Cilia News and Research

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New study shows how sounds are amplified in the inner ear

St. Jude Children's Research Hospital investigators have found that an electrically powered amplification mechanism in the cochlea of the ear is critical to the acute hearing of humans and other mammals. The findings will enable better understanding of how hearing loss can result from malfunction of this amplification machinery due to genetic mutation or overdose of drugs such as aspirin.

7 May 2008

Genetic research unveils common origins for distinct clinical diagnoses

Researchers at Johns Hopkins have discovered that two clinically different inherited syndromes are in fact variations of the same disorder.

10 Mar 2008

Researchers spearhead key genome initiative

The complete collection of genes - the genome - of a moss has been sequenced, providing scientists an important evolutionary link between single-celled algae and flowering plants.

17 Dec 2007

New role discovered for cilia

Johns Hopkins researchers and colleagues have found a previously unrecognized role for tiny hair-like cell structures known as cilia: They help form our sense of touch.

22 Oct 2007

Chlamydomonas reinhardtii genome holds clues for renewable energy, the environment and human health

University of Minnesota researchers contributed to a national effort to sequence the genome of an ancient, one-celled organism that will help advance research in a broad range of areas, from biofuels to restoring the environment to understanding a variety of human diseases.

12 Oct 2007

New bioengineered antimicrobials help cystic fibrosis patients breathe easier

By better understanding how antimicrobials bind and thereby get inactivated in the mucus of air passages, researchers at the University of Illinois may have found a way to help cystic fibrosis patients fight off deadly infections.

25 Sep 2007

New understanding of immune infertility

Most of us have never heard of immune infertility, yet it prevents many prospective parents from conceiving. Immune infertility is one of 80 autoimmune disorders, a group that includes better-known diseases like Multiple Sclerosis and Type 1 Diabetes.

13 Sep 2007

New discovery helps explain the mechanics of hearing

A 30-year scientific debate about how specialized cells in the inner ear amplify sound in mammals appears to have been settled more in favor of bouncing cell bodies rather than vibrating, hair-like cilia, according to St. Jude investigators.

28 Aug 2007

Saline for chronic rhinosinusitis

Spraying salty water (saline) into your nose can help reduce the symptoms of pain and congestion that accompany long-term infections of the nasal passages, a Cochrane Systematic Review has concluded.

18 Jul 2007

Link between ciliary signaling and cancer

Submarines have periscopes. Insects have antennae. And increasingly, biologists are finding that most normal vertebrate cells have cilia, small hair-like structures that protrude like antennae into the surrounding environment to detect signals that control cell growth.

29 Jun 2007

Cilia research may help find cure for inherited eye diseases

Researchers at the University of Pennsylvania School of Medicine have identified proteins in the rod and cones of the eye that could lead to the discovery of the genetic causes of a host of inherited eye diseases.

23 Jun 2007

New genetic cause for Joubert syndrome

An international study by researchers at Seattle Children?s Hospital Research Institute, the University of Washington School of Medicine, and Radboud University in Nijmegen, Netherlands has identified a new genetic cause for Joubert syndrome (JS).

15 Jun 2007

Thirteenth gene linked to Leber's congenital amaurosis

An international research team has discovered a gene that, when mutated, causes one of the most common forms of inherited blindness in babies.

14 Jun 2007

Primary ciliary dyskinesia linked to heterotaxy

The same genetic defect that causes a rare respiratory disease may also lead to some types of congenital heart disease, according to a study from the University of North Carolina at Chapel Hill School of Medicine.

14 Jun 2007

Chinese herb Lei Gong Teng stops formation of cysts in polycystic kidney disease in lab

Using a compound from a centuries-old Chinese traditional medicine, Yale University researcher Dr. Craig Crews has been able to prevent the formation of kidney-destroying cysts in a mouse model of polycystic kidney disease.

30 Apr 2007

Novel two-step mechanism ensures that all cilia beat in unison

Cilia, tiny hair-like structures that propel mucus out of airways, have to agree on the direction of the fluid flow to get things moving. Researchers at the Salk Institute for Biological Studies discovered a novel two-step mechanism that ensures that all cilia beat in unison.

24 Apr 2007

Newborns with respiratory distress should be evaluated for primary ciliary dyskinesia

Reviewing published reports, Ferkol and Margaret Leigh, M.D., professor of pediatrics at the University of North Carolina at Chapel Hill (UNC), found that neonatal respiratory distress was a common clinical symptom of PCD, a chronic airway disease that affects about 1 in 15,000 children.

20 Feb 2007