Clinical Trial News and Research

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Race influences participation in clinical trials

Caucasian and non-Caucasian cancer patients are equally interested in learning about clinical trials. However, non-Caucasian patients are less likely to enroll in a trial unless the chances are high that it would benefit them

4 Oct 2004

Male smokers needed for study to investigate new method of improving selenium intake

Around 200 men – including men who smoke – are being sought by researchers in Adelaide, South Australia to take part in a new study aimed at preventing cancer and other health problems.

30 Sep 2004

Studies confirm that chronic kidney disease independently increases the risk of developing cardiovascular disease

A pair of new epidemiology studies confirms that chronic kidney disease independently increases the risk of developing cardiovascular disease, even among people with early kidney disease and after considering other risk factors such as diabetes, hypertension and high cholesterol.

29 Sep 2004

Draft Medicare plan to cover implantable defibrillators

The Centers for Medicare & Medicaid Services (CMS) today proposed to expand coverage of implantable cardioverter defibrillators (ICDs), a move expected to save thousands of lives a year.

29 Sep 2004

$16 million investment in minute wireless implant technology

Remon Medical Technologies a privately held medical device company, today announced that it has raised $16 million in the initial close of a Series C financing.

23 Sep 2004

New combination of drugs results in fewer incidences of rejection in liver transplant patients

“The big advantage [of this combination of drugs] is that the incidence of rejection is significantly decreased,” he says. “These results could change the standard of care for liver transplant recipients.”

23 Sep 2004

FDA proposal on antidepressants is premature and may be counterproductive

The recent FDA proposal to force antidepressants to carry warnings about increased suicide risk is the subject of a pair of articles by leading experts in The Annals of Pharmacotherapy.

23 Sep 2004

Study on the long-term health effects associated with silicone breast implants

It is estimated that between 1.5 million and 2 million women in this country have had breast implants since they first appeared on the market in 1962.

23 Sep 2004

Acupuncture more effective at reducing nausea and vomiting after major breast surgery than the leading medication

The researchers also found that patients who underwent the 5,000-year-old Chinese practice reported decreased postoperative pain and increased satisfaction with their postoperative recovery. In conducting the trial, the researchers also demonstrated that the pressure point they stimulated possesses previously unknown pain-killing properties.

22 Sep 2004

Bonviva, to treat osteoporosis, submitted for marketing authorisation in Europe

Roche and GlaxoSmithKline announced today the submission of a Marketing Authorisation Application to the European authorities for a novel, once-monthly oral formulation of their new bisphosphonate, Bonviva (ibandronate), for the treatment of postmenopausal osteoporosis.

20 Sep 2004

Immunoglobulins may help patients with Alzheimer’s

Immunoglobulins which are already being used to treat multiple sclerosis may also be able to help patients with Alzheimer’s. This, at least, is the finding of a pilot study on five patients at the University of Bonn.

20 Sep 2004

Titanium rib becomes 1st new FDA-approved spine deformity treatment in 40 years

The Vertical Expandable Prosthetic Titanium Rib (VEPTR), a device that has saved the lives of 300 infants and young children who otherwise would have died from lack of breath, has been approved by the U.S. Food and Drug Administration (FDA).

16 Sep 2004

Celacade shown to reduce risk of death and hospitalization in patients with advanced chronic heart failure

Vasogen has announced that comprehensive results from the Company's phase II trial of Celacade (immune modulation therapy) in advanced chronic heart failure patients were published in the September 15 issue of the Journal of the American College of Cardiology (JACC).

16 Sep 2004

Drug combo may have a greater impact on cancer development

Cancer researchers have long suggested that new targeted drugs may work best when paired with other therapies. In a new study published today in Cancer Research, scientists have taken some of the first steps to demonstrate this synergy in mouse and cell line models.

16 Sep 2004

Cancer drug effective at treating lupus

A drug now used to treat a type of cancer appears to be very effective at treating lupus, with just one injection easing symptoms in several patients for a year or more.

16 Sep 2004

Cancer drug may reduce kidney disease in lupus

A drug that is already being tested as an anticancer agent, especially in lymphoma, may also reduce the kidney disease that is a result of systemic lupus, according to a researcher at Wake Forest University Baptist Medical Center.

10 Sep 2004

International Committee of Medical Journal Editors will require registration of clinical trials for publication

The International Committee of Medical Journal Editors (ICMJE) issued a statement today that the 11 member journals will require, as a condition of consideration for publication, registration in a public trials registry for clinical studies involving human patients.

8 Sep 2004

Study shows that naturopathic medicine helps women experiencing jaw pains

A study involving a painful jaw disorder and the role of naturopathic medicine demonstrates how this holistic approach to care can empower patients to improve their own health.

8 Sep 2004

Gene therapy holds much promise for treating aggressive human superficial bladder cancer

Gene therapy that causes the bladder to act like a “bioreactor” to produce and secrete the anti-cancer agent interferon-alpha has shown dramatic benefits in preclinical tests, say researchers at The University of Texas M. D. Anderson Cancer Center.

8 Sep 2004

Phase I clinical trial of new drug for severe asthma

Cambridge Antibody Technology today announced that it is starting a Phase I clinical trial of CAT-354, a human anti-IL-13 monoclonal antibody, which is a potential treatment for severe asthma, following recent approval from the Medicines and Healthcare products Regulatory Agency (MHRA).

8 Sep 2004