Cell Nucleus News and Research

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New study helps explain why lung tumors turn aggressive

Lung cancer is the number 1 killer among cancers, especially when it is of the non-small cell type. Among these, adenocarcinomas are the most common and aggressive type. These tumors also show a strong tendency to show dedifferentiation, or loss of the features that characterize a mature lung cell.

28 Aug 2019

Chlamydia vaccine shows promise after a successful clinical trial

A vaccine against the sexually transmitted infection (STI) chlamydia is now a substantial step closer to reality after successfully passing its Phase 1 clinical trial.

14 Aug 2019

Researchers identify epigenetic mechanism that may strongly influence healthy aging

Researchers at the Max Delbrueck Center for Molecular Medicine have identified an epigenetic mechanism that appears to strongly influence healthy aging.

9 Aug 2019

Study forms basis for therapeutic strategies to combat cancers caused by HMGA1a

The researchers led by Professor Raphael Stoll therefore expect their results to form a basis for future therapeutic strategies to combat cancers caused by HMGA1a.

30 Jul 2019

Novel insight into microRNA function can be crucial for the development of gene therapy

Scientists at the University of Eastern Finland and the University of Oxford have shown that small RNA molecules occurring naturally in cells, i.e. microRNAs, are also abundant in cell nuclei.

18 Jul 2019

Nanoparticles used to deliver CRISPR gene editing tools into the cell

Researchers from Tufts University and the Chinese Academy of Sciences have developed a novel method to effectively deliver the CRISPR/Cas9 (clustered regularly interspaced short palindromic repeat (CRISPR) associated protein 9) gene editing tools into the liver for genetic studies.

15 Jul 2019

Researchers use genetically manipulated virus to combat prostate cancer

Researchers at the São Paulo State Cancer Institute in Brazil have succeeded in using a genetically manipulated virus to destroy tumor cells upon injection into mice with prostate cancer.

27 Jun 2019

New study could change our understanding of how stem cells differentiate

A pioneering new study led by Florida State University biologists could fundamentally change our understanding of how embryonic stem cells differentiate into specific cell types.

24 Jun 2019

Researchers reveal underlying mechanism that protects genetic transcripts in cells

The cell contains transcripts of the genetic material, which migrate from the cell nucleus to another part of the cell. This movement protects the genetic transcripts from the recruitment of "spliceosomes".

13 Jun 2019

Still-to-be-approved drug proves to be new option for treating active rheumatoid arthritis

In a large-scale, international study led by renowned rheumatologist Josef Smolen from the Department of Medicine III, a still-to-be-approved drug containing the selective janus kinase inhibitor upadacitinib has proved itself to be a new option for treating active rheumatoid arthritis.

7 Jun 2019

Study searches for the origins of depressive symptoms in Huntington's disease

About 40% of the affected patients with Huntington's disease -a neurodegenerative pathology- show depression symptoms, even in early stages before the apparition of the typical motor symptoms of the disease.

31 May 2019

Tumor-fighting combination targets aggressive form of brain cancer

Researchers have paired a specialized diet and a tumor-fighting drug and found the non-toxic combination helps to destroy the two major cells found in an aggressive form of brain cancer, the team reports in the online edition of the Nature group journal Communications Biology.

31 May 2019

Study sheds light on design of pharmacological strategies to treat depression in Huntington's disease

About 40 % of the affected patients with Huntington's disease -a neurodegenerative pathology- show depression symptoms, even in early stages before the apparition of the typical motor symptoms of the disease.

31 May 2019

Research could lead to new treatments for people with autoimmune disorders

The immune system is programmed to rid the body of biological bad guys--like viruses and dangerous bacteria--but its precision isn't guaranteed. In the tens of millions of Americans suffering from autoimmune diseases, the system mistakes normal cells for malicious invaders, prompting the body to engage in self-destructive behavior.

29 May 2019

New laboratory test has potential to accurately predict spread of breast cancer

Researchers at The Johns Hopkins University and other institutions report that a new laboratory test that induces cancer cells to squeeze through narrow spaces has the potential to accurately predict which breast cancers and other solid tumors are likely to spread, or metastasize, to other sites.

From Johns Hopkins Medicine 29 May 2019

Cell Nucleus News and Research

New study helps explain why lung tumors turn aggressive

Chlamydia vaccine shows promise after a successful clinical trial

Researchers identify epigenetic mechanism that may strongly influence healthy aging

Study forms basis for therapeutic strategies to combat cancers caused by HMGA1a

Novel insight into microRNA function can be crucial for the development of gene therapy

Nanoparticles used to deliver CRISPR gene editing tools into the cell

Researchers use genetically manipulated virus to combat prostate cancer

New study could change our understanding of how stem cells differentiate

Researchers reveal underlying mechanism that protects genetic transcripts in cells

Still-to-be-approved drug proves to be new option for treating active rheumatoid arthritis

Study searches for the origins of depressive symptoms in Huntington's disease

Tumor-fighting combination targets aggressive form of brain cancer

Study sheds light on design of pharmacological strategies to treat depression in Huntington's disease

Research could lead to new treatments for people with autoimmune disorders

New laboratory test has potential to accurately predict spread of breast cancer

Epigenetic research provides new approaches to cancer combination therapies

Provocation of obsessive thoughts induces physiological brain changes in 64-year-old man with OCD

Scientists use gold nanoparticles to edit genes tied to HIV, inherited blood disorders

Study clarifies how 3D organization of genome is regulated at onset of skeletal muscle formation

Spatial configuration of the genome is not inherited, but set up during embryogenesis

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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