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Genetics of imatinib resistance in acute lymphoblastic leukemia

In the September 15th issue of Genes & Development, Drs. Richard T. Williams, Willem den Besten, and Charles J. Sherr at Howard Hughes Medical Institute, St. Jude Children's Research Hospital in Memphis TN, lend new insights into how an aggressive form of acute lymphoblastic leukemia (ALL) develops, and how sensitivity to the targeted chemotherapeutic drug, imatinib, can be diminished through interactions between tumor cells and the host microenvironment.

30 Aug 2007

Discovery of key link that causes malarial infection in both humans and mosquitoes

As summer temperatures cool in the United States, fewer mosquitoes whir around our tiki torches.

30 Aug 2007

Cramming doesn't work in the long term

When you look back on your school days, doesn't it seem like you studied all the time?

30 Aug 2007

Men more likely than women to choose relationship over career

Men may be more willing than women to sacrifice achievement goals for a romantic relationship, according to a new study by Catherine Mosher of Duke Medical Center and Sharon Danoff-Burg from the University of Albany.

29 Aug 2007

For some being uninsured is a matter of choice

"While it is true that the number of uninsured has grown, it is equally true that the number of people with insurance has continued to grow steadily," said NCPA Senior Fellow Devon Herrick.

29 Aug 2007

Researchers explain evolution of lifespan

Stanford scientists show in a forthcoming paper that traditional mating patterns make men the key to explaining away the "wall of death," an enduring puzzle in the study of human longevity.

29 Aug 2007

Gamma globulin effective treatment for pinkeye

Gamma globulin, a type of antibody isolated from blood samples that used to be routinely given to health care workers and international travelers to protect them from infectious diseases, is a highly effective treatment for pinkeye with little apparent toxicity, according to a study by researchers at the University of Pittsburgh School of Medicine.

29 Aug 2007

St. Jude discovers factors that accelerate resistance to Gleevec targeted therapy in lymphoblastic leukemia

Results of a study by investigators at St. Jude Children's Research Hospital provide strong evidence for why the drug imatinib (Gleevec), which has revolutionized the treatment of chronic myelogenous leukemia (CML), is often unable to prevent relapse of a particularly aggressive form of acute lymphoblastic leukemia (ALL).

29 Aug 2007

Make all school routes 20mph zones, says BMA

All walk to school routes in Wales should be designated 20 mph zones, according to Welsh doctors leaders.

29 Aug 2007

China: The aging giant

China's efforts to control population growth in the present may cause problems for the county's senior citizens in the future.

29 Aug 2007

The travesty of uninsured Americans

U.S. Census Bureau data shows a rise in the number of Americans lacking health insurance. 47 million people did not have health coverage in 2006, up from 44.8 million in 2005.

29 Aug 2007

Gestational diabetes doubles children's risk of obesity

According to the latest research babies born to mothers with untreated gestational diabetes have nearly double the normal risk of becoming obese during childhood.

29 Aug 2007

AIDS Healthcare Foundation names new chief of medicine: Homayoon Khanlou, M.D.

AIDS Healthcare Foundation (AHF) today announced that it is has named Homayoon Khanlou, M.D. as its Chief of Medicine, U.S. Prior to assuming his new role as Chief, Dr. Khanlou served as AHF's Associate Director of Medicine, Regional Medical Director of Western Region while also holding the posts of AHF's Associate Director of Research and the Medical Director and attending physician for the San Fernando Valley and Antelope Valley Healthcare Centers. Dr. Khanlou has also served as Chair of the Pharmacy and Therapeutic Committee at AHF.

28 Aug 2007

Report shows PA hospitals national leaders in health IT adoption, investment

Despite high barriers, Pennsylvania's hospitals have established a leadership position in the adoption of health information technology (IT) as compared to their peers nationwide.

28 Aug 2007

New research findings on Apert's syndrome

Aperts syndrome is a condition caused by a mutation that produces fused fingers and toes, and alters cranial development in affected children.

28 Aug 2007

Higher rates of new asthma among WTC workers

Findings released by the Health Department shed new light on the health effects of exposure to dust and debris among workers who responded to the World Trade Center disaster on September 11, 2001.

28 Aug 2007

ReBuilder Medical Technologies secures license to manufacture electronic molluscum contagiosum treatment system

ReBuilder Medical Technologies, Inc. has announced that it has negotiated an exclusive license from White Hall, Inc. for the micronized, amorphous silver ion technology to treat the highly contagious skin disease, Molluscum Contagiosum.

28 Aug 2007

IDM Pharma receives not approvable letter for Mifamurtide for treatment of osteosarcoma

IDM Pharma, Inc. ( NASDAQ:IDMI ) announced today that it received a not approvable letter from the U.S. Food and Drug Administration (FDA) after completing the review of the new drug application (NDA) for the investigational drug mifamurtide (L-MTP-PE), formerly known as Junovan, for the treatment of non-metastatic osteosarcoma, a rare and often fatal bone tumor that typically affects children and young adults.

28 Aug 2007

New understanding of what makes a major global bacterial infection deadly

Researchers believe they have discovered why a bacterial lung infection is so lethal in the early stages, and it's not what medical authorities had thought, according to research published in the journal Immunity.

28 Aug 2007