Cell Signaling News and Research

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Cell signaling is vital for cells to communicate and coordinate their activities, not just in the human body, but in all organisms. There are thousands of signaling pathways, ranging from protein homeostasis to carcinogenesis and biofilm formation.

Study investigates a new mechanism of pyrethroid derivatives-moderated programmed cell death

A new research paper was published in Oncotarget's Volume 13 on December 17, 2022, entitled, "The role of pyrethroid derivatives in autophagy and apoptosis crosstalk signaling and potential risk for malignancies."

29 Dec 2022

Researchers discover how segmentation clock genes instruct the tempo of spine formation

One of the most dramatic phases of fetal development occurs as previously unstructured collections of rapidly dividing precursor cells begin forming the embryo's spine.

15 Dec 2022

Study looks at the possibility of promoting hair cell regeneration using cell reprograming

About 430 million people around the world experience disabling hearing loss. In the United States, approximately 37.5 million adults report some trouble hearing. Hearing loss can happen when any part of the ear or the nerves that carry information on sounds to the brain do not work in the usual way.

8 Dec 2022

Chemical residue from commercial dishwashers causes gut epithelial barrier damage

Residue from rinse agents is left behind on dishes after they are cleaned in professional-grade dishwashers.

1 Dec 2022

Broccoli and sprouts improve gut microbiota and reduce inflammation in IBD

Recently, scientists reviewed the role of sulforaphane from cruciferous vegetables (e.g., broccoli) in preventing IBD by regulating inflammation and altering the gut microbiome.

29 Nov 2022

Study provides a key link between the social environment and healthy brains

As people age, maintaining a positive and predictable social environment becomes more and more important. For instance, keeping close ties with friends and family has been identified as one of the key ingredients to healthy aging.

24 Nov 2022

Shared genetic effects between the autoimmune disease systemic lupus erythematosus and the clinical consequences of COVID-19

Researchers identified a genetic association signal, via genome-wide association studies, between severe COVID-19 with systemic lupus erythematosus, an autoimmune disease.

7 Nov 2022

Researchers find the root of immunosuppression and chemoresistance in TNBC tumors

Triple-negative breast cancer (TNBC) tumors gain immunosuppression and chemoresistance through interactions between interleukin 34 and myeloid-derived suppressor cells, researchers find.

1 Nov 2022

Study reveals how a cell signaling molecule can help oral cancer cells acquire high motility

The process of metastasis is when cancer cells gain motility and spread to other sites of the body. Because this is one of the main causes of cancer-related deaths, researchers have aimed to develop therapeutic strategies that can block metastasis.

18 Oct 2022

Study reviews hydroxychloroquine and remdesivir antiviral potency against SARS‐CoV‐2

In a new study, researchers outlined the synthesis and the possible mechanism of action (MOA) of two potential severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) repurposing drug candidates.

17 Oct 2022

Study explores cell signaling dysregulation and COVID-19 severity

Researchers assessed the impact of dysregulation in cell signaling events on coronavirus disease 2019 (COVID-19) severity.

12 Oct 2022

Cat allergen immunotherapy works better and more quickly when combined with monoclonal antibody

An experimental approach to enhancing a standard cat allergy treatment made it more effective and faster acting, and the benefits persisted for a year after treatment ended, a study supported by the National Institutes of Health has found.

11 Oct 2022

Study identifies a potential biological marker to help diagnose postpartum depression

A federally funded study led by Johns Hopkins Medicine researchers discovered that communication among cells is altered in pregnant women who go on to develop postpartum depression (PPD) after giving birth.

4 Oct 2022

Study reveals a promising therapeutic target for spinocerebellar ataxia type 14

Spinocerebellar ataxias are a group of neurodegenerative diseases characterized by the degeneration of Purkinje cells, a major class of neurons in the cerebellum.

3 Oct 2022

Novel technique helps to detangle how phosphorylation regulates cellular events

Each day, millions of biological processes occur in our body at a cellular level. Studying these processes can help us learn more about how cells function, a field that has continued to intrigue researchers.

30 Sep 2022

Exploring biological mechanisms behind the link between obesity prior to pregnancy and elevated risk of pediatric ALL

Published in Leukemia Research, University of Minnesota Medical School researchers explored the possible biological mechanisms that could explain the association between being overweight or obese prior to pregnancy and the increased risk of acute lymphoblastic leukemia (ALL) in children.

28 Sep 2022

New drug induces similar effects as exercise to aid in the treatment of locomotor frailty

Maintaining a regular workout routine can help you look and feel great – but did you know that exercise also helps maintain your muscles and bones? People who are unable to engage in physical activity experience weakening of the muscles and bones, a condition known as locomotor frailty.

13 Sep 2022

Interferon response induced by Omicron BA.1 and BA.5 prevents influenza A infection

In a recent study posted to the bioRxiv* preprint server, researchers in Germany and the United Kingdom investigated the interferon responses induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant and SARS-CoV-2 Omicron sub-variants BA.1 and BA.5, and their efficacy in protecting cells from influenza A virus super-infection.

12 Sep 2022

Study provides a potential game-changer in assessing treatment response in pancreatic cancer patients

The statistics for pancreatic cancer are sobering. With a five-year survival rate of only 9%, incidence of the most common type, pancreatic ductal adenocarcinoma (PDAC), is growing and projected to be the second cause of cancer deaths by 2030.

8 Sep 2022

Research identifies a promising path to developing therapies to treat esophageal tumors

Research led by Case Western Reserve University has identified a promising path to developing therapies to treat esophageal tumors––a form of cancer that not only is among the most deadly, but also has been occurring at increasing rates over the past decade.