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Carnitine supplementation appears to prevent development of liver cancer

A study will be published on March 21, 2009 in World Journal of Gastroenterology addresses the question.

24 Mar 2009

Discovery of new molecular mechanism for the processing of endocannabinoids

Dale Deutsch, Ph.D., Professor of Biochemistry and Cell Biology at Stony Brook University and colleagues discovered a new molecular mechanism for the processing of endocannabinoids, brain compounds similar to THC, the active ingredient in marijuana, and essential in physiological processes such as pain, appetite, and memory.

24 Mar 2009

Licorice may offer a new approach to preventing colorectal cancer

A chemical component of licorice may offer a new approach to preventing colorectal cancer without the adverse side effects of other preventive therapies, Vanderbilt University Medical Center researchers report.

23 Mar 2009

Injected luminol glows blue revealing immune cells' misdeeds

Detectives on television shows often spray crime scenes with a compound called luminol to make blood glow.

22 Mar 2009

Metabolism and aging linked to circadian rhythm

All animals, including humans, have an internal 24-hour clock or circadian rhythm that creates a daily oscillation of body temperature, brain activity, hormone production and metabolism.

20 Mar 2009

Compound is key coordinator of clock and metabolism

Our circadian clock, or biological timing system, governs our daily cycles of feeding, activity and sleep.

20 Mar 2009

Alba Therapeutics announces next clinical trial of lead compound, Larazotide Acetate

Alba Therapeutics Corporation announced today it will initiate further clinical studies for patients diagnosed with celiac disease with their lead compound, larazotide acetate.

17 Mar 2009

Discovery of new mechanism for the processing of endocannabinoids

New research funded by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, has identified a new mechanism for the processing of endocannabinoids, natural brain compounds similar to THC, the active ingredient in marijuana.

17 Mar 2009

Budesonide nasal wash shows promise for chronic rhinosinusitis

A nasal wash containing the corticosteroid budesonide appears to reduce symptoms of chronic rhinosinusitis without suppressing the function of the adrenal glands, a known complication of this type of drug that would indicate absorption throughout the whole body, according to a report in the March issue of Archives of Otolaryngology-Head & Neck Surgery.

16 Mar 2009

Next generation antibiotic compounds that do not provoke bacterial resistance

Bacterial resistance to antibiotics is one of medicine's most vexing challenges.

15 Mar 2009

Schering-Plough's investigational oral thrombin receptor antagonist meets primary endpoint in a newly published study

Results of a Schering-Plough Corporation Phase II trial of SCH 530348, a novel oral thrombin receptor antagonist (TRA), were published today in The Lancet and demonstrated that the investigational antiplatelet compound met its primary endpoints of safety and tolerability.

12 Mar 2009

New drug derived from magnolia trees proves safe, tolerable in preventing blood clots

A new drug derived from magnolia trees appears to be able to uncouple two important functions of thrombin in blood clot formation and may offer a way to better control the potentially dangerous complications of bleeding and clot formation during procedures to open blocked coronary arteries, say researchers at the Duke Clinical Research Institute (DCRI).

12 Mar 2009

Vitamin C intake linked to lower risk of gout in men

Men with higher vitamin C intake appear less likely to develop gout, a painful type of arthritis, according to a report in the March 9 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

10 Mar 2009

Eating lots of vegetables reduces risk of prostate cancer

In the online edition of Molecular Nutrition and Food Research, Ruth Chan and collaborators provided a review on prostate cancer (CaP) and vegetable consumption.

8 Mar 2009

Serious flaws in study on vitamin C treatment in cancer

Serious flaws in a recent study, which concluded that high doses of vitamin C reduce the effectiveness of chemotherapeutic drugs in the treatment of cancer, are revealed in the current issue of Alternative and Complementary Therapies.

5 Mar 2009

Experimental microbicide containing natural compound provides protection in monkeys against simian version of HIV

An experimental microbicide containing a naturally occurring compound provides protection in monkeys against the simian version of HIV by diminishing immune responses to the virus, according to a study published Wednesday in the journal Nature, the Los Angeles Times reports.

5 Mar 2009

FDA accepts IND application for Tigris Pharmaceutical's GGTI-2418

Tigris Pharmaceuticals, Inc., has announced that its Investigational New Drug (IND) application for the Company's geranylgeranyltransferase inhibitor (GGTI-2418) has been accepted by the U.S. Food and Drug Administration.

4 Mar 2009

FDA clears Cellectar's IND application for lead drug candidate

Cellectar, Inc. has announced that the U.S. Food and Drug Administration (FDA) has cleared the Company's Investigational New Drug (IND) application for its (131)I-CLR1404 drug candidate for testing in patients with advanced solid malignancies.

3 Mar 2009

Aerovance starts trial of Aerovant for uncontrolled asthma

Aerovance Inc. has announced that it has received clearance from the U.S. Food and Drug Administration (FDA) and the U.K. Medicines and Healthcare products Regulatory Agency (MHRA) to initiate Aerovance's Phase IIb clinical trial, AeroTrial(TM), of inhaled dry powder Aerovant in patients with uncontrolled asthma.

3 Mar 2009

Study predicts when invasive species can travel more readily by air

A new study forecasts when climate factors such as temperature, humidity and rainfall will match at geographically distant airline departure and destination points, which could help to shuffle invasive species, and the diseases they may carry, across the globe along existing flight routes.

2 Mar 2009