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Data results of NCI-MATCH trial in tumors with DNA mismatch repair deficiencies

Final results are published from an evaluation of 42 patients treated with the immune checkpoint inhibitor nivolumab in the large multi-arm precision medicine trial, NCI-Molecular Analysis for Therapy Choice (NCI-MATCH or EAY131).

20 Dec 2019

Catastrophic macropinocytosis may aid in cancer treatment

In laboratory experiments, a metabolic inhibitor was able to kill a variety of human cancer cells of the skin, breast, lung, cervix and soft tissues through a non-apoptotic route -- catastrophic macropinocytosis.

18 Dec 2019

Nano-sized vesicles released by bacteria may protect against HIV infection

Nano-sized vesicles released by certain bacteria that inhabit the vagina may protect against HIV infection, suggests a study of human cells and tissues by researchers at the National Institutes of Health and the University of Bologna, Italy. Known as extracellular vesicles, these bubble-like particles are produced by many kinds of cells and are thought to transport molecules from one cell to another.

11 Dec 2019

Preterm birth could be spotted early by ultrasound

A new presentation at the 178th Meeting of the Acoustical Society of America in San Diego will report on ultrasound as used in pregnancy, especially with respect to the comparison of two sets of data derived from two separate ultrasound techniques to evaluate cervical changes. The researchers claim that both ultrasound techniques help to estimate the attenuation coefficient of human cervical tissue, and to thus assess changes in it, providing a better picture of the true risk for preterm birth thereby.

4 Dec 2019

Why some sperm swim in circles – it’s a protein defect

A new study published in the journal PNAS shows that some sperm cannot swim straight because they lack a protein called VSP. This motility defect seriously impacts the rates of successful fertilization. In addition, VSP is also found to regulate the amount of calcium that enters the flagellum, the whiplike organelle that propels the sperm towards the waiting ovum or egg. This important discovery may help treat infertility more effectively.

3 Dec 2019

Cochrane review provides information on HPV vaccines and dose schedules in young women, men

New evidence published in the Cochrane Library today provides further information on the benefits and harms of different human papillomavirus vaccines and vaccine schedules in young women and men.

22 Nov 2019

Vaccination against HIV can be counterproductive if it triggers the wrong type of immune response

A discovery could help immunologists design vaccines that are more effective in protecting against HIV infection.

20 Nov 2019

25 years of research to fight cervical cancer

According to the World Health Organization, cervical cancer is the fourth most common type of cancer affecting women worldwide. Currently, early screenings of pre-cancerous tissues and vaccination have proven to be the most effective treatment strategies.

19 Nov 2019

Anal cancer diagnoses and death rates have increased dramatically over the last 15 years

Rates of new anal cancer diagnoses and deaths related to human papillomavirus, the most common sexually transmitted infection, have increased dramatically over the last 15 years, according to researchers at The University of Texas Health Science Center at Houston.

19 Nov 2019

Contraceptive drug effective in preventing and regressing cervical cancer in mice

A new study in The American Journal of Pathology, published by Elsevier, reports that medroxyprogesterone acetate (MPA), the active ingredient in the common contraceptive injection Depo-Provera, was effective in preventing the development of cervical cancer in mice with precancerous lesions.

12 Nov 2019

New light on the essential reproductive role of the clitoris

A new study focuses on the role of the clitoris in females, showing that when it is stimulated, it triggers a wave of changes within the rest of the reproductive tract. The outcome of these changes confers on the clitoris not only recreative but also reproductive importance, according to the studies.

10 Nov 2019

Novel home testing kit for cervical cancer could replace Pap tests

A new method of cervical cancer screening which is designed to be done by women at home could bring down the rates of cervical cancer and associated deaths. The work, presented at the National Cancer Research Institute (NCRI) Conference 2019 in Glasgow, has attracted immense attention because of its feasibility and wide acceptance.

6 Nov 2019

Review: Clitoris is important for reproduction

A recent review published in Clinical Anatomy highlights evidence that the female clitoris is important for reproduction.

6 Nov 2019

Study demonstrates an effective way to predict labor induction

When labor is induced in pregnant women, one in five women will require an emergency cesarean section.

6 Nov 2019

Self-sampling could increase detection of cervical pre-cancer

A non-invasive test to detect cervical pre-cancer could increase participation rates in cervical cancer screening programs.

4 Nov 2019

How does cancer look on day 1? Researchers collaborate to find out

Researchers from Britain and United States are working in collaboration to detect the earliest possible sign of cancer within the body and trace the alterations that lead to full blown cancer. This may help doctors detect cancer even before it is fully formed, the researchers hope.

24 Oct 2019

School-based HPV immunization program dramatically reduces rates of cervical pre-cancer

A school-based human papillomavirus immunization program in British Columbia, Canada, is dramatically reducing rates of cervical pre-cancer in B.C. women, according to a new study.

21 Oct 2019

Hyperbaric oxygen therapy can relieve symptoms and side-effects of radiotherapy

Hyperbaric oxygen therapy can relieve self-reported symptoms and side-effects of radiotherapy against cancer in the pelvic region, a study shows. After 30-40 sessions in a hyperbaric chamber, many patients experienced reductions in bleeding, urinary incontinence, and pain alike.

16 Oct 2019

Closure of women's health clinics linked to lower cervical cancer screening and higher mortality

Following the closure of nearly 100 women's health clinics across the United States from 2010 to 2013, fewer women were screened for cervical cancer, more women were diagnosed with advanced stages of the disease and mortality rates rose.

26 Sep 2019

Papilloma viruses capable of spreading via blood

Human Papilloma Virus or HPV has been known to be transmitted between humans via sexual contact and HPV has been known to be a sexually transmitted disease or STD. The Centers for Disease Control and Prevention (CDC) states that HPV is one of the commonest STDs among humans.

12 Sep 2019