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Combination drug treatment could be effective against malignant peripheral nerve sheath tumors

A combination of two cancer drugs could be effective against malignant peripheral nerve sheath tumors (MPNSTs) -; soft tissue tumors that are stubbornly resistant to chemotherapy and radiation -; according to a laboratory study led by researchers at the Johns Hopkins Kimmel Cancer Center.

31 Jan 2024

Enterprise Therapeutics closes £26 million ($33.1 million) Series B follow-on financing

Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of patients suffering from respiratory disease, today announced that it has closed a £26 million ($33.1 million USD) Series B follow-on financing round, led by Panakes Partners.

From Enterprise Therapeutics Ltd 31 Jan 2024

Scientists regenerate fully functional urinary bladder tissue using a non-human primate model

Scientists from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago and Northwestern University succeeded in regenerating fully functional urinary bladder tissue in a long-term study utilizing a non-human primate model.

30 Jan 2024

Gastric bypass and sleeve tie in short-term complications

The two most common obesity surgeries – gastric bypass and gastric sleeve – have few short-term complications and are equivalent in that sense.

30 Jan 2024

Gene therapy could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy

A new study in mice shows that replacement of a dysfunctional gene could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy (ARVC), a rare inherited disorder in which the muscular walls of the heart progressively weaken and put patients at risk of dangerous irregular heartbeats.

30 Jan 2024

Weight loss in people with type 2 diabetes can change cancer-related proteins

A weight loss intervention in people with type 2 diabetes was found to alter levels of cancer-related proteins, according to the findings of a new University of Bristol-led study.

30 Jan 2024

DiAL-Health study aims to determine how time-restricted eating can slow aging and improve 'healthspan'

January is a time when many people are looking for new diet routines, and intermittent fasting is trending, as are traditional calorie cutting programs.

30 Jan 2024

How do mass spectrometry and omics impact neurosciences?

In this new episode of omg OMx, Kate Stumpo speaks to Sapient's Tanya Nguyen about the role of omics and mass spectrometry in neurosciences.

From Bruker Life Sciences Mass Spectrometry 30 Jan 2024

Salmon's secret sauce: Nutrimetabolomics uncovers heart-healthy compounds in Mediterranean staple

Researchers use nutrimetabolomics to reveal that Salmon, a key component of the Mediterranean diet, contains unique compounds beneficial for cardiometabolic health.

29 Jan 2024

Hydroxyurea treatment can greatly benefit children with sickle cell anemia, study reveals

Clinical research led by Indiana University School of Medicine investigators and their collaborators in Uganda has revealed that hydroxyurea significantly reduces infections in children with sickle cell anemia.

29 Jan 2024

Subcutaneous nivolumab revolutionizes renal cell carcinoma care with faster, easier treatment

Subcutaneous injection of the immunotherapy nivolumab (brand name Opdivo) is noninferior to intravenous delivery and dramatically reduces treatment time in patients with renal cell carcinoma, as seen in the results of a large phase 3 clinical trial reported today at the 2024 American Society of Clinical Oncology (ASCO) Genitourinary Cancers Symposium in San Francisco, California.

29 Jan 2024

Trial: Physiotherapy after dislocated shoulder is no better than a single session of advice

Routinely referring patients to a tailored programme of physiotherapy after a dislocated shoulder is no better than a single session of advice, supporting materials and the option to self-refer to physiotherapy, finds a clinical trial published by The BMJ today.

27 Jan 2024

A certain type of chemotherapy found to improve the immune system's ability to fight off bladder cancer

Tisch Cancer Institute researchers discovered that a certain type of chemotherapy improves the immune system's ability to fight off bladder cancer, particularly when combined with immunotherapy, according to a study published in Cell Reports Medicine in January.

27 Jan 2024

Immunotherapy breakthrough: Pembrolizumab extends time to recurrence in aggressive bladder cancer

Patients with muscle-invasive urothelial cancer and a high risk of recurrence after surgery may have a new treatment option.

27 Jan 2024

Clinical study supports the long-lasting impacts of typhoid conjugate vaccine

A single dose of the typhoid conjugate vaccine, Typbar TCV, provides lasting efficacy in preventing typhoid fever in children ages 9 months to 12 years old, according to a new study conducted by researchers at University of Maryland School of Medicine's (UMSOM) Center for Vaccine Development and Global Health (CVD) and led by in-country partners at the Malawi-Liverpool Wellcome Trust (MLW) Clinical Research Programme.

25 Jan 2024

UCL's neuro research to be supported by e-money venture Science Card

A UCL research team developing an artificial fiber technology to accelerate neurodegenerative disease clinical trials will be one of the first studies supported by e-money venture Science Card.

25 Jan 2024

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Currently used Food and Drug Administration-approved transplant drugs -; with the addition of an also already FDA-approved complement inhibitor -; are the optimal immunosuppression regimen for pig-to-human kidney transplants, according to a landmark discovery by University of Alabama at Birmingham investigators.

25 Jan 2024

Unbiased assessment of vamorolone for treating Duchenne muscular dystrophy

The drug vamorolone (Agamree) has been hailed as a promising new drug to treat Duchenne muscular dystrophy (DMD).

25 Jan 2024

Study shows effectiveness of gene therapy in treating congenital deafness

A new study co-led by investigators from Mass Eye and Ear, a member of Mass General Brigham, demonstrated the effectiveness of a gene therapy towards restoring hearing function for children suffering from hereditary deafness.

24 Jan 2024

Researchers secure $1.5 million grant to eliminate barriers from cervical cancer prevention

A research team from LSU LCMC Health Cancer Center has been awarded a $1.5 million grant to eliminate barriers from cervical cancer prevention. The five-year program combines a $1.2 million award from the American Cancer Society and $75,000 a year for five years investment from LSU Health New Orleans.

24 Jan 2024

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Clinical Trial News and Research

Combination drug treatment could be effective against malignant peripheral nerve sheath tumors

Enterprise Therapeutics closes £26 million ($33.1 million) Series B follow-on financing

Scientists regenerate fully functional urinary bladder tissue using a non-human primate model

Gastric bypass and sleeve tie in short-term complications

Gene therapy could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy

Weight loss in people with type 2 diabetes can change cancer-related proteins

DiAL-Health study aims to determine how time-restricted eating can slow aging and improve 'healthspan'

How do mass spectrometry and omics impact neurosciences?

Salmon's secret sauce: Nutrimetabolomics uncovers heart-healthy compounds in Mediterranean staple

Hydroxyurea treatment can greatly benefit children with sickle cell anemia, study reveals

Subcutaneous nivolumab revolutionizes renal cell carcinoma care with faster, easier treatment

Trial: Physiotherapy after dislocated shoulder is no better than a single session of advice

A certain type of chemotherapy found to improve the immune system's ability to fight off bladder cancer

Immunotherapy breakthrough: Pembrolizumab extends time to recurrence in aggressive bladder cancer

Clinical study supports the long-lasting impacts of typhoid conjugate vaccine

UCL's neuro research to be supported by e-money venture Science Card

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Unbiased assessment of vamorolone for treating Duchenne muscular dystrophy

Study shows effectiveness of gene therapy in treating congenital deafness

Researchers secure $1.5 million grant to eliminate barriers from cervical cancer prevention

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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