Colorectal News and Research

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Double binding sites on tumor target may provide future combination therapy

Researchers from the University of Pennsylvania School of Medicine and colleagues at Merck Serono Research in Germany have found that two drugs bind to receptor sites on some tumors in different places at the same time, suggesting the possibility of a new combination therapy for certain types of cancer.

9 Apr 2008

$2.9 million to reduce colorectal cancer screening disparities in Vietnamese Americans

The Vietnamese REACH for Health Initiative coalition, under the leadership of the Northern California Cancer Center was recently awarded a $2.9 million grant from the National Institute of Health to evaluate the effectiveness of a colorectal cancer lay health worker and media intervention in increasing colorectal cancer screening among Vietnamese Americans aged 50-74 in Santa Clara County, California.

7 Apr 2008

Patient interventions with low-income and minorities increases colonoscopy rates

Patient interventions are necessary to achieve higher rates of colorectal cancer screening in low-income and minority patients, according to two studies in the current issue of Clinical Gastroenterology and Hepatology , the official journal of the American Gastroenterological Association (AGA) Institute.

2 Apr 2008

Chemotherapy-induced anemia increases risk of local breast cancer recurrence

Patients with breast cancer who developed anemia during chemotherapy had nearly three times the risk of local recurrence as those who did not, according to a study published in the April 1 issue of Clinical Cancer Research¸ a journal of the American Association for Cancer Research.

2 Apr 2008

New type of imaging system illuminates tumors to nearly one-trillionth of a meter

Doctors' quest to see what is happening inside a living body has been hampered by the limits on detecting tiny components of internal structures and events.

1 Apr 2008

Racial differences in response to bowel cancer genetic risk factor

Scientists have for the first time discovered that people with the same cancer susceptibility genes respond differently depending on their race.

1 Apr 2008

Replacing absent microRNAs could make tumors less invasive, more treatable

One group of small, non-coding RNA molecules could serve as a marker to improve cancer staging and may also be able to convert some advanced tumors to more treatable stages, report a University of Chicago-based research team in the April 1, 2008, issue of the journal Genes & Development.

1 Apr 2008

Saving cancer patients' skin

Becky Sasaki has the quick laugh and easy smile of a woman who continues to thrive despite her four-year wrestling match with lung cancer.

31 Mar 2008

Pectin-rich apple products shown to have anticarcinogenic effects on colon

The apples and apple juice you consume may have positive effects in one of the most unlikely places in the body – in the colon.

28 Mar 2008

Softening of the skull bones in normal-looking babies might reflect vitamin D deficiency during pregnancy

Softening of the skull bones in normal-looking babies might reflect vitamin D deficiency during pregnancy, according to a new study accepted for publication in the Journal of Clinical Endocrinology & Metabolism (JCEM).

26 Mar 2008

Spit in a cup to replace needle pricks

One day soon patients may spit in a cup, instead of bracing for a needle prick, when being tested for cancer, heart disease or diabetes.

26 Mar 2008

Review of group-based cancer trials reveals flaws in studies' design and analysis

A new study reviewing 75 group-randomized cancer trials over a five-year stretch shows that fewer than half of those studies used appropriate statistical methods to analyze the results.

26 Mar 2008

A new form of inherited risk of cancer found

Like the subtext of a novel, the human genome sequence harbors more information than appears just in its "letters" of A, C, T and G. Since DNA is a data-packed molecule passed from generation to generation, comparing genome sequences among individuals also holds clues to ancestry.

26 Mar 2008

Obesity may keep some women from getting screened for cancers

A review of cancer screening studies shows that white women who are obese are less likely than healthy weight women to get the recommended screenings for breast and cervical cancer, according to researchers at the University of North Carolina at Chapel Hill's School of Public Health.

25 Mar 2008

Researchers make colorectal screening a little easier

Colon cancer screening is a tough sell. It's icky, uncomfortable and the thought of a colonoscopy, especially the prep, can be intimidating, to say the least.

25 Mar 2008

Blacks with family history less likely than whites to get colonoscopy

African Americans who have multiple first-degree relatives with colon cancer are less likely than whites with affected relatives to undergo recommended screening procedures, according to a report in the March 24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

25 Mar 2008

Review of supplement use among US cancer patients

Many of the 10 million cancer patients in the US are taking nutritional supplements, but an accurate assessment of the frequency is not well appreciated.

24 Mar 2008

Review of supplement use among US cancer patients

Many of the 10 million cancer patients in the US are taking nutritional supplements, but an accurate assessment of the frequency is not well appreciated.

20 Mar 2008

Increased hepcidin expression: A novel oncogenic signalling mechanism

Historically anaemia, which is associated with colorectal cancer, has been attributed to blood loss.

19 Mar 2008

Long-term follow-up after percutaneous pulmonary radiofrequency ablation

Radiofrequency ablation (RFA) - an interventional treatment that "cooks" and kills lung cancer tumors with heat - greatly improves survival time from primary or metastatic inoperable lung tumors, according to a study released at the Society of Interventional Radiology's 33rd Annual Scientific Meeting.

18 Mar 2008