Craniofacial News and Research

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Discovery of new strain of bacteria could aid in developing effective oral probiotic

University of Florida Health researchers have identified a new strain of bacteria in the mouth that may keep bad bacteria in check -- and could lead to a way to prevent cavities using probiotics.The researchers say the findings could lead to the development of a supplement that patients could take orally to prevent cavities

11 Mar 2016

Researchers develop effective technique for studying high-arched palate using mouse model

Researchers from the laboratory of Paul Trainor, Ph.D., at the Stowers Institute of Medical Research have developed an effective and reliable technique for studying high-arched palate using a mouse model. The methodology could expand research into the genetic aspects of this craniofacial abnormality.

27 Feb 2016

3D planning and CAD/CAM techniques have potential for advances in plastic and reconstructive surgery

While used mainly in craniofacial reconstruction so far, 3D planning and CAD/CAM techniques have the potential for advances in practically every area of plastic and reconstructive surgery, according to the review by Drs. Miles J. Pfaff and Derek Steinbacher of Yale University.

27 Feb 2016

Rochester scientists identify stem cells capable of skull formation, craniofacial bone repair in mice

A team of Rochester scientists has, for the first time, identified and isolated a stem cell population capable of skull formation and craniofacial bone repair in mice--achieving an important step toward using stem cells for bone reconstruction of the face and head in the future, according to a new paper in Nature Communications.

1 Feb 2016

New NYUCD study explores how gene expression initiated in notochord

A new study by basic science researchers in the Department of Basic Science and Craniofacial Biology at New York University College of Dentistry sought to understand how gene expression is initiated in the notochord, the evolutionary and developmental precursor of the backbone.

29 Jan 2016

USC discoveries propose promising method to eliminate pain associated with tooth decay

Dual discoveries at USC propose a promising method to regrow nonliving hard tissue, lessening or even eliminating pain associated with tooth decay, which the National Institutes of Health calls the most prevalent chronic disease.

18 Nov 2015

UIC to develop and test outreach program to improve children’s oral health in Chicago

The University of Illinois at Chicago will develop and test an outreach program to reduce cavities in Chicago's low-income and minority infants and toddlers under a five-year, $5 million grant from the National Institutes of Health.

22 Sep 2015

New Penn Medicine research shows vital role of Esrp1 and Esrp2 genes in skin, organ development

Knocking out one or both crucial regulatory genes caused cleft lip, skin barrier defects, and a host of other developmental problems in mice, according to new research from the Perelman School of Medicine at the University of Pennsylvania, hinting that abnormalities in these molecular pathways could underlie many birth defects that are presently not well understood. The two closely related regulatory genes are active in the normal development of mammals and govern how RNAs produced from the genes are joined to make final versions of the encoded protein, a process called alternative splicing.

16 Sep 2015

CSUSM gains initial accreditation for Master of Science in Speech-Language Pathology program

California State University San Marcos has earned initial accreditation from the Council on Academic Accreditation (CAA) of the American Speech-Language Hearing Association for the Master of Science in Speech-Language Pathology (SLP) program.

9 Sep 2015

UA professor uses NSF grant to develop 3-D-printed biodegradable polymer scaffolds

Laboratory-engineered noses, jaws and ears. The stuff science fiction is made of is coming soon from a University of Akron lab. With a $390,000 NSF grant, Matthew Becker, UA professor of polymer science and biomedical engineering, is developing 3-D-printed biodegradable polymer scaffolds, the frameworks within which bone will grow, with the hope of changing the face of craniofacial reconstruction.

25 Aug 2015

New study reveals role of hydrogen sulfide gas in autoimmune disease

The immune system not only responds to infections and other potentially problematic abnormalities in the body, it also contains a built-in brake in the form of regulatory T cells, or Tregs. Tregs ensure that inflammatory responses don't get out of hand and do damage. In autoimmune diseases, sometimes these Treg cells don't act as they should.

12 Aug 2015

New computer-based system provides real-time feedback before and during facial transplant surgery

Following several years of research and collaboration, physicians and engineers at Johns Hopkins and Walter Reed National Military Medical Center say they have developed a computer platform that provides rapid, real-time feedback before and during facial transplant surgery, which may someday improve face-jaw-teeth alignment between donor and recipient.

30 Jul 2015

UF researchers develop smart mouth guard to detect teeth grinding

Researchers at the University of Florida have developed a smart mouth guard equipped with sensors that allow it to detect if you're grinding your teeth, tell your dentist and even help you stop doing it.

3 Jul 2015

Case report published on first use of 3D printed scaffold for periodontal tissue engineering

Today, the International and American Associations for Dental Research published a case report on the first application of a 3D printed scaffold for periodontal tissue engineering in a human patient, along with a review of 3D printing for oral and craniofacial tissue engineering.

30 Jun 2015

Houston Methodist Hospital and MD Anderson Cancer Center surgeons successfully perform multi-organ transplant

Surgical teams from Houston Methodist Hospital and The University of Texas MD Anderson Cancer Center successfully transplanted, for the first time, a scalp and skull while performing kidney and pancreas transplants.

5 Jun 2015

Penn State to receive $1.84 million over five years to explore craniosynostosis

Penn State will receive $1.84 million over five years as a subcontract on a National Institutes of Health grant through the Icahn School of Medicine at Mount Sinai Hospital, New York, N.Y., to explore craniosynostosis, a birth defect that includes facial and cranial dysmorphology.

28 May 2015

Stem cell treatment repairs birth defect, provides facial regeneration for people suffering traumatic injury

Researchers have pinpointed a primary cause of a rare skull disorder in infants, and the discovery could help wounded soldiers, car-wreck victims and other patients recover from disfiguring facial injuries.

23 Apr 2015

New method for measuring genetic variability may help identify patients with aggressive cancers

A new method for measuring genetic variability within a tumor might one day help doctors identify patients with aggressive cancers that are more likely to resist therapy, according to a study led by researchers now at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

17 Apr 2015

Setting standard of care for children born with cleft lip and palate

Representatives from Texas Children's Hospital joined an international group of medical professionals, patients and parents to determine a standard set of outcome measures for children born with cleft lip and palate.

9 Apr 2015

NYUCD receives NIH grant to develop POC test to detect HIV antibodies and viral RNA

New York University College of Dentistry has received a sub-award in the amount of $335,000 from a Small Business Innovation Research (SBIR) Phase II grant from the National Institutes of Health to complete the development of a fully automated self-confirming assay that can simultaneously detect HIV/AIDS antibodies and viral RNA from the AIDS virus in a single specimen.

29 Mar 2015