Conjugation News and Research

RSS

U.S. PTO awards Endocyte patent for vitamin receptor binding anti-cancer agents

Officials at Endocyte Inc., a cancer drug discovery and development company, announced Tuesday (Oct. 27, 2009) that the company has been awarded a patent from the U.S. Patent and Trademark Office covering vitamin receptor binding anti-cancer agents.

28 Oct 2009

The effect of tea polyphenols on paracetamol-induced hepatotoxicity

Paracetamol is one of the most widely used, studied, and arguably the most notorious hepatotoxic drugs, which is safe at therapeutic doses but causes liver failure when overdosed.

21 Apr 2009

Paradigm shift in the regulation of immune response

Over the past decade various pieces of the puzzle how signal transmission controls immunity have been coming together.

20 Mar 2009

Axela introduces dotLab Amine Reactive Sensor

Axela Inc has introduced the dotLab Amine Reactive Sensor for stable covalent coupling of affinity reagents such as antibodies for use with the Axela dotLab System.

4 Mar 2009

Blocking mechanism found for antibiotic resistance in bacteria

It's as simple as A, T, G, C. Northwestern University scientists have exploited the Watson-Crick base pairing of DNA to provide a defensive tool that could be used to fight the spread of antibiotic resistance in bacteria -- one of the world's most pressing public health problems.

18 Dec 2008

Autonomous glial mechanism may drive circadian rhythms

Glial cells of the nervous system, once thought to function strictly as support cells for neurons, are now thought to actively modulate them.

2 Aug 2007

New weapon in the battle against antibiotic-resistant bacteria

Putting bacteria on birth control could stop the spread of drug-resistant microbes, and researchers at the University of North Carolina at Chapel Hill have found a way to do just that.

10 Jul 2007

Targeting key proteins of carcinogenesis

Misfolded and disused proteins are eliminated by a cellular shredder called the proteasome.

23 Jun 2007

Researchers develop way to calculate rate of gene transfer among bacteria in the environment

Scientists from the University of California-Davis recently developed a mathematical model of the rate of gene transfer among bacteria in the environment.

16 May 2007

Magnetic nanocrystals used to carry tumor-killing drugs

Imagine using a focused magnetic field to concentrate anticancer drugs in and around tumors, and then turning off the magnetic field so that the drugs then leave the body.

5 Mar 2007

Second-generation dendrimer disintegrates upon command

Dendrimers, highly branched, spherical polymers, have demonstrated their utility as drug and imaging agent delivery vehicles for use in detecting and treating cancer, with several dendrimer-based agents nearing human clinical trials.

29 Jan 2007

Self-illuminating quantum dots for in vivo imaging

Quantum dots have already proven themselves as powerful imaging probes that can enable researchers to track disease-related molecules inside cells and even within the body.

17 Jul 2006

Scientists have uncovered the structure of a network of proteins that help regulate the life cycle of cells

Scientists at Memorial Sloan-Kettering Cancer Center (MSKCC) have uncovered the structure of a network of proteins that help regulate the life cycle of cells. Understanding the network's physical layout is an important step toward learning its precise function, and in finding ways to correct flaws in the system that could lead to cancer.

2 Jun 2005

Cytogen Corporation and Dowpharma collaborate to create a targeted oncology product designed to treat prostate and other cancers

Under the agreement, Dowpharma's proprietary MeO-DOTA bifunctional chelant technology will be used to radiolabel Cytogen's prostate-specific membrane antigen (PSMA) antibody with a therapeutic radionuclide. PSMA is a protein highly expressed on the surface of prostate cancer cells and the neovasculature of many solid tumors.

10 May 2005

New way of transporting medicines into the brain

Dutch researcher Corine Visser investigated a new way of transporting medicines into the brain. Her approach made use of an iron transport system located on the blood-brain barrier. The smaller the medicine, the more easily it penetrates the brain.

13 Feb 2005