Colorectal News and Research

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CT colonography best choice for regular screening for cancer

Colorectal cancer is the second leading cause of cancer deaths in most developed countries. Screening for colorectal malignancies and polyps (which frequently become cancerous) has been shown to lower the number of deaths from cancer. Most cancer societies and preventive task forces recommend regular screening for cancer of the colon.

10 Oct 2005

Colorectal cancer screening rates are too low

An intervention program designed to promote screening for colorectal cancer – and thereby decrease the number of cancers diagnosed - failed to increase screening rates in the managed care setting, a University of California - Los Angeles study has found.

10 Oct 2005

Important milestone towards more individually targeted and effective treatments for cancer patients

The research team has now identified crucial genes in a range of common cancers that have been reported to predict a patient's response to treatment. This follows the team's earlier success in studying a tumor suppressor gene associated with acute lymphoblastic leukaemia (ALL) in children.

9 Oct 2005

Gene variation may play fundamental role in the development and spread of cancer in the body

New research shows that a small gene variation that increases the risk of inherited cancer can also arise during the development of spontaneous, or non-inherited, tumors.

9 Oct 2005

Americans' risk of dying from cancer continues to decline

The nation's leading cancer organizations report that Americans' risk of dying from cancer continues to decline and that the rate of new cancers is holding steady. The "Annual Report to the Nation on the Status of Cancer, 1975-2002," published in the Oct. 5, 2005, issue of the Journal of the National Cancer Institute, shows observed cancer death rates from all cancers combined dropped 1.1 percent per year from 1993 to 2002.

4 Oct 2005

Common cancer susceptibility gene appears to be frequently acquired in metastatic lesions from colorectal cancer

A relatively common cancer susceptibility gene appears to be frequently acquired in metastatic lesions from colorectal cancer, and give cancer cells a growth advantage, according to a study in the October 5 issue of JAMA: The Journal of the American Medical Association.

4 Oct 2005

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

...a discovery that could pave the way for more effective cancer treatments.

27 Sep 2005

Mutations in receptor tyrosine kinases provide potential for highly-targeted cancer therapies

Scientists from J. Craig Venter Institute, Ludwig Institute for Cancer Research, and The Johns Hopkins University School of Medicine identified three novel mutations in two receptor tyrosine kinases in glioblastoma tumors using high throughput sequencing.

26 Sep 2005

Change in gene may be underlying molecular defect in some colorectal cancers

Inactivation of a DNA repair gene may be an early step in the development of sporadic colorectal tumors, and detection of the molecular basis for this inactivation may ultimately be useful in risk assessment for colorectal cancer, according to a new study in the current issue of the Journal of the National Cancer Institute.

22 Sep 2005

Dual association of beta-carotene with risk of tobacco-related cancers

A new study of French women has found that high beta-carotene intake--through a combination of diet or supplementation--is associated with a higher risk of tobacco-related cancers in smokers, but the risk of these cancers decreases with increasing beta-carotene intake in nonsmokers.

20 Sep 2005

Change in gene may be underlying molecular defect in some colorectal cancers

Inactivation of a DNA repair gene may be an early step in the development of sporadic colorectal tumors, and detection of the molecular basis for this inactivation may ultimately be useful in risk assessment for colorectal cancer, according to a new study in the September 21 issue of the Journal of the National Cancer Institute.

20 Sep 2005

Taking aspirin longterm could reduce colorectal cancer risk

According to new report from the Nurses' Health Study (NHS), regular, long-term aspirin use can significantly reduce the risk of colorectal cancer.

24 Aug 2005

Aspirin use can significantly reduce the risk of colorectal cancer

A new report from the Nurse's Health Study finds that regular, long-term aspirin use can significantly reduce the risk of colorectal cancer, as suggested by several earlier studies.

23 Aug 2005

Cancer Research Technology licenses novel cancer diagnostic markers

Cancer Research Technology Limited announced today that they have entered into a worldwide license agreement with TriPath Imaging, Inc.

22 Aug 2005

Mutations in the targets of designer drugs critically influence their effectiveness

Two designer cancer drugs differed dramatically in a laboratory test comparing their ability to shut down a mutant, overactive growth signal in lung cancer cells, reports a team headed by scientists at the Dana-Farber Cancer Institute.

18 Aug 2005

Men and women receive remarkably similar outpatient care at the Department of Veterans Affairs (VA),

The study looked at nine measures of quality care that are equally appropriate for women and men, including pneumonia and influenza vaccinations; colorectal cancer screenings; and eye examinations for diabetics, to determine what percentage of VA patients received appropriate care for their gender.

11 Aug 2005

FDA approval sought for Pfizer's new cancer drug

Drug company Pfizer has announced it has submitted a New Drug Application (NDA) for its cancer drug Sutent, to the U.S. Food and Drug Administration (FDA).

11 Aug 2005

Important breast cancer discovery

Scientists at the McGill University Health Centre (MUHC) have made an important discovery that will advance our understanding of how the female hormone estrogen causes growth of breast cancer cells. The research, in collaboration with scientists at the Institut de Recherches Cliniques de Montreal (IRCM) identifies 153 genes that respond to estrogen and one in particular that can be used to halt the growth of breast cancer cells.

10 Aug 2005

Switching treatment to the drug anastrozole after two years of tamoxifen is beneficial for women with early breast cancer

Switching treatment to the drug anastrozole after two years of tamoxifen can improve eventfree survival for postmenopausal women with early breast cancer, concludes a study in this week’s issue of The Lancet.

4 Aug 2005

Vimentin marker detects colon cancer in 46 percent of patients

Researchers at Case Western Reserve University School of Medicine and the Ireland Cancer Center of University Hospitals of Cleveland report identifying a new DNA gene marker, vimentin, that was shown in a recent study to be three times more effective in detecting colon cancer than the standard doctor's office test that detects blood in the stool.

2 Aug 2005

Colorectal News and Research

CT colonography best choice for regular screening for cancer

Colorectal cancer screening rates are too low

Important milestone towards more individually targeted and effective treatments for cancer patients

Gene variation may play fundamental role in the development and spread of cancer in the body

Americans' risk of dying from cancer continues to decline

Common cancer susceptibility gene appears to be frequently acquired in metastatic lesions from colorectal cancer

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

Mutations in receptor tyrosine kinases provide potential for highly-targeted cancer therapies

Change in gene may be underlying molecular defect in some colorectal cancers

Dual association of beta-carotene with risk of tobacco-related cancers

Change in gene may be underlying molecular defect in some colorectal cancers

Taking aspirin longterm could reduce colorectal cancer risk

Aspirin use can significantly reduce the risk of colorectal cancer

Cancer Research Technology licenses novel cancer diagnostic markers

Mutations in the targets of designer drugs critically influence their effectiveness

Men and women receive remarkably similar outpatient care at the Department of Veterans Affairs (VA),

FDA approval sought for Pfizer's new cancer drug

Important breast cancer discovery

Switching treatment to the drug anastrozole after two years of tamoxifen is beneficial for women with early breast cancer

Vimentin marker detects colon cancer in 46 percent of patients

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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