Colorectal News and Research

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Primary care doctors miss opportunities to recommend colon cancer screening

While it is known that patients with few primary care doctor's office visits are less likely to receive colorectal cancer screening, new research indicates that even patients who see their physicians regularly also do not receive screening.

3 Feb 2009

New inhibitors could be new class of cancer drugs

A team of Vanderbilt University Medical Center investigators has developed a group of chemical compounds that could represent a new class of drugs for treating cancer.

3 Feb 2009

New potential targets for colitis-associated cancer

Recent research from the laboratory of Michael Karin, PhD, at the University of California, San Diego School of Medicine - the first researcher to demonstrate a molecular link between inflammation and cancer - has identified two potential targets for the prevention and treatment of colitis-associated cancer (CAC), the most serious complication of inflammatory bowel disease.

2 Feb 2009

New CDC study assesses impact of genetic testing on health outcomes

Some genomic tests developed to personalize medical decisions about cancer care are beneficial, while for others the evidence is uncertain and reliance on the test might even lead to poorer medical management of cancer in some cases, according new recommendation statements from an expert panel.

2 Feb 2009

Pre-emptive treatment helped curtail skin toxicity with Panitumumab

With a pre-emptive, prophylactic skin regimen, patients who receive panitumumab for treatment of metastatic colorectal cancer may be able to avoid some of the skin-associated toxicities, according to data presented at the 2009 American Society of Clinical Oncology Gastrointestinal Cancers Symposium in San Francisco.

19 Jan 2009

Transarterial chemoembolization as liver cancer treatment

Using tiny chemotherapy-soaked beads to choke off and kill cancerous liver tumors is becoming more successful, according to research being presented at the 21st annual International Symposium on Endovascular Therapy (ISET).

19 Jan 2009

Colonoscopy quality critical factor to thorough exam and best colon cancer detection

Publication of a meta-analysis by Wilkins et al. on colonoscopy screening for colorectal cancer performed by primary care physicians raises several important issues regarding the quality of the exam, the safety of patients and the effectiveness of detecting colorectal cancer and pre-cancerous changes in the colon.

13 Jan 2009

Estrogen plus progestin therapy may decrease risk of colorectal cancer

The combination of estrogen plus progestin, which women stopped taking in droves following the news that it may increase their risk of breast cancer, may decrease their risk of colorectal cancer, according to a report published in the January issue of Cancer Epidemiology, Biomarkers and Prevention , a journal of the American Association for Cancer Research.

8 Jan 2009

Genomics in China

Ten years ago, the Chinese National Human Genome Center at Shanghai (South Center, hereafter) was established in the Zhangjiang HiTech Park of Pudong District in Shanghai.

7 Jan 2009

New online tool for calculating colorectal cancer risk

A new online tool for calculating colorectal cancer risk in men and women age 50 or older was launched today, based on a new risk-assessment model developed by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health.

1 Jan 2009

Bowel cancer screening set to save thousands of lives

Bowel cancer screening is predicted to save over two and a half thousand lives every year in the UK by 2025, according to new research published in the Journal of Medical Screening.

29 Dec 2008

Drinkers with the ADH1C gene at greater risk of colorectal cancer

Chronic drinking is a risk factor for colorectal cancer, possibly through the effects of acetaldehyde, which is created by the alcohol dehydrogenase (ADH) enzyme.

21 Dec 2008

Merck KGaA acquires manufacturing rights for Stimuvax from Oncothyreon

Oncothyreon Inc. announced today that Merck KGaA of Darmstadt, Germany has licensed the right to manufacture Stimuvax and, through its affiliate EMD Serono Canada Inc., purchased current inventory and certain assets utilized for the manufacture of Stimuvax from Oncothyreon for consideration which includes net payments to Oncothyreon totaling approximately U.S. $13 million.

18 Dec 2008

Smoking significantly linked to increased risk for colorectal cancer

An analysis of previous studies indicates that smoking is significantly associated with an increased risk for colorectal cancer and death, according to an article in the December 17 issue of JAMA, the Journal of the American Medical Association.

16 Dec 2008

Non-invasive stool-based DNA screening for colon cancer recognized more broadly as standard of care

EXACT Sciences Corporation today commented on the addition of non-invasive stool-based DNA (sDNA) testing to the state colorectal cancer screening mandates of New Jersey and Maryland, as well as the decision by CIGNA, one of the nation's largest insurers, to include sDNA screening among its covered benefits nationally.

16 Dec 2008

Study highlights importance of seeking a qualified gastrointestinal endoscopist to perform a thorough colonoscopy

A study released today in the Annals of Internal Medicine found that colonoscopy is associated with lower death rates from colorectal cancer, however, the procedure missed lesions more often on the right side of the colon versus the left side.

16 Dec 2008

USA's largest ever prostate cancer screening program shows high compliance and consistent results

Just under five per cent of the men who took part in the prostate cancer element of the USA's largest ever cancer screening trial were diagnosed with the disease and the majority of those were picked up by screening programmes, according to research published in the December issue of the urology journal BJU International .

15 Dec 2008

Discovery of promising new target in the battle against colorectal cancer

University of Texas Medical Branch at Galveston researchers have identified a promising new target in the battle against colorectal cancer - a biochemical pathway critical to the spread of tumors to new locations in the body.

15 Dec 2008

Narrow-band imaging comparable to white light colonoscopy in differentiating colorectal polyps

Researchers from Yale University School of Medicine compared narrow-band imaging (NBI) without high magnification to standard white light colonoscopy in differentiating colorectal polyps during real-time colonoscopy and found that NBI was not more accurate than white light colonoscopy.

15 Dec 2008