroscientists have overcome a major obstacle in gene therapy research

Northwestern University neuroscientists have overcome a major obstacle in gene therapy research. They've devised a method that will safely deliver and regulate expression of therapeutic genes introduced into the central nervous system to treat Parkinson's disease and other neurodegenerative diseases.

5 Jun 2004

Improvement of Parkinson’s disease symptoms when neurorestorative molecule pumped to the center of the brain

A recent study has shown clinical improvement of Parkinson’s disease symptoms after long-term infusion of a neurorestorative molecule, pumped directly to the center of the brain. The study will be presented at the American Academy of Neurology 56th Annual Meeting in San Francisco, Calif., April 24 – May 1, 2004.

27 Apr 2004

Wine, beer and tea have contributed to a significant decrease in breast cancer

Numerous studies have been published showing that consuming alcohol increases the risk for breast cancer. That’s what makes a new research finding from Portugal so intriguing. The study has determined that certain compounds found in wine, beer (and tea) have contributed to a significant decrease in breast cancer cell proliferation.

19 Apr 2004

Cell Line News and Research

Fluorescent protein tool may speed identification of molecular changes that reveal cells' inner workings

Enzyme that normally alters the activity of other protein molecules in cells may also help prevent cancer

U.S. Patent for generating genetically altered antibody producing cell lines

Scientists are testing the effectiveness of a new type of flu vaccine

Potential new protein marker for prognosis of breast and ovarian cancer

Exercise protects brain cells affected by Parkinson's

Comprehensive study raises questions about "demethylation" agents

Researchers have integrated heart cells grown from human embryonic stem cells into a host heart

Arsenic could be toxic at much lower levels than previously thought

Drug combo may have a greater impact on cancer development

Gene therapy holds much promise for treating aggressive human superficial bladder cancer

MorphoSys obtains license on human cell line technology for use in its antibody research

Pioneering work with human embryonic stem cells could speed up development of new treatments for Parkinson’s and diabetes

Embryonic stem cell therapy show benefits in rebuilding damaged heart

New screening technique to look for genes that change patients' responses to cancer drugs and other medications

New glycan arrays discover autoimmunogenic activities of SARS-CoV

University of Cambridge to generate antibodies

Neuroscientists have overcome a major obstacle in gene therapy research

Improvement of Parkinson’s disease symptoms when neurorestorative molecule pumped to the center of the brain

Wine, beer and tea have contributed to a significant decrease in breast cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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