Cell Proliferation News and Research

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Study identifies a novel druggable signaling molecule involved in obesity and diabetes

More than 40% of Americans are considered obese, and the trend continues to grow. The treatments or preventive options for obesity and obesity-associated diseases are limited.

26 May 2023

Researchers explore the possibility of treating lung cancer by targeting telomeres

Healthy cells can only divide a limited number of times during an organism's lifetime. In contrast, tumor cells are immortal: they proliferate indefinitely and uncontrollably, and this is the defining characteristic of cancer.

26 May 2023

GPR141 drives breast tumorigenesis by inducing tumor cell properties via the p-mTOR1/p53 axis

A new research paper was published in Oncotarget's Volume 14 on May 19, 2023, entitled, "G-protein-coupled receptor 141 mediates breast cancer proliferation and metastasis by regulating oncogenic mediators and the p-mTOR/p53 axis."

23 May 2023

Researchers receive $2.3 million to continue development of a new ‘glyco-immune’ checkpoint inhibitor

Researchers from Rice University and Baylor College of Medicine are hoping a first-of-its-kind "glyco-immune" checkpoint inhibitor could be the key to stopping bone cancer metastasis for breast cancer survivors.

19 May 2023

Identify the underlying mechanism associated with the initiation of focal amplification in breast cancer

Identifying the underlying mechanism associated with the initiation of focal amplification in breast cancer.

19 May 2023

Unlocking the gut clock: How circadian rhythms and gut microbiota team up to impact human health

Research investigates the connection between circadian rhythms and specific microbial patterns in various disease contexts, emphasizing the need for further studies.

15 May 2023

Protein inhibition could offer new strategies for treating severe asthma

Inhibiting a protein on the surface of immune cells could offer new strategies for treating severe asthma, Cleveland Clinic researchers found.

10 May 2023

High-grade gliomas remodel neural circuits: promoting tumor progression and impaired cognition

Researchers investigated whether functional connectivity between glioblastoma and the brain affected neural circuits.

9 May 2023

Finnish mitochondrial disease of newborns shows cancer-like changes in proliferating cells

A study found that a mitochondrial disease of newborns shows cancer-like changes in proliferating cells, causing tissues to age prematurely.

3 May 2023

Study evaluates the effects of phenolic compounds in extra virgin olive oil on skin health

Researchers evaluated the effects of phenolic compounds in extra virgin olive oil on human fibroblasts.

27 Apr 2023

The potential anti-cancer and antioxidant properties of walnuts

Researchers reviewed current literature to examine walnuts' potential antioxidant and anti-cancer properties.

25 Apr 2023

Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

A recent study reveals that DCAF1 is overexpressed and phosphorylates EZH2 in colon cancer cells.

18 Apr 2023

Rapamycin and other rapalogs have potential to delay cancer

A new research perspective was published in Oncotarget's Volume 14 on April 14, 2023, entitled, "Cancer prevention with rapamycin."

18 Apr 2023

Antioxidant-rich phenolic compounds: A key to disease prevention, gut health, and brain homeostasis

Researchers report on the benefits of consuming dietary phenols and their relationship with the intestinal microbiome.

10 Apr 2023

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

Understanding how cancer develops is critical for designing effective, personalized cancer therapies. Researchers have known for years that cancer begins with mutations in certain types of genes.

6 Apr 2023

Interplay between Western diet, gut microbiota, and cancer development

In a review article published in the journal Seminars in Immunology, scientists have explored the relationship between the Western diet, gut microbiota, and cancer development.

4 Apr 2023

Can the Mediterranean diet and physical exercise improve the quality of life for cancer patients?

Researchers reviewed existing literature on the benefits of adopting Mediterranean diets against inflammatory conditions and cancer.

3 Apr 2023

New review examines link between HDLC and different types of cancer

Researchers summarized studies on the association between high-density lipoprotein cholesterol and different types of cancer

29 Mar 2023

Study investigates how loss of angulin-1/LSR affects the malignancy of lung adenocarcinoma

A new research paper was published in Oncotarget's Volume 14 on March 24, 2023, entitled, "Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells."

29 Mar 2023

Study finds correlations between how and which organ systems are affected in individuals with new epileptic disorder

A recent study from Texas Children's Hospital and Baylor College of Medicine has expanded the clinical spectrum of a new epileptic disorder called Intellectual Developmental Disorder with Macrocephaly, Seizures, and Speech Delay (IDDMSSD) with the identification of the first recurrently affected residue identified in the protein kinase domain of PAK1 protein.

29 Mar 2023

Cell Proliferation News and Research

Study identifies a novel druggable signaling molecule involved in obesity and diabetes

Researchers explore the possibility of treating lung cancer by targeting telomeres

GPR141 drives breast tumorigenesis by inducing tumor cell properties via the p-mTOR1/p53 axis

Researchers receive $2.3 million to continue development of a new ‘glyco-immune’ checkpoint inhibitor

Identify the underlying mechanism associated with the initiation of focal amplification in breast cancer

Unlocking the gut clock: How circadian rhythms and gut microbiota team up to impact human health

Protein inhibition could offer new strategies for treating severe asthma

High-grade gliomas remodel neural circuits: promoting tumor progression and impaired cognition

Finnish mitochondrial disease of newborns shows cancer-like changes in proliferating cells

Study evaluates the effects of phenolic compounds in extra virgin olive oil on skin health

The potential anti-cancer and antioxidant properties of walnuts

Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

Rapamycin and other rapalogs have potential to delay cancer

Antioxidant-rich phenolic compounds: A key to disease prevention, gut health, and brain homeostasis

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

Interplay between Western diet, gut microbiota, and cancer development

Can the Mediterranean diet and physical exercise improve the quality of life for cancer patients?

New review examines link between HDLC and different types of cancer

Study investigates how loss of angulin-1/LSR affects the malignancy of lung adenocarcinoma

Study finds correlations between how and which organ systems are affected in individuals with new epileptic disorder

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

Natural products: the next frontier in drug discovery

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