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Inhibiting MET signaling in glioblastoma has major therapeutic value

A recent discovery by Van Andel Research Institute (VARI) scientists enables the prediction of patient sensitivity to proposed drug therapies for glioblastoma - the most common and most aggressive malignant brain tumor in humans.

7 Feb 2012

Pyromaker can more accurately identify complex genetic mutations

DNA sequencing to detect genetic mutations can aid in the diagnosis and selection of treatment for cancer. Current methods of testing DNA samples, Sanger sequencing and pyrosequencing, occasionally produce complex results that can be difficult or impossible to interpret. Scientists at the Johns Hopkins University School of Medicine have developed a free software program, Pyromaker, that can more accurately identify such complex genetic mutations.

6 Feb 2012

Specific gene mutation triggers development of NAFLD

A team of scientists from the University of Utah and the University of California at San Francisco has discovered that the mutation of a gene encoding a ketone body transporter triggers accumulation of fat and other lipids in the livers of zebrafish.

1 Feb 2012

New gene therapy shows promise against X-linked retinitis pigmentosa

A new gene therapy method developed by University of Florida researchers has the potential to treat a common form of blindness that strikes both youngsters and adults.

24 Jan 2012

Texas abortion issue back in court today

A Federal judge in Austin holds another hearing on Texas law requiring women seeking an abortion to have a sonogram. Also, NPR looks at the growing number of restrictions across the country.

21 Jan 2012

UCSF, Sanofi enter $3.1 million collaboration to identify diabetes drug targets

The University of California, San Francisco has signed an alliance with international pharmaceutical company Sanofi to share expertise in diabetes research and identify drug targets that could lead to new therapies for both type 1 and type 2 diabetes.

11 Jan 2012

Scientists regenerate functional muscle tissue in mice

A team of scientists from Worcester Polytechnic Institute (WPI) and CellThera, a private company located in WPI's Life Sciences and Bioengineering Center, have regenerated functional muscle tissue in mice, opening the door for a new clinical therapy to treat people who suffer major muscle trauma.

30 Nov 2011

State roundup: Md.'s medical home; N.Y. malpractice action; Texas nursing homes

Instead of a doctor seeing patients mostly when they're sick -; and the physician is getting paid for that visit or service -; this program gives financial rewards to practices that use a team of doctors, nurses and other staff to treat the whole person on a continuing basis, not just for one illness. ... The state initiative is among dozens of public and private experiments across the country that are trying to fundamentally change the way doctors practice medicine.

15 Nov 2011

Positive results from ChemoCentryx CCX354 Phase II study on RA

ChemoCentryx, Inc., today announced that it reported positive Phase II results for CCX354 at the Annual Meeting of the American College of Rheumatology.

9 Nov 2011

Abortion and 'personhood' on GOP campaign agenda

State-level initiatives to restrict access to abortions help make social issues a major focus of the Republican presidential nomination contest.

7 Nov 2011

Longer looks: A doctor's dilemma on C-sections; apology for a death sparked a hospital's change

I was the obstetrician on hospital duty that Sunday morning, so I introduced myself and learned that the patient, pregnant with her first child, wished to have as few interventions as possible. Respecting her desire, we decided to reevaluate her in a few hours to see how her labor had progressed. But would she get her wish? ... the odds were greater than 1 in 4 that this woman would end up not with the natural delivery she wanted, but with a surgical delivery in one of the two operating rooms down the hall.

4 Nov 2011

Viewpoints: Super committee clock is ticking; replacing CLASS; 'personhood' amendment in Miss.

There are only three weeks left for the Congressional supercommittee to come up with a plan to reduce the federal deficit by at least $1.2 trillion, and there is no sign that the panel is anywhere close to reaching an agreement. Only one side, in fact, seems to be trying -; the Democrats -; and it is being far too accommodating, given the fierce obstructionism of the other side, the Republicans.

2 Nov 2011

Viewpoints: Judd Gregg on revamping entitlements and taxes; John Breaux on slashing Medicare fraud; Medicaid limits on hospital stays

Consider this. As of this year, every other household in America will have at least one person in it who is receiving an entitlement benefit, according to the Census Bureau. As of this year, fewer than half of the Americans who have earned income will pay income taxes on that income.

1 Nov 2011

Thyroid researcher to receive ATA's John B. Stanbury Pathophysiology Medal

Each year, the American Thyroid Association (ATA) recognizes the outstanding research contributions of one of its members to a greater understanding of thyroid physiology or the pathophysiology of thyroid disease, with its presentation of the John B. Stanbury Pathophysiology Medal at its Annual Meeting.

29 Oct 2011

Researchers identify stem cells responsible for lung regeneration

Guided by insights into how mice recover after H1N1 flu, researchers at Harvard Medical School and Brigham and Women's Hospital, together with researchers at A*STAR of Singapore, have cloned three distinct stem cells from the human airways and demonstrated that one of these cells can form into the lung's alveoli air sac tissue.

28 Oct 2011

Longer looks: Miss. ballot-initiative on abortion; personal fortune may have helped Herman Cain battle cancer; for doctors, breaking up is hard to do

One evening in late September John Perkins, a veteran of the civil-rights movement, attended a rally at a Baptist church in Jackson in support of what he called "a total justice issue," … It was concerned with Amendment 26, a measure on Mississippi's ballot this November that defines a person as being "every human being from the moment of fertilisation, cloning or the functional equivalent thereof". The reason for the measure is straightforward; its consequences less so. The Supreme Court, in its landmark Roe v Wade ruling in 1973, held that the right of a woman to terminate her pregnancy in the first trimester was guaranteed by her constitutional right to privacy.

14 Oct 2011

Thriving stem cells created by cloning technique

In a breakthrough that has been debated and awaited for long, scientists have finally derived colonies of embryonic stem cells from human embryos created using cloning technology.

6 Oct 2011

Jeffrey C. Hall, Michael W. Young and Michael Rosbash to receive 2011 Louisa Gross Horwitz Prize

Columbia University will award the 2011 Louisa Gross Horwitz Prize to Jeffrey C. Hall, Michael Rosbash, and Michael W. Young for their work on the molecular basis of circadian rhythms, the first demonstration of a molecular mechanism for behavior.

1 Oct 2011

House GOP lawmakers launch new investigation into Planned Parenthood

House Energy and Commerce Oversight and Investigations subcommittee Chairman Cliff Stearns, R-Fla., sent Planned Parenthood a six-page letter earlier this month requesting financial information and details on how the women's health organization keeps federal funds separate from abortion services.

29 Sep 2011

Genetically modified ‘glow cat’ for HIV/AIDS research

U.S. researcher Eric Poeschla has produced three glowing genetically modified cats by using a virus to carry a gene, called green fluorescent protein (GFP), into the eggs from which the animals eventually grew. This method of genetic modification is simpler and more efficient than traditional cloning techniques, and results in fewer animals being needed in the process.

12 Sep 2011