Chromosome 4 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 4, one copy inherited from each parent, form one of the pairs. Chromosome 4 spans more than 191 million DNA building blocks (base pairs) and represents more than 6 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 4 likely contains between 1,300 and 1,600 genes.

Genes on chromosome 4 are among the estimated 20,000 to 25,000 total genes in the human genome.
Nitric oxide could one day help women in their 30s and 40s remain fertile longer

Nitric oxide could one day help women in their 30s and 40s remain fertile longer

Significant advance in the study of small ribonucleic acids

Significant advance in the study of small ribonucleic acids

Overall genome landscape between chimps and humans can be attributed to large segmental duplications

Overall genome landscape between chimps and humans can be attributed to large segmental duplications

Significant advance in the study of small ribonucleic acids

Significant advance in the study of small ribonucleic acids

Toluidine blue dye reveals oral cancers

Toluidine blue dye reveals oral cancers

Human Y chromosome stays intact while chimp Y loses genes

Human Y chromosome stays intact while chimp Y loses genes

Compound called GRN163L blocks lung cancer

Compound called GRN163L blocks lung cancer

Discovery of a potential oncogene in ovarian cancer

Discovery of a potential oncogene in ovarian cancer

First proof of how the rare disorder Fanconi anemia causes chromosomal instability

First proof of how the rare disorder Fanconi anemia causes chromosomal instability

Researchers have discovered a gene linked to age-related maculopathy

Researchers have discovered a gene linked to age-related maculopathy

Placental tissue could feasibly provide an abundant source of cells with the same potential to treat diseases as embryonic stem cells

Placental tissue could feasibly provide an abundant source of cells with the same potential to treat diseases as embryonic stem cells

First evidence that complex genetic interactions account for autism risk

First evidence that complex genetic interactions account for autism risk

Customized gene chip offers clues to prognosis in cases of neuroblastoma

Customized gene chip offers clues to prognosis in cases of neuroblastoma

Customized gene chip will offer clues to prognosis in cases of neuroblastoma

Customized gene chip will offer clues to prognosis in cases of neuroblastoma

Exposure to second-hand smoke during pregnancy can be just as detrimental to a developing fetus as primary exposure through maternal smoking

Exposure to second-hand smoke during pregnancy can be just as detrimental to a developing fetus as primary exposure through maternal smoking

Multi-species genome comparison sheds new light on evolutionary processes

Multi-species genome comparison sheds new light on evolutionary processes

Scientists have identified the first genetic mutations that cause the aorta to widen, tear and rupture

Scientists have identified the first genetic mutations that cause the aorta to widen, tear and rupture

Gene that regulates normal embryonic development is found at high levels in virtually all forms of breast cancer

Gene that regulates normal embryonic development is found at high levels in virtually all forms of breast cancer

New insight into age-related macular degeneration

New insight into age-related macular degeneration

Multiple rare mutations within a single gene may increase risk for autism

Multiple rare mutations within a single gene may increase risk for autism

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