Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Only 1 in 4 Americans aged 50-64 regularly take advantage of preventive screenings, says report

Only about 1 in 4 Americans aged 50-64 regularly take advantage of preventive services such as screenings and immunizations, according to a report from the Centers for Disease Control and Prevention in collaboration with AARP and the American Medical Association (AMA).

20 Nov 2009

Scientists anticipate new approaches in drug development to combat prion infection

The regulating protein Srebp2 drives cholesterol formation, which prions need for their propagation, in prion-infected neuronal cells. With these findings, published in the current issue of the Journal of Biological Chemistry, scientists of Helmholtz Zentrum München and Technische Universität München anticipate new approaches in drug development to combat prion infection.

20 Nov 2009

Purchasing prescription drugs in a three-month supply reduce cost of drugs for patients

Purchasing prescription drugs in a three-month supply rather than a one-month supply has long been regarded as a way to reduce the cost of drugs for patients and third-party payers. New research from the University of Chicago quantifies the savings for the first time.

20 Nov 2009

High blood pressure: A major risk factor for stroke and heart disease

Today, Jamieson Laboratories, in partnership with the Victorian Order of Nurses (VON), is holding a one day Blood Pressure Blitz in Toronto's underground PATH system in an effort to educate consumers about the number one risk factor for stroke and a major risk factor of heart disease.

20 Nov 2009

Data from second positive pivotal study of PSD502 for treatment of PE presented

At the annual meeting of the Sexual Medicine Society of North America (SMSNA), Inc. in San Diego, Sciele Pharma, Inc., a Shionogi Company and Plethora Solutions Limited, a wholly owned subsidiary of Plethora Solutions Holdings PLC ("Plethora")., today presented data from its second positive pivotal study of PSD502 for the treatment of premature ejaculation (PE).

20 Nov 2009

Positive results from Sciele Pharma's second pivotal study of PSD502 for the treatment of PE

At the annual meeting of the Sexual Medicine Society of North America, Inc. in San Diego, Sciele Pharma, Inc., a Shionogi Company, and Plethora Solutions Limited, a wholly owned subsidiary of Plethora Solutions Holdings PLC, today presented data from its second positive pivotal study of PSD502 for the treatment of premature ejaculation (PE).

19 Nov 2009

Experts to study how olive oil lowers the level of cytotoxicity in endothelial cells

Experts at Virgen del Rocío Hospital (Seville, Spain) have begun a study on pregnancy preeclampsia on a sample of 30 pregnant women with a view to demonstrating whether or not consumption of olive oil by this population group results in lower levels of cytotoxicity (for example, cholesterol) in endothelial cells (arterial wall cells).

19 Nov 2009

Joint project focuses on finding ways to prevent dementia, including Alzheimer's disease

Every two years, 2,000 senior Group Health patients check in with the Adult Changes in Thought (ACT) study. The joint project between Group Health Research Institute and the University of Washington (UW) focuses on finding ways to delay or prevent dementia, including Alzheimer's disease, and declines in memory and thinking.

19 Nov 2009

Dual niacin-statin therapy improves blood cholesterol levels but does not diminish plaque buildup

The routine prescription of extended-release niacin, a B vitamin (1,500 milligrams daily), in combination with traditional cholesterol-lowering therapy offers no extra benefit in correcting arterial narrowing and diminishing plaque buildup in seniors who already have coronary artery disease, a new vascular imaging study from Johns Hopkins experts shows.

19 Nov 2009

Gene-diet interaction influencing BMI and obesity replicated in three independent studies

Tufts University researchers have identified a gene-diet interaction that appears to influence body weight and have replicated their findings in three independent studies. Men and women carrying the CC genotype demonstrated higher body mass index (BMI) scores and a higher incidence of obesity, but only if they consumed a diet high in saturated fat. These associations were seen in the apolipoprotein A-II gene (APOA2) promoter.

18 Nov 2009

Findings of Merck's anacetrapib phase IIb study presented at the AHA sessions

In a phase IIb study in 589 patients with primary hypercholesterolemia or mixed hyperlipidemia treated with anacetrapib as monotherapy or co-administered with atorvastatin, there were persistent lipid effects in the higher dose arms in both the monotherapy and co-administration treatment groups eight weeks after stopping active therapy with anacetrapib.

18 Nov 2009

CRESTOR reduces major cardiovascular events in women by 46%

A new analysis of the JUPITER trial, released today at the American Heart Association meeting in Orlando, Florida, demonstrates that CRESTOR (rosuvastatin calcium) 20mg reduced first major cardiovascular events by 46%.

