Chromosome 4 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 4, one copy inherited from each parent, form one of the pairs. Chromosome 4 spans more than 191 million DNA building blocks (base pairs) and represents more than 6 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 4 likely contains between 1,300 and 1,600 genes.

Genes on chromosome 4 are among the estimated 20,000 to 25,000 total genes in the human genome.
Human protein may help prevent H1N1 infection

Human protein may help prevent H1N1 infection

Landmark study provides new insight into congenital heart defects

Landmark study provides new insight into congenital heart defects

Genes work together by huddling in clusters inside nucleus, research reveals

Genes work together by huddling in clusters inside nucleus, research reveals

Results from five new studies on Genomic Health's Oncotype DX breast cancer test announced

Results from five new studies on Genomic Health's Oncotype DX breast cancer test announced

Study may help in treating sex differentiation disorders in children

Study may help in treating sex differentiation disorders in children

Researchers discover new explanation for differences in severity of mental illness in males

Researchers discover new explanation for differences in severity of mental illness in males

Tasigna demonstrates greater efficacy over Gleevec in chronic Ph+ CML patients

Tasigna demonstrates greater efficacy over Gleevec in chronic Ph+ CML patients

Enzo Biochem and Ikonisys sign agreement to market molecular-based cervical cancer test

Enzo Biochem and Ikonisys sign agreement to market molecular-based cervical cancer test

Clinical trial results demonstrate greater efficacy of nilotinib over imatinib for Ph+ CML

Clinical trial results demonstrate greater efficacy of nilotinib over imatinib for Ph+ CML

CML patients on nilotinib or dasatinib drug achieve better response than imatinib drug

CML patients on nilotinib or dasatinib drug achieve better response than imatinib drug

Positive data from ARIAD Pharmaceuticals' ongoing AP24534 study in advanced hematological cancer patients

Positive data from ARIAD Pharmaceuticals' ongoing AP24534 study in advanced hematological cancer patients

New genetic approach may hold promise for sickle cell disease

New genetic approach may hold promise for sickle cell disease

Animal study demonstrates how whole chromosome changes cause cancer

Animal study demonstrates how whole chromosome changes cause cancer

Phase II clinical trial results reveal positive effects of omacetaxine against CML

Phase II clinical trial results reveal positive effects of omacetaxine against CML

New findings may yield more effective therapies for infants with blood cancer

New findings may yield more effective therapies for infants with blood cancer

New study reveals genetic alteration can lead to severe childhood obesity

New study reveals genetic alteration can lead to severe childhood obesity

New treatment options for leukemia and myeloproliferative disorders introduced

New treatment options for leukemia and myeloproliferative disorders introduced

IMF to stage presentation on multiple myeloma at ASH annual meeting

IMF to stage presentation on multiple myeloma at ASH annual meeting

Researchers discover mechanism that explains how chromosomal translocations are not random

Researchers discover mechanism that explains how chromosomal translocations are not random

More than 80 abstracts highlighting Bristol-Myers Squibb's oncology compound to be presented

More than 80 abstracts highlighting Bristol-Myers Squibb's oncology compound to be presented

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