Clinical Trial News and Research

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Reducing unnecessary testing or treatments in older patients

When a doctor ordered a routine prostate screening for an 80-year-old man -; as doctors often do -; a dramatic yellow alert popped up on the electronic health record with dire warnings.

7 Feb 2024

AMG 133 (maridebart cafraglutide) weight loss drug shows promise in early trial

AMG 133, an engineered bispecific molecule, demonstrated significant weight loss with a favorable safety profile in a phase 1 clinical trial, offering a promising new treatment option for obesity.

7 Feb 2024

Snacking on pistachios may combat metabolic syndrome risk without weight gain

More than half of Americans do not currently meet the daily recommendation of 5–7 ounce equivalents of nuts and seeds per week.

7 Feb 2024

Experimental mRNA vaccine against CMV elicits promising immune responses

An experimental mRNA vaccine against human cytomegalovirus (CMV), a common virus that can infect babies during pregnancy, elicited some of the most promising immune responses to date of any CMV vaccine candidate, according to a study by Weill Cornell Medicine investigators.

7 Feb 2024

New link between stress, immune system, and depression discovered

Chronic stress affects the immune system and the brain. UZH researchers now show that a particular enzyme found in cells of the immune system enters the brain under stress.

7 Feb 2024

AI helps predict antidepressant response in a week

In patients with major depression disorder it is, thanks to use of artificial intelligence, now possible to predict within a week whether an antidepressant will work.

7 Feb 2024

Eleven stroke researchers to be recognized during the 2024 International Stroke Conference

Eleven scientists leading the way in stroke research will be recognized during the American Stroke Association's International Stroke Conference 2024 for their exceptional professional achievements.

6 Feb 2024

New cell therapy shows promise for critically ill COVID-19 patients with ARDS

Promising trial results indicate that a new type of cell therapy could improve the prognosis of those who are critically ill with acute respiratory distress syndrome (ARDS) resulting from severe Covid-19.

6 Feb 2024

Doppler ultrasound detects placental issues in small babies, study finds

A Doppler ultrasound that measures the blood flow of small unborn babies can reveal whether or not the placenta is working properly. In case of repeated deviations from these Doppler measurements, additional monitoring of the unborn baby is necessary.

5 Feb 2024

New weight loss drug may be an effective strategy for preventing or treating high blood pressure

The new weight loss medication tirzepatide significantly lowered the systolic blood pressure (the top number in a blood pressure reading) for nearly 500 adults with obesity who took the medication for about eight months, according to new research published today in Hypertension, an American Heart Association journal.

5 Feb 2024

First gene therapy trial aims to restore hearing in children

The aim of this clinical trial, which has just received approval in France, is to assess the safety and efficacy of a new gene therapy drug in children aged between 6 and 31 months with profound hearing loss.

5 Feb 2024

PI3K/AKT and MEK/ERK pathways targeted in new therapy for docetaxel-resistant prostate cancer

A team of researchers from the Badalona Applied Research Group in Oncology (B·ARGO) and the Urologic Tumours Unit of the Institut Català d'Oncologia (ICO) and the Germans Trias i Pujol Research Institute (IGTP) have found a new therapeutic strategy for patients with a specific subtype of metastatic prostate cancer resistant to standard chemotherapy treatment with docetaxel.

5 Feb 2024

SLAS 2024 press release from Veranex

Veranex provider of the first purpose-built, global service platform for the medtech industry, today announced that it has acquired T3 Labs, a highly reputable preclinical laboratory located in Atlanta, Georgia. This acquisition solidifies Veranex’s commitment to expanding its preclinical footprint in North

5 Feb 2024

Closing the Cancer Care Gap with the Power of Precision Oncology

According to American Cancer Society, Cancer causes about 1 in every 6 deaths globally, more than AIDS, tuberculosis, and malaria combined.

From MGI 5 Feb 2024

Clinical trials becoming more inclusive across race and ethnicity, new data shows

Clinical trials and medical research have been historically lacking in diversity among all groups.

5 Feb 2024

Does Sudarshan Kriya Yoga (SKY) practice reduce stress and increase well-being in practicing physicians?

The efficacy of SKY in reducing psychological distress and enhancing wellness among physicians at risk of burnout.

5 Feb 2024

Lentils lower cholesterol and sugar response, study finds

Twelve weeks of daily lentil consumption significantly improves fasting cholesterol, postprandial glucose, and inflammation in overweight adults, offering a dietary strategy to enhance metabolic health without gastrointestinal distress.

4 Feb 2024

New vaccine may be potential off-the-shelf treatment for pancreatic, colorectal cancer

A new vaccine shows encouraging early results as a potential off-the-shelf treatment for certain patients with pancreatic or colorectal cancer, according to a study co-led by researchers at Memorial Sloan Kettering Cancer Center (MSK).

2 Feb 2024

$Large trial finds iodine-based antiseptic to be more effective for closed fracture surgery$

Large trial finds iodine-based antiseptic to be more effective for closed fracture surgery

A large multicenter clinical trial co-led by University of Maryland School of Medicine researchers large multicenter clinical trial co-led by University of Maryland School of Medicine researchers found that an antiseptic containing iodine resulted in about one-quarter fewer post-surgical infections in patients with limb fractures compared to another frequently used skin antiseptic.

2 Feb 2024

Viscoelasticity emerges as key marker for liver cancer in diabetes

For centuries, doctors have used their hands as essential diagnostic tools -; exploring joints and palpating abdomens to assess a patient's health.

2 Feb 2024

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Clinical Trial News and Research

Reducing unnecessary testing or treatments in older patients

AMG 133 (maridebart cafraglutide) weight loss drug shows promise in early trial

Snacking on pistachios may combat metabolic syndrome risk without weight gain

Experimental mRNA vaccine against CMV elicits promising immune responses

New link between stress, immune system, and depression discovered

AI helps predict antidepressant response in a week

Eleven stroke researchers to be recognized during the 2024 International Stroke Conference

New cell therapy shows promise for critically ill COVID-19 patients with ARDS

Doppler ultrasound detects placental issues in small babies, study finds

New weight loss drug may be an effective strategy for preventing or treating high blood pressure

First gene therapy trial aims to restore hearing in children

PI3K/AKT and MEK/ERK pathways targeted in new therapy for docetaxel-resistant prostate cancer

SLAS 2024 press release from Veranex

Closing the Cancer Care Gap with the Power of Precision Oncology

Clinical trials becoming more inclusive across race and ethnicity, new data shows

Does Sudarshan Kriya Yoga (SKY) practice reduce stress and increase well-being in practicing physicians?

Lentils lower cholesterol and sugar response, study finds

New vaccine may be potential off-the-shelf treatment for pancreatic, colorectal cancer

Large trial finds iodine-based antiseptic to be more effective for closed fracture surgery

Viscoelasticity emerges as key marker for liver cancer in diabetes

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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