Cellular Biology News and Research

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Protein controls acid in cells by direct detection of volume changes

A protein responsible for regulating acid levels within cells - and pumping out acid accumulated in cardiac cells after a heart attack - activates in direct response to changes in a cell's volume, according to a new study by researchers at UT Southwestern Medical Center at Dallas.

5 Jul 2004

Molecular biologists find chink in the armor of Candida, the most common human fungal pathogen

Molecular biologists at Rice University have discovered a key defense mechanism that the yeast Candida albicans uses against attack by the human immune system.

26 Jun 2004

New centre of excellence to develop stem cell treatments for diabetes and diseases of the brain

New centre of excellence at the University of Cambridge to develop stem cell treatments for diabetes and diseases of the brain, including Parkinson’s disease and multiple sclerosis.

21 Jun 2004

First license to begin research involving therapeutic cloning

A special licensing committee of the UK Human Fertilization & Embryology Authority (HFEA) met on June 16 in London to decide whether to grant a license to scientists at The Center for Life at Newcastle University.

20 Jun 2004

Possible therapeutic approach to lowering LDL cholesterol and homocysteine levels

Canadian scientists report that mice genetically altered so as to lack either of the two different pathways through which humans, mice, and other animals provide lipids for high density and low density lipoproteins (HDL and LDL) did not appear to suffer any ill effects. But animals from both groups had markedly lower levels of cholesterol in their blood stream.

14 Jun 2004

People with extremely early or extremely late sleep times may suffer from Circadian Rhythm Sleep Disorder

You probably know "night owls," those people not ready to fall asleep until the wee hours of the morning. And, you may also know "larks," those early risers who wake before the sun comes up and are ready for bed right after dinner. People with extremely early or extremely late sleep times may suffer from Circadian Rhythm Sleep Disorder (CRSD).

11 Jun 2004

Bone marrow stem cells exposed to damaged liver tissue quickly convert into healthy liver cells

Bone marrow stem cells, when exposed to damaged liver tissue, can quickly convert into healthy liver cells and help repair the damaged organ, according to new research from the Johns Hopkins Kimmel Cancer Center.

2 Jun 2004

Understanding focal adhesion kinase (FAK) may lead to new cancer treatments

Scientists at the University of North Carolina at Chapel Hill have found an unexpected way to turn off a cellular enzyme involved in the progression of several types of human cancers.

2 Jun 2004

Research laboratory at the forefront of the science of metabolomics

A new $1.8 million research laboratory will catapult Iowa State University to the forefront of the science of metabolomics.

2 Jun 2004

₤16.5 million investment in stem cell research

A ₤16.5 million investment in stem cell research was announced today, 27th May, promising to speed the development of new treatments and cures from the laboratory to the clinic. In total, 57 multidisciplinary research grants have been awarded as part of the new monies allocated via the 2002 Government Spending Review to the UK Research Councils.

27 May 2004

International adult stem cell 'retraining' project starts in Birmingham

An exciting research project to utilise the body's own stem cells to regenerate areas of tissue damage is uniting scientists in Birmingham, London and Ontario, Canada. The University of Birmingham is leading a three year study with long term aims of helping stroke, Parkinsons and diabetes patients.

27 May 2004

Toxoplasma gondii discovery may help fight against malaria

University of North Carolina at Chapel Hill scientists have discovered a protein in the cell wall of parasites that’s crucial to the molecular mechanism allowing them to move between cells, survive and cause disease.

25 May 2004

Researchers to develop a highly sensitive, portable method of detecting bioterror agents like anthrax

Their method uses "Cellular Analysis and Notification of Antigen Risks and Yields" (CANARY) cells, which are immune-system cells engineered to contain a fluorescent protein naturally found in jellyfish. CANARY cells have the immune system's ability to detect specific disease-causing agents, lighting up when they recognize a pathogen.

24 May 2004

Revolutionary self healing bandage that uses the patient's own cells

A revolutionary type of 'self healing' bandage that uses the patient's own cells is being developed. The technique has already been tried successfully on patients with diabetic ulcers and in the long-term could offer a more effective, quicker and cost efficient way of treating many types of slow-healing wounds such as pressure ulcers.

24 May 2004

Are we as crazy as mad cows?

When proteins in our body work properly, we can see, smell, consume and digest food, grow muscle and brain cells. But when these infinitely useful biological building blocks fail, the most pernicious diseases arise. Susan Lindquist has scrutinized the complex origami-like shapes of proteins and come to understand how structural mistakes can lead to a frightening class of neurodegenerative disorders, including “Mad Cow Disease.”

20 May 2004

Natural biological process by which yeast cells dismantle amyloid fibers

Amyloid fibers, those clumps of plaque-like proteins that clog up the brains of Alzheimer's patients, have perplexed scientists with their robust structures. In laboratory experiments, they are able to withstand extreme heat and cold and powerful detergents that cripple most other proteins.

20 May 2004

Cell division can be halted in multiple ways, with implications for cancer

Brown University researchers have found that there are multiple independent ways to stop cell division, a phenomenon that prevents the spread of genetic mutation, which can make cells cancerous. Results of this research, along with an accompanying editorial, were published in the current issue of the journal Molecular Cell.

20 May 2004

Scientists may have figured out how to use stem cells to regenerate lost or injured tissue

In experiments with fruit flies, Johns Hopkins scientists have restored the insect's sperm-making stem cells by triggering cells on the way to becoming sperm to reverse course. The unexpected findings are described in the May 13 issue of Science.

19 May 2004

Closer to understanding the function of a protein linked to an inherited form of the movement disorder dystonia

The protein, torsinA, is defective in patients with DYT1 dystonia, an inherited condition that causes uncontrollable movements in the limbs and torso. Learning what torsinA does could be an important step toward developing a treatment for the disorder.

19 May 2004

Scientists move closer toward treatment for degenerative diseases

Scientists at McGill University's Faculty of Medicine have discovered a key step that will provide new targets for treatments of many degenerative diseases such as Alzheimer's, Cystic Fibrosis and Diabetes.

17 May 2004

Cellular Biology News and Research

Protein controls acid in cells by direct detection of volume changes

Molecular biologists find chink in the armor of Candida, the most common human fungal pathogen

New centre of excellence to develop stem cell treatments for diabetes and diseases of the brain

First license to begin research involving therapeutic cloning

Possible therapeutic approach to lowering LDL cholesterol and homocysteine levels

People with extremely early or extremely late sleep times may suffer from Circadian Rhythm Sleep Disorder

Bone marrow stem cells exposed to damaged liver tissue quickly convert into healthy liver cells

Understanding focal adhesion kinase (FAK) may lead to new cancer treatments

Research laboratory at the forefront of the science of metabolomics

₤16.5 million investment in stem cell research

International adult stem cell 'retraining' project starts in Birmingham

Toxoplasma gondii discovery may help fight against malaria

Researchers to develop a highly sensitive, portable method of detecting bioterror agents like anthrax

Revolutionary self healing bandage that uses the patient's own cells

Are we as crazy as mad cows?

Natural biological process by which yeast cells dismantle amyloid fibers

Cell division can be halted in multiple ways, with implications for cancer

Scientists may have figured out how to use stem cells to regenerate lost or injured tissue

Closer to understanding the function of a protein linked to an inherited form of the movement disorder dystonia

Scientists move closer toward treatment for degenerative diseases

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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