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Researchers create artificial cornea using pig and human stem cells

Researchers extracted pig corneal cells and replaced them with human stem cells. Thus, the University of Granada takes the lead in the making of bioartificial organs, a field so far led by the Hospital Gregorio Marañón in Madrid.

15 Apr 2011

Quest PharmaTech, Hemispherx Biopharma enter clinical development arrangement

Quest PharmaTech Inc., a pharmaceutical company developing and commercializing products for the treatment of cancer, today announced a clinical development arrangement with U.S. based Hemispherx Biopharma Inc. to evaluate the clinical utility of combining Quest's antibody immunotherapy technology with Hemispherx's immune activator in a thirty patient clinical trial.

15 Apr 2011

Researchers develop non-steroid based strategy for patients with COPD

Researchers at the Johns Hopkins Bloomberg School of Public Health have developed a non-steroid based strategy for improving the lung's innate immune defense and decreasing inflammation that can be a problem for patients with chronic obstructive pulmonary disease.

15 Apr 2011

Diet and exercise most effective when done together for losing weight and body fat

Everyone knows that eating a low-fat, low-calorie diet and getting regular exercise helps shed pounds, but a new study led by researchers at Fred Hutchinson Cancer Research Center has found that when it comes to losing weight and body fat, diet and exercise are most effective when done together as compared to either strategy alone.

15 Apr 2011

Perampanel drug can effectively treat seizures in patients with epilepsy

A new drug called perampanel appears to significantly reduce seizures in people with hard-to-control epilepsy, according to results of the first clinical trial to test the higher 12 mg dose of the drug.

15 Apr 2011

Study finds association between C-reactive protein and memory decline

High levels of a protein associated with chronic, low-grade inflammation in the brain correlate with aspects of memory decline in otherwise cognitively normal older adults, according to a study led by scientists at the University of California, San Francisco.

15 Apr 2011

Sirolimus may help treat lymphangioleiomyomatosis in women

An Oregon Health & Science University researcher has co-authored an international study that revealed a drug approved to prevent rejection in organ transplant patients helped treat a rare lung disease in women.

12 Apr 2011

Positive results from ULCA's Phase 1 dendritic cell vaccine trial in glioblastoma

A novel brain tumor vaccine clinical trial study demonstrates a longer survival time in patients with glioblastoma, according to findings being presented at the 79th Annual Scientific Meeting of the American Association of Neurological Surgeons in Denver.

12 Apr 2011

Novel drug holds potential against resistant chronic myeloid leukemia

A study from Tufts Medical Center researchers published today finds that a novel drug shows promise for treating leukemia patients who have few other options because their disease has developed resistance to standard treatment.

12 Apr 2011

Top-line results from DURECT's ELADUR Phase II trial in chronic low back pain

DURECT Corporation announced today top-line results from a Phase II clinical trial in chronic low back pain for ELADUR, DURECT's proprietary investigational transdermal bupivacaine pain patch.

12 Apr 2011

Epilepsy medication USL255 associated with less fluctuation in plasma levels compared to topiramate IR

Upsher-Smith Laboratories today announced the presentation of data indicating that once daily administration of USL255, a proprietary extended-release (ER) formulation of the epilepsy medication topiramate, was associated with less fluctuation in topiramate plasma levels compared to immediate-release (IR) topiramate administered twice daily in healthy volunteers.

12 Apr 2011

NCI awards MabVax with Phase II SBIR grant to develop vaccine against recurrent sarcoma

MabVax Therapeutics, Inc., a privately held clinical stage biotechnology company focused on the development of vaccine and antibody based therapies to address the unmet medical need of preventing recurrent cancer, announces that it has received the Phase 2 portion of the Small Business Innovation Research Grant from the National Cancer Institute under the agency's Streamlined Non-competing Award Procedures.

11 Apr 2011

Positive interim results from PROLOR's hGH-CTP Phase II trial in growth hormone deficiency

PROLOR Biotech, Inc. today reported positive interim efficacy results from a Phase II clinical trial of its long-acting CTP-modified version of human growth hormone in growth hormone deficient adults.

11 Apr 2011

Positive top-line results from Biogen BG-12 Phase 3 trial in RRMS

Biogen Idec announced today positive top-line results from DEFINE, the first of two pivotal Phase 3 clinical trials designed to evaluate the investigational oral compound BG-12 as a monotherapy in people with relapsing-remitting multiple sclerosis.

11 Apr 2011

Study shows how specific nutritional combination may help maintain healthy breast tissue

Researchers from Canada and the United States today told attendees of the Experimental Biology 2011 Scientific Meeting that they have uncovered a possible means of enabling women to favorably influence whether the estrogens in their bodies take a "beneficial path" or a "disease-potential" path.

11 Apr 2011

Enigma initiates ML system trial in patients with influenza

Enigma Diagnostics announced today that it has commenced clinical trials for its intended point of care Enigma ML Influenza A/B detection assay. Enigma will submit its application to the U.S. Food and Drug Administration for approval of the assay in 2012.

11 Apr 2011

Research on rare cancers

A cancer diagnosis can be a life-changing event. Many questions arise, with one of the first being, "Where should I be treated?" Patients diagnosed with rare cancers may have difficulty finding a physician knowledgeable in treating their type of cancer.

11 Apr 2011

Clinical Trial News and Research

Researchers create artificial cornea using pig and human stem cells

Quest PharmaTech, Hemispherx Biopharma enter clinical development arrangement

Researchers develop non-steroid based strategy for patients with COPD

Diet and exercise most effective when done together for losing weight and body fat

Perampanel drug can effectively treat seizures in patients with epilepsy

Study finds association between C-reactive protein and memory decline

Sirolimus may help treat lymphangioleiomyomatosis in women

Positive results from ULCA's Phase 1 dendritic cell vaccine trial in glioblastoma

Novel drug holds potential against resistant chronic myeloid leukemia

Top-line results from DURECT's ELADUR Phase II trial in chronic low back pain

Epilepsy medication USL255 associated with less fluctuation in plasma levels compared to topiramate IR

NCI awards MabVax with Phase II SBIR grant to develop vaccine against recurrent sarcoma

Positive interim results from PROLOR's hGH-CTP Phase II trial in growth hormone deficiency

Positive top-line results from Biogen BG-12 Phase 3 trial in RRMS

Study shows how specific nutritional combination may help maintain healthy breast tissue

Enigma initiates ML system trial in patients with influenza

Research on rare cancers

Synexus' Chief Medical Officer to discuss vaccine trial challenges at Washington event

Annals of Neurology publishes Diamyd Medical´s NP2 Enkephalin Phase I results in cancer pain

New point-of-care trial can reduce cost and length of studies

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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