Cell Metabolism News and Research

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Insulin resistance could be due to changes in specific subtype of fat cells, study suggests

It is well known that fat cells can influence our sensitivity to insulin. Now, researchers at Karolinska Institutet in Sweden have discovered that there are three different subtypes of mature fat cells in white adipose tissue and that it is only one of these, called AdipoPLIN, that responds to insulin.

10 Aug 2021

Resistance exercise regulates fat cell metabolism at a molecular level, study finds

Findings from a new University of Kentucky College of Medicine and College of Health Sciences study add to growing evidence that resistance exercise has unique benefits for fat loss.

9 Aug 2021

Research reveals a microRNA network as putative mediators of myocardial reductive stress

Last year, University of Alabama at Birmingham researchers reported that reductive stress -; an imbalance in the normal oxidation/reduction homeostasis -; caused pathological changes associated with heart failure in a mouse model.

6 Aug 2021

UCLA professor honored for contributions to the field of hematology

Dr. Elizabeta Nemeth, professor of medicine and director of the Center for Iron Disorders at the David Geffen School of Medicine at UCLA, has been awarded the 2021 William Dameshek Prize by the American Society of Hematology (ASH) for her contributions to the field of hematology.

2 Jul 2021

Lowering iron content in fat cells prevented mice from gaining excess weight

Lowering iron content in fat cells prevented mice fed a high-fat diet from gaining excess weight and developing associated health problems by limiting the amount of lipids absorbed by the intestines, UT Southwestern scientists report in a new study. The findings, published online in Cell Metabolism, could eventually lead to new strategies to protect people against obesity and related diseases.

29 Jun 2021

New technique can measure metabolic process at the single-cell level

Understanding cellular metabolism - how a cell uses energy- could be key to treating a wide array of diseases, including vascular diseases and cancer.

18 Jun 2021

Study finds molecular switch that controls the ability of organisms to adapt to low nutrient levels

Getting energy and nutrients from the environment - that is, eating - is such an important function that it has been regulated through sophisticated mechanisms over hundreds of millions of years. Some of these mechanisms are only now beginning to be unraveled.

16 Jun 2021

Repressing a protein that facilitates DNA repair to potentiate chemotherapy

Chemotherapy kills tumor cells by causing damage to them. One of the most effective ways of causing damage is to prevent the two DNA strands from separating so that the cellular machinery cannot read the instructions written in the genes.

15 Jun 2021

Study elucidates how Omega-3 fatty acids poison tumor cells

So-called "good fatty acids" are essential for human health and much sought after by those who try to eat healthily. Among the Omega-3 fatty acids, DHA or docosahexaenoic acid is crucial to brain function, vision and the regulation of inflammatory phenomena.

11 Jun 2021

Discovery suggests new pathways for safeguarding the immune system’s ability to fight cancer

In order for cancer to grow and spread, it has to evade detection by our immune cells, particularly specialized "killer" T cells.

10 Jun 2021

ONK Therapeutics and Trinity researchers seek to improve cellular therapies for treating cancer

ONK Therapeutics Ltd, an innovative natural killer (NK) cell therapy company, today announced that it has been awarded an Innovation Partnership Programme grant by Enterprise Ireland (EI) to fund collaborative research at Trinity College Dublin, Ireland, led by Dr. David Finlay to optimize the metabolism and engineering of NK cells for improved cancer therapies.

8 Jun 2021

New chip mimicking bovine endometrium could play key role in cattle’s pregnancy success

To investigate factors that can jeopardize pregnancy success in cattle, researchers at the University of São Paulo (USP) in Brazil used a kind of chip to mimic the environment of the endometrium, the tissue that lines the inside of the uterus.

8 Jun 2021

Study confirms the importance of low-protein, high-carbohydrate diet

Researchers at the University of Sydney's Charles Perkins Centre conducted the largest ever study of nutrient interactions by examining the health of mice on 33 different diets containing various combinations of protein to carbs, and different sources of carbohydrate.

8 Jun 2021

Study explores therapeutic potential of exploiting autophagy cascade against COVID-19

Researchers recently reviewed current knowledge on links between autophagy and coronaviruses and how this knowledge can be used to repurpose autophagy modulators as potential treatment options for COVID-19. The review is published in the journal Frontiers in Microbiology.

7 Jun 2021

Gut-brain communication by distinct nerve cells differently controls satiety and blood sugar levels

The gut and the brain communicate with each other in order to adapt satiety and blood sugar levels during food consumption.

2 Jun 2021

Targeting mTOR pathway can improve the effectiveness of chemotherapies for pediatric brain cancer

Two experimental drug approaches that target vulnerabilities in cancer cell metabolism may extend survival and enhance the effectiveness of standard chemotherapies for a highly aggressive type of pediatric brain cancer.

21 May 2021

A potential treatment to prevent obesity-related liver damage

One of the especially dangerous health risks of being extremely overweight occurs when an obese person begins to accumulate fat in their liver.

18 May 2021

Sepsis can cause alterations in the functioning of defense cells that lead to death

An article published in Frontiers in Immunology suggests that sepsis can cause alterations in the functioning of defense cells that persist even after the patient is discharged from hospital.

12 May 2021

Sepsis can cause alterations in the functioning of defense cells that lead to death

An article published in Frontiers in Immunology suggests that sepsis can cause alterations in the functioning of defense cells that persist even after the patient is discharged from hospital.

12 May 2021

Could in vitro glycoengineering help produce better SARS-CoV-2 spike candidates for vaccine research?

A vexing problem in the development of vaccines has been the need to achieve the right glycosylation profile for the viral antigens. A new study, recently released as a preprint on the bioRxiv* server, shows how a sequential cell-free approach produced complex N-glycans from simpler types, in a one-pot reaction.

4 May 2021

Cell Metabolism News and Research

Insulin resistance could be due to changes in specific subtype of fat cells, study suggests

Resistance exercise regulates fat cell metabolism at a molecular level, study finds

Research reveals a microRNA network as putative mediators of myocardial reductive stress

UCLA professor honored for contributions to the field of hematology

Lowering iron content in fat cells prevented mice from gaining excess weight

New technique can measure metabolic process at the single-cell level

Study finds molecular switch that controls the ability of organisms to adapt to low nutrient levels

Repressing a protein that facilitates DNA repair to potentiate chemotherapy

Study elucidates how Omega-3 fatty acids poison tumor cells

Discovery suggests new pathways for safeguarding the immune system’s ability to fight cancer

ONK Therapeutics and Trinity researchers seek to improve cellular therapies for treating cancer

New chip mimicking bovine endometrium could play key role in cattle’s pregnancy success

Study confirms the importance of low-protein, high-carbohydrate diet

Study explores therapeutic potential of exploiting autophagy cascade against COVID-19

Gut-brain communication by distinct nerve cells differently controls satiety and blood sugar levels

Targeting mTOR pathway can improve the effectiveness of chemotherapies for pediatric brain cancer

A potential treatment to prevent obesity-related liver damage

Sepsis can cause alterations in the functioning of defense cells that lead to death

Sepsis can cause alterations in the functioning of defense cells that lead to death

Could in vitro glycoengineering help produce better SARS-CoV-2 spike candidates for vaccine research?

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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