Clinical Trial News and Research

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Bupropion plus counseling appears to help adolescents quit cigarette smoking in the short term

Almost one-fourth of U.S. high school students currently smoke cigarettes, according to background information in the article. Many teen smokers want to quit, but studies estimate that only about 4 percent of those who try are successful each year.

6 Nov 2007

More effective method of treating high blood pressure

Scientists at Robarts Research Institute have developed a simplified and more effective method of treating high blood pressure.

6 Nov 2007

Antioxidants inositol and inositol hexaphosphate could provide all-purpose radiation protection

Two common dietary molecules found in legumes and bran could protect DNA from the harmful effects of radiation, researchers from the University of Maryland report.

6 Nov 2007

Cancer victim comes up with a possible alternative to chemo

A cancer victim has invented a machine that could well replace traditional chemotherapy for the treatment of the disease.

5 Nov 2007

Antibody might help starve cancerous tumors

An antibody might offer a safe and effective complement to anti-cancer therapies designed to starve malignant tumors by pruning the blood vessels that feed them, researchers report in the November 2 issue of the journal Cell, a publication of Cell Press.

2 Nov 2007

Non-invasive radio waves heat up nanotubes to destroy cancer

Cancer cells treated with carbon nanotubes can be destroyed by non-invasive radio waves that heat up the nanotubes while sparing untreated tissue, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center and Rice University has shown in preclinical experiments.

2 Nov 2007

Increased glucose level is a strong risk factor for colorectal cancer

Diabetes is a very common illness that affects more than 20 million people in the U.S. and it is estimated an additional 54 million Americans have pre-diabetes, a condition that occurs when a person's blood glucose levels are higher than normal but not high enough for a diagnosis of type 2 diabetes.

2 Nov 2007

Panzem (2-methoxyestradiol ) drug a possible candidate for breast cancer treatment

A Mayo Clinic study of a drug that has shown promise in treating sarcoma, lung and brain cancers, demonstrates that the drug may also be effective in treating breast cancer, in particular the spread of breast cancer.

2 Nov 2007

Whole parasite malaria vaccine to be manufactured for clinical trials

Sanaria Inc. and the PATH Malaria Vaccine Initiative has officially opened a one-of-a-kind clinical manufacturing facility to produce a vaccine that uses a weakened form of the malaria parasite to fight a disease that annually kills more than one million people, most of them African children.

29 Oct 2007

Surgery, radiation gives early survival advantage in bile duct cancer

Oregon Health & Science University researchers are reporting the discovery of an early survival advantage when a combination of surgery and radiation therapy is used for patients with a rare but deadly bile duct cancer.

28 Oct 2007

Mindfulness-based stress reduction study

A researcher at the University at Buffalo's Research Institute on Addictions (RIA) is initiating a study of "mindfulness-based stress reduction," a technique often used in behavioral medicine for stress reduction but not before as an adjunct in the treatment of alcohol use disorders.

28 Oct 2007

Education program leads to lasting improvement of cancer knowledge in African Americans

Disparities in access to health care and education hinder minorities and socioeconomically disadvantaged populations from receiving needed cancer services and often lead to delayed cancer diagnoses.

28 Oct 2007

Positive results for novel anti-cancer drug ECO-4601

Researchers report positive results from a Phase I/II clinical trial of a novel anti-cancer drug which offers two modes of action.

24 Oct 2007

Oncolytics Biotech receives approval for UK clinical trial of of REOLYSIN

Oncolytics Biotech Inc. has announced that it has received a letter of approval from the U.K. Medicines and Healthcare products Regulatory Agency (MHRA) for its Clinical Trial Application (CTA) to begin a clinical trial using intravenous administration of REOLYSIN in combination with cyclophosphamide, a chemotherapeutic agent as well as immune modulator, in patients with advanced cancers.

24 Oct 2007

Genetics of alcoholism

While both environmental and genetic factors contribute to the risk of developing alcohol dependence, it is believed to be a largely heritable – 52 to 64 percent – disease.

24 Oct 2007

Potent inhibitor of Kinesin CENP-E demonstrates tumor cell inhibition

A first-in-class, targeted investigational therapy specifically designed to inhibit a single protein that functions only during cell division shows potent activity in a broad range of cancer cell lines, say researchers from GlaxoSmithKline.

24 Oct 2007

Combo therapy flavopiridol and cisplatin shows promise for recurrent ovarian cancer resistant to platinum therapy

Mayo Clinic has reported promising interim results from a Phase II trial of a new combination therapy for patients with recurrent ovarian cancer that is resistant to platinum therapy.

24 Oct 2007

SPIRIT III trial shows fewer major adverse cardiac events

Late breaking results from the SPIRIT III trial, presented at TCT 2007, the annual scientific symposium of the Cardiovascular Research Foundation, show that after 12 months, there were significantly fewer major adverse cardiac events (MACE) such as heart attacks, deaths from cardiac causes or repeat procedures (angioplasty or surgery) to clear the original vessel blockage after using a Xience V everolimus-eluting coronary stent than a Taxus paclitaxel-eluting stent.

24 Oct 2007

Experimental cancer pharmaceuticals under trial

A potent and selective inhibitor of the mitotic kinesin CENP-E (GSK923295A) demonstrates a novel mechanism of inhibiting tumor cell proliferation and shows activity against a broad panel of human tumor cell lines in vitro: Abstract A 111.

24 Oct 2007