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Elevated levels of chronic stress hormones may promote EGFR inhibitor resistance in NSCLC patients

Elevated levels of chronic stress hormones, such as those produced by psychological distress, may promote resistance to drugs commonly used to treat lung cancer patients with EGFR mutations, according to new research from The University of Texas MD Anderson Cancer Center.

9 Nov 2017

Study characterizes hypertensive population with excess weight or obesity and sedentary habits

For the last seven years, researchers in the UPV/EHU's Department of Physical and Sports Education have been studying the hypertensive population with excess weight/obesity and sedentary habits. In a recent publication, this group has determined the state of health of this population through various key physical, physiological, clinical and nutritional markers and has separated them by sex and physical condition.

28 Oct 2017

Study could pave way for more effective cancer therapies

Many tumors possess mechanisms to avoid destruction by the immune system. For instance, they misuse the natural "brakes" in the immune defense mechanism, which normally prevent an excessive immune response. Researchers at the University of Bonn have now been able to take off one of these brakes.

17 Oct 2017

New study uncovers 13 previously-unknown genetic risk variants for restless legs syndrome

A new study into the genetics underlying restless legs syndrome has identified 13 previously-unknown genetic risk variants, while helping inform potential new treatment options for the condition.

13 Oct 2017

Highly elastic surgical glue quickly seals wounds without need for staples or sutures

A highly elastic and adhesive surgical glue that quickly seals wounds without the need for common staples or sutures could transform how surgeries are performed.

4 Oct 2017

Rapid, sensitive genetic test successfully detects some aggressive types of pancreatic cancer

A genetic test developed at UPMC proved highly sensitive at determining which pancreatic cysts are most likely to be associated with one of the most aggressive types of pancreatic cancer, UPMC and University of Pittsburgh School of Medicine scientists reported in Gut, the journal of the British Society of Gastroenterology.

3 Oct 2017

Novel compounds found to be highly effective in preventing transmission of malaria parasites

Significant headway has been made in controlling malaria. However, two vexing problems remain: currently available treatments are unable to block transmission of the parasite that causes the disease, and the parasite often becomes resistant to drugs.

7 Sep 2017

New method of genetic testing leads to successful targeting of MET fusion in lung cancer

There are many ways a gene can be altered and there are many genes that, when altered, can cause cancer. Testing individually for each possible alteration in every cancer-related gene is not feasible as it would require hundreds of individual tests and many, many thousands of dollars.

31 Aug 2017

New antibodies may halt key pathological mechanisms across several neurological diseases

A new kind of antibody targets a feature shared by proteins thought to cause the most damage in Alzheimer's disease, Parkinson's disease, and related conditions, creating potential for a unified treatment approach.

29 Aug 2017

Biologic substance APOSEC shows promise for healing dermal wounds

APOSEC is a substance obtained from white blood corpuscles and was developed by a research group led by thoracic surgeon Hendrik Jan Ankersmit, Head of the Christian Doppler Laboratory for Cardiac and Thoracic Diagnosis and Regeneration at MedUni Vienna.

3 Aug 2017

US FDA approves MRI especially for newborns

The U.S. Food and Drug Administration yesterday approved the first magnetic resonance imaging (MRI) device that can be specifically used in neonates or newborn babies. These MRI devices would be used for imaging of the brains and head in neonates who are admitted to the neonatal intensive care units (NICU) where they are necessary.

20 Jul 2017

FDA clears first MRI device for neonatal brain and head imaging

Today, the U.S. Food and Drug Administration cleared the first magnetic resonance imaging device specifically for neonatal brain and head imaging in neonatal intensive care units.

20 Jul 2017

Researchers uncover new mechanism that promotes growth of blood vessels in tumors

Cancer cells have an enormous need for oxygen and nutrients. Therefore, growing tumors rely on the simultaneous growth of capillaries, the fine branching blood vessels that form a supply network for them.

18 Jul 2017

NIH researchers show how investigational drug works against rare, fatal genetic disease

Scientists have demonstrated how an investigational drug works against a rare, fatal genetic disease, Niemann-Pick type C1 (NPC1).

17 Jul 2017

Scientists positively influence immune response in viral and bacterial co-infection

Researchers from Charité - Universitätsmedizin Berlin were able to positively influence the immune response in severe viral and bacterial co-infection.

13 Jul 2017

New single probe method provides PCR-free detection of microRNA linked to liver toxicity

Quanterix Corporation, a company digitizing biomarker analysis with the goal of advancing the science of precision health, and DestiNA Genomics Ltd, a manufacturer of patented reagents for nucleic acid detection, today announced that PLOS ONE has published a proof-of-concept single probe method for detecting microRNA biomarkers associated with liver toxicity.

6 Jul 2017

Dysfunctional microglia cells contribute to loss of synapses in Alzheimer's disease

Similar to other neurodegenerative disorders, Alzheimer's is a disease in which the cognitive abilities of afflicted persons continuously worsen.

30 Jun 2017

Newly discovered antibiotic could help treat drug-resistant tuberculosis

A newly discovered antibiotic, produced by bacteria from a cystic fibrosis patient, could be used to treat cases of drug-resistant tuberculosis (TB). This is the finding of a team of scientists from Cardiff University’s School of Biosciences and the University of Warwick.

24 Jun 2017

Grape-based compounds could pave way for new treatments to prevent colon cancer

Compounds from grapes may kill colon cancer stem cells both in a petri dish and in mice, according to a team of researchers.

19 Jun 2017

Researchers working towards developing novel stem cell approaches for glaucoma

There is great interest among glaucoma patients, scientists and doctors alike, in discovering regenerative therapies for the optic nerve and translating them from the laboratory to the clinic -; and stem cell therapy is one of several promising approaches being studied.

16 Jun 2017