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Novel three-drug combo shows promise in advanced HER2-negative breast cancer treatment

A novel three-drug combination achieved notable responses in patients with advanced HER2-negative breast cancer, according to new research directed by investigators from the Johns Hopkins Kimmel Cancer Center.

14 Feb 2024

Routine change of gloves and instruments is cost-effective and reduces surgical site infections

Surgeons who routinely change surgical gloves and instruments are incurring similar costs to those using the same equipment, a new study has found.

14 Feb 2024

Revvity Signals Software unveils Signals Clinical solution to accelerate critical clinical trial insights and data-driven decisions

Today, Revvity, Inc. announced that its software and informatics division, Revvity Signals, is unveiling the Signals Clinical™ solution, a software-as-a-service (SaaS), end-to-end clinical data science platform designed to centralize all clinical trial data, providing fast, actionable insights for quicker clinical decisions and accelerated market delivery of therapeutics.

From Revvity 14 Feb 2024

Mediterranean and vegetarian diets boost heart health by improving novel CVD markers

Study reveals that both lacto-ovo vegetarian and Mediterranean diets positively impact apolipoprotein levels and cardiovascular disease risk factors, with Mediterranean diet showing a more substantial effect on apolipoprotein levels, particularly in women and older individuals with fewer CVD risk factors.

13 Feb 2024

Novel protocol developed to rapidly diagnose eye stroke and expedite care

Ophthalmologists at New York Eye and Ear Infirmary of Mount Sinai (NYEE) have created a novel protocol to rapidly diagnose eye stroke and expedite care to prevent irreversible vision loss.

13 Feb 2024

Therapist-guided digital therapy reduces distress in people with long-term physical health conditions

A therapist-guided digital cognitive behavioural therapy reduced distress in 89 per cent of participants living with long-term physical health conditions, a new King's College London study finds.

13 Feb 2024

Pre-pandemic exercise tied to lower odds of COVID-19 infection and hospitalization

A cohort study of older adults found that those who followed recommended exercise guidelines before the pandemic had significantly lower odds of being infected or hospitalized from COVID-19 than those who did not follow guidelines.

13 Feb 2024

Daily aspirin linked to higher mortality in older adults, study finds

A study from the ASPREE clinical trial found that daily aspirin intake in adults over 70 did not increase disability-free survival and was associated with higher all-cause mortality, primarily due to cancer-related deaths.

12 Feb 2024

Promising new CMV vaccine shows stronger immune response

An experimental mRNA vaccine against human cytomegalovirus (CMV), a common virus that can infect babies during pregnancy, elicited some of the most promising immune responses to date of any CMV vaccine candidate, according to a study by Weill Cornell Medicine investigators.

12 Feb 2024

Study uncovers missing piece in the complex nerve-network needed for left-right turns

Have you ever wondered what happens in the brain when we move to the right or left? Most people don't; they just do it without thinking about it. But this simple movement is actually controlled by a complex process.

12 Feb 2024

Blocking artery plus surgery offers hope for reducing reoperations in brain hematoma patients

Injection of a substance to block an artery feeding the dura (protective sack around the brain) along with surgery to remove pooled blood reduced the risk that patients will require repeat surgery compared to surgical drainage alone, according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2024.

9 Feb 2024

Nutritional epigenetics education reduces ultra-processed food intake in parents of children with autism and ADHD

In a recent publication released by PubMed, American scientists led by Dr. Dufault at the Food Ingredient and Health Research Institute, reported the results of a clinical trial in which parents who received nutritional epigenetics education significantly reduced their consumption of ultra-processed foods while increasing their intake of whole and/or organic foods.

9 Feb 2024

Scientists develop safer CAR T-cell strategy for treating lymphomas

In the treatment of aggressive lymphomas and blood cancer (leukaemia), so-called chimeric antigen receptor T cells (CAR T cells) are increasingly being used.

9 Feb 2024

Selective androgen receptor modulator has anti-tumor effects in ER-positive breast cancer patients

A research paper published today (8 February 2024) in The Lancet Oncology demonstrates that the drug enobosarm, a selective androgen receptor modulator which stimulates the male sex hormone receptor has anti-tumour effects in estrogen receptor positive breast cancer patients.

8 Feb 2024

Stroke patients see lower death rates with AI-guided treatment

Ischemic stroke survivors who received care recommendations from an artificial intelligence (AI)-based system had fewer recurrent strokes, heart attacks or vascular death within three months, compared to people whose stroke treatment was not guided by AI tools, according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2024.

8 Feb 2024

Hope for relapsed myeloma: Preclinical and clinical evidence for ruxolitinib's efficacy

A new research perspective was published in Oncotarget's Volume 15 on February 5, 2024, entitled, "Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma."

8 Feb 2024

Flat positioning may give stroke patients an edge before surgery

Positioning patients with large vessel ischemic (clot-caused) stroke with their heads flat (0-degrees) before surgery to remove the blood clot resulted in significant improvements in neurological function, compared to patients whose heads were elevated (at a 30-degree angle), according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2024.

8 Feb 2024

NCCN publishes first-ever treatment recommendations pertaining to neuroblastoma

The National Comprehensive Cancer Network (NCCN)-;an alliance of leading cancer centers-;today published its first ever set of treatment recommendations pertaining to neuroblastoma.

8 Feb 2024

Study explores traditional Atlantic diets as a potential solution for diet-related diseases and environmental sustainability

Researchers from Spain investigated the effect of a traditional Atlantic diet on health and the environment.

8 Feb 2024

Combining clot busters and blood thinners shows no advantage for people with ischemic strokes

Giving blood thinners in addition to clot-busting medications to people with ischemic strokes (clot-caused strokes) did not improve their outcomes 90 days later, according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2024.

7 Feb 2024

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Clinical Trial News and Research

Novel three-drug combo shows promise in advanced HER2-negative breast cancer treatment

Routine change of gloves and instruments is cost-effective and reduces surgical site infections

Revvity Signals Software unveils Signals Clinical solution to accelerate critical clinical trial insights and data-driven decisions

Mediterranean and vegetarian diets boost heart health by improving novel CVD markers

Novel protocol developed to rapidly diagnose eye stroke and expedite care

Therapist-guided digital therapy reduces distress in people with long-term physical health conditions

Pre-pandemic exercise tied to lower odds of COVID-19 infection and hospitalization

Daily aspirin linked to higher mortality in older adults, study finds

Promising new CMV vaccine shows stronger immune response

Study uncovers missing piece in the complex nerve-network needed for left-right turns

Blocking artery plus surgery offers hope for reducing reoperations in brain hematoma patients

Nutritional epigenetics education reduces ultra-processed food intake in parents of children with autism and ADHD

Scientists develop safer CAR T-cell strategy for treating lymphomas

Selective androgen receptor modulator has anti-tumor effects in ER-positive breast cancer patients

Stroke patients see lower death rates with AI-guided treatment

Hope for relapsed myeloma: Preclinical and clinical evidence for ruxolitinib's efficacy

Flat positioning may give stroke patients an edge before surgery

NCCN publishes first-ever treatment recommendations pertaining to neuroblastoma

Study explores traditional Atlantic diets as a potential solution for diet-related diseases and environmental sustainability

Combining clot busters and blood thinners shows no advantage for people with ischemic strokes

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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