18 Nov 2009

Pediatric data for Pfizer's Lipitor submitted to the EMEA

Pfizer Inc announced it has submitted pediatric data for Lipitor® (atorvastatin) to the European Medicines Agency (EMEA). Pfizer has also developed a new chewable form of Lipitor, including a pediatric-appropriate 5 mg dose, which is part of this submission.

18 Nov 2009

Data demonstrate that danger of low levels of HDL is not reduced by statin treatment

Data released today at the American Heart Association (AHA) Scientific Sessions 2009 define the increased risk of heart attacks and cardiovascular disease in patients with low levels of HDL-C (known as "good cholesterol"). The data also determine that statins are unable to significantly impact the heart attack or cardiovascular disease risks associated with low HDL-C.

18 Nov 2009

Combination of night work, overtime and shortened sleep can increase risk of stroke and heart disease

A new study published in the current issue of Archives of Environmental & Occupational Health (vol. 64, No. 3) shows that this combination of night work, overtime and shortened sleep can contribute to the development among police officers of the metabolic syndrome, a combination of unhealthful factors that increase the risk of cardiovascular disease (CVD), primarily heart disease and stroke.

18 Nov 2009

Depression is as much of a risk factor for mortality as smoking, says new study

A study by researchers at the University of Bergen, Norway, and the Institute of Psychiatry (IoP) at King's College London has found that depression is as much of a risk factor for mortality as smoking.

17 Nov 2009

Genzyme and Isis Pharmaceuticals announce phase 3 study data of mipomersen

Genzyme Corp. and Isis Pharmaceuticals Inc. announced that data from the phase 3 study of mipomersen in patients with homozygous familial hypercholesterolemia (hoFH) were presented today at the American Heart Association’s Scientific Sessions.

17 Nov 2009

Health Net’s MA product portfolio offers budget-friendly health plan choices to beneficiaries for 2010

With the kick-off of the Medicare Annual Election Period (AEP) this week, Health Net, Inc. reminds those eligible for Medicare that Health Net’s Medicare Advantage (MA) product portfolio offers a comprehensive range of budget-friendly health plan choices to beneficiaries for 2010.

17 Nov 2009

Upsher-Smith Laboratories publishes results of SLIM Study

Results of the SLIM Study ("Slo-Niacin® and Atorvastatin Treatment of Lipoproteins and Inflammatory Markers in Combined Hyperlipidemia") were recently published in the Journal of Clinical Lipidology.

17 Nov 2009

Trustmark Voluntary Benefit Solutions offers coverage for vaccines including H1N1 to its policyholders

Trustmark Voluntary Benefit Solutions, a leading provider of payroll-deducted voluntary benefits, is now covering vaccines including H1N1 (swine flu).

17 Nov 2009

Cholesterol News and Research

Further Reading

Only 1 in 4 Americans aged 50-64 regularly take advantage of preventive screenings, says report

Scientists anticipate new approaches in drug development to combat prion infection

Purchasing prescription drugs in a three-month supply reduce cost of drugs for patients

High blood pressure: A major risk factor for stroke and heart disease

Data from second positive pivotal study of PSD502 for treatment of PE presented

Positive results from Sciele Pharma's second pivotal study of PSD502 for the treatment of PE

Experts to study how olive oil lowers the level of cytotoxicity in endothelial cells

Joint project focuses on finding ways to prevent dementia, including Alzheimer's disease

Dual niacin-statin therapy improves blood cholesterol levels but does not diminish plaque buildup

Gene-diet interaction influencing BMI and obesity replicated in three independent studies

Findings of Merck's anacetrapib phase IIb study presented at the AHA sessions

CRESTOR reduces major cardiovascular events in women by 46%

Pediatric data for Pfizer's Lipitor submitted to the EMEA

Data demonstrate that danger of low levels of HDL is not reduced by statin treatment

Combination of night work, overtime and shortened sleep can increase risk of stroke and heart disease

Depression is as much of a risk factor for mortality as smoking, says new study

Genzyme and Isis Pharmaceuticals announce phase 3 study data of mipomersen

Health Net’s MA product portfolio offers budget-friendly health plan choices to beneficiaries for 2010

Upsher-Smith Laboratories publishes results of SLIM Study

Trustmark Voluntary Benefit Solutions offers coverage for vaccines including H1N1 to its policyholders

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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