Cell Signaling News and Research

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Cell signaling is vital for cells to communicate and coordinate their activities, not just in the human body, but in all organisms. There are thousands of signaling pathways, ranging from protein homeostasis to carcinogenesis and biofilm formation.

Study provides better understanding of how to treat individuals affected by copper imbalances

Copper is an essential part of our lives. From copper pipes and wires - to important copper-containing proteins in the body, copper is necessary for healthy growth and neurological development.

2 May 2007

Green tea may help prevent bone destruction in arthritis

In rheumatoid arthritis, a person's own immune system attacks the joints by activating the synovial tissue that lines the body's movable joints, causing inflammation, swelling, pain and eventually erosion of the bone and cartilage and deformation of the joint.

30 Apr 2007

New mechanism identified for resistance to targeted lung cancer drugs

An international research team, led by investigators from the Massachusetts General Hospital (MGH) Cancer Center and Dana-Farber Cancer Institute (DFCI), has found a new way that some lung tumors become resistant to treatment with targeted therapy drugs like Iressa and Tarceva.

27 Apr 2007

New methods for treating lung cancer cells that have become resistant to new anti-cancer agents

Researchers at the Ireland Cancer Center of University Hospitals Case Medical Center have developed methods for treating lung cancer cells that have become resistant to new anti-cancer agents.

24 Apr 2007

Renovis and Pfizer extend research collaboration

Renovis has announced an agreement with Pfizer to extend the term of the companies' worldwide collaboration to research, develop and commercialize small molecules that target the vanilloid receptor, VR1.

11 Apr 2007

Research defines the cancer role for protein Gab-2

A protein known for its ability to "bridge" interactions between other cellular proteins may spur metastasis in breast cancer, the disease's deadliest stage, a study from Burnham Institute for Medical Research has found.

22 Feb 2007

Cell pathway identified which plays critical role in colon cancer

For the one in 18 men and women who will be diagnosed with cancer of the colon and rectum during their lifetime and over 150,000 people diagnosed on a yearly basis, today's genetic research news offers some optimism.

20 Feb 2007

FoxOs shown to be potential new targets for cancer drugs

In an elegant, multiple-gene knockout experiment, a team of Boston scientists has discovered that a trio of molecules, called FoxOs, are fundamentally critical in preventing some cancers, maintaining blood vessel stability, and in keeping blood-forming stem cells healthy.

29 Jan 2007

SH2B1 protein plays a key role in controlling body weight, response to insulin and leptin

A single protein in brain cells may act as a linchpin in the body's weight-regulating system, playing a key role in the flurry of signals that govern fat storage, sugar use, energy balance and weight, University of Michigan Medical School researchers report.

29 Jan 2007

Food can have an impact in preventing cancer

With cancer, researchers don't believe "you are what you eat"; that disease is always a direct result of what is, or what isn't, on your dinner plate.

14 Nov 2006

Scientists discover how androgen plays a role in the development of prostate cancer

Scientists have discovered for the first time a specific biochemical pathway by which the sex hormone, androgen, increases levels of harmful chemicals called reactive oxygen species (ROS) in the prostate gland that play a role in the development of prostate cancer.

8 Nov 2006

New target for cancer therapy identified by Australian researchers

A new target for cancer therapy has been identified by Monash University scientists investigating the cell signalling pathways that turn on a gene involved in cancer development.

21 Sep 2006

Dual-mode nanoscale imaging yields new details of cellular events

To create drugs capable of targeting malignancies, scientists must first decode exactly how a cell or a group of cells communicates with other cells and reacts to a broad spectrum of complex biomolecules surrounding it.

21 Aug 2006

Cancer stem cells spur glioma angiogenesis, could hold key to brain tumor therapy

Stem cell-like glioma cancer cells that share many characteristics with normal stem cells propel the lethal growth of brain cancers by promoting tumor blood vessel formation, and may hold the key to treating these deadly cancers.

15 Aug 2006

New tool to study protein kinase A - linked to heart failure

Scientists studying heart cells have devised a new way to visualize and quantify the rise and fall in the activity of a key enzyme linked to heart failure.

8 Aug 2006

Leukemia gene changes genetic packaging

A signaling system involved in many forms of leukemia and lymphoma is more powerful than scientists have thought, exerting control over our genes by affecting whole swaths of chromosomes in global fashion.

6 Aug 2006

Scientists identifiy the way MDM2 protein can trigger the spread of cancer

The protein, MDM2, normally functions to control the activity of a key cancer preventing protein called p53.

25 Jul 2006

New molecular target for obesity

Mice bred without the enzyme MKP-1 are resistant to weight gain despite consuming high fat foods and eating more than control mice, according to a research study published online in Cell Metabolism.

24 Jul 2006

Pomegranate juice helps fight prostate cancer

Drinking an eight ounce glass of pomegranate juice daily increased by nearly four times the period during which PSA levels in men treated for prostate cancer remained stable, a three-year UCLA study has found.

4 Jul 2006

In vitro fertilisation could be causing genetic errors in embryo

The conditions in which embryos are cultured in the laboratory during in vitro fertilisation could be causing genetic errors that are associated with certain developmental syndromes and other abnormalities in growth and development, such as low birth weight.

19 Jun 2006