Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 6, one copy inherited from each parent, form one of the pairs. Chromosome 6 spans about 171 million base pairs (the building blocks of DNA) and represents between 5.5 percent and 6 percent of the total DNA in cells.
Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 6 likely contains between 1,100 and 1,600 genes.
Genes on chromosome 6 are among the estimated 20,000 to 25,000 total genes in the human genome.
Variants in a gene of the human immune system cause men and women to have different vulnerabilities to the autoimmune diseases lupus and Sjögren's syndrome, according to findings published in the journal Nature.
When an actor is unable to perform in the theatre, an understudy--ideally one with some practice in the role--can take her place on stage.
The autoimmune disease lupus, which can cause fatigue, a facial rash, and joint pain, strikes females far more often than males. Eight-five percent of people with lupus are female, and their second X chromosome seems partly to blame.
Low levels of oxygen in the womb - which can be caused by smoking or conditions such as pre-eclampsia - may cause problems with fertility later in life, a study carried out in rats suggests.
Scientists at Johns Hopkins say they have found that people born with abnormally short chromosome endcaps, or telomeres, have immune system cells that age and die prematurely.
Researchers have identified a protein critical for the survival of a particular type of tumor cell, according to a study published today in eLife.
Researchers from INRA, CIRAD, CEA, the University of Montpellier, and Chicago and Vanderbilt Universities in the United States have developed an innovative method for analyzing the genome of the Wolbachia bacterium.
Genetic mutations that drive the development of a common type of childhood leukemia can be traced back to errors by the immune system during the production of antibodies.
Female birds age more slowly and live longer when they have help raising their offspring, according to new research from the University of East Anglia.
Chemistry researchers at Oregon State University have patented a method for making anti-leukemia compounds that until now have only been available via an Asian tree that produces them.
As part of MIT's continued mission to help build a better world, the Institute announced the creation of the Alana Down Syndrome Center, an innovative new research endeavor, technology development initiative, and fellowship program launched with a $28.6 million gift from Alana Foundation, a nonprofit organization started by Ana Lucia Villela of São Paulo, Brazil.
In today's life, we often encounter situations when the organism's functions are overstrained, and the action of extreme factors causes the development of a stress response.
By applying gene analysis to individual cells from early mouse embryos, researchers at Karolinska Institutet in Sweden have discovered previously unknown cellular stages of fetal development from fertilized egg to living being. The study is published in the scientific journal Cell Reports.
Radiation immediately following surgery in children with ependymoma, the third most common pediatric brain tumor, can nearly triple survival.
Not every embryo contains 46 perfect chromosomes. Some have more, others have fewer. The result is a common abnormality known as aneuploidy, which occurs in as many as 80 percent of human embryos.
Doctors report on a woman who gave birth to semi-identical twins in 2014. This is the second time this is known to have occurred after the first case in 2007.
Chromosomes, each containing hundreds or thousands of genes, act like a detailed instruction manual for how cells should develop and behave.
By sequencing the entire genomes of tumor cells from six people with a rare cancer of the nose and sinus cavity, Johns Hopkins researchers report they unexpectedly found the same genetic change¾one in a gene involved in muscle formation¾in five of the tumors.
Researchers from the University of Copenhagen have identified a specific mechanism that protects our cells from natural DNA errors - an 'enemy within' - which could permanently damage our genetic code and lead to diseases such as cancer.
A team of biologists has uncovered a mechanism that determines faithful inheritance of short chromosomes during the reproductive process.