Craniofacial News and Research

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Two genetic factors strongly associated with non-syndromic sagittal craniosynostosis

An international team of geneticists, pediatricians, surgeons and epidemiologists from 23 institutions across three continents has identified two areas of the human genome associated with the most common form of non-syndromic craniosynostosis ― premature closure of the bony plates of the skull.

18 Nov 2012

Oral verrucous lesions need special diagnostic attention

Care should be taken to diagnose oral verrucous lesions accurately according to their nature, behavior, and malignant potential, and should be differentiated from grade I squamous cell carcinoma, suggest Indian researchers.

8 Nov 2012

Heart disease risk factors widespread among Hispanic/Latino adults in the U.S.

Hispanic Community Health Study/Study of Latinos (HCHS-SOL) - which will be presented at the American Heart Association Annual Meeting in Los Angeles on Nov. 5 and published in the Nov. 7 issue of the Journal of the American Medical Association (JAMA) - finds heart disease risk factors are widespread among Hispanic/Latino adults in the United States.

7 Nov 2012

John Wiley & Sons launches Molecular Genetics & Genomic Medicine

John Wiley & Sons, Inc., today announced the launch of Molecular Genetics & Genomic Medicine (MGGM), a new Wiley Open Access journal. Under the leadership of Editor-in-Chief Dr. Maximilian Muenke, the journal will provide rapid dissemination of high-quality research in all areas of human, medical and molecular genetics.

6 Nov 2012

Four transcription factor genes control processes related to heart and head muscle formation

A group of researchers in Israel, the United States and other nations have made important advances in the rapidly-expanding field of "regenerative medicine," outlining for the first time connections in genetic regulation that normally prevent birth defects in heart and facial muscles.

30 Oct 2012

Daily whole body vibration may combat prediabetes in adolescents

Daily sessions of whole-body vibration may combat prediabetes in adolescents, dramatically reducing inflammation, average blood glucose levels and symptoms such as frequent urination, researchers report.

20 Oct 2012

NYU professor to analyze how older adults overcome barriers to accessing oral health care services

Dr. Mary E. Northridge, assistant professor of epidemiology and health promotion at the New York University College of Dentistry, has been awarded a five-year, $3.7 million grant from the National Institute of Dental and Craniofacial Research (NIDCR) and the Office of Behavioral and Social Sciences Research (OBSSR), of the National Institutes of Health (NIH), to analyze how racial and ethnic older adults living in underserved urban communities in NYC overcome barriers to accessing oral health care services.

17 Oct 2012

Salivary-biomarker approach can identify individuals at future risk of PTSD, depression

Each year, more than a million Americans are at-risk of developing serious mental health problems after experiencing a terrifying event or serious physical injury. Once manifested, these psychiatric illnesses, such as post-traumatic stress disorder and depression, can be extremely crippling and difficult to treat and are a leading cause of disability in civilian, military and minority populations.

10 Oct 2012

Early bone graft plus rhinoplasty significantly improves facial esthetics in UCLP

The facial esthetic of children with unilateral cleft lip and palate is significantly improved with early alveolar bone grafting alongside rhinoplasty, versus leaving the procedure until the child is older, study findings show.

3 Oct 2012

Mammalian target of rapamycin inhibitors can prevent radiation-induced tissue damage

Radiation therapy is one of the most widely used cancer treatments, but it often damages normal tissue and can lead to debilitating conditions. A class of drugs known as mammalian target of rapamycin (mTOR) inhibitors can prevent radiation-induced tissue damage in mice by protecting normal stem cells that are crucial for tissue repair, according to a preclinical study published by Cell Press in the September issue of the journal Cell Stem Cell.

7 Sep 2012

Study examines environmental and biological impacts on children with cleft lip and palate

Children with cleft lip and/or palate encounter different challenges throughout the course of their development. Both environmental and biological factors play a role, and can affect speech, academic performance, and behavior. Research has shown varying influences, including the type of cleft, gender, and age, affecting outcomes.

16 Aug 2012

Cancer patients with xerostomia can benefit from regenerative research

Biologists, surgical oncologists and regenerative medicine specialists from Rice University, the University of Delaware and the Christiana Care Health System in Wilmington, Del., have begun a four-year program aimed at using cells to grow whole salivary glands that can replace those destroyed by cancer radiation therapy.

16 Aug 2012

Prestigious $2.5M NIH grant to continue work into creation of artificial salivary glands

A research team at the Helen F. Graham Cancer Center at Christiana Care Health System and the Center for Translational Cancer Research performs a key role in a prestigious National Institutes of Health research project grant of $2.5 million to continue groundbreaking work into the creation of artificial salivary glands.

13 Aug 2012

Link between skeletal development and Fraser syndrome deafness in mammals

Using mutant zebra fish, researchers studying the earliest formation of cartilage of the mouth believe they may have gotten a look at a mechanism involved in a genetic defect linked to Fraser syndrome deafness in humans.

1 Aug 2012

Stem cell therapy holds promise for craniofacial bone repair

In the first human study of its kind, researchers found that using stem cells to re-grow craniofacial tissues-mainly bone-proved quicker, more effective and less invasive than traditional bone regeneration treatments.

31 Jul 2012

Chewing gum may relieve the pain of braces

Young adolescents and teens with fixed orthodontic appliances who chew gum report significantly less pain and impact of their braces than their peers who do not chew gum, report researchers from Sheffield in the UK.

23 Jul 2012

Scientists discover two key epigenetic regulating genes that govern stem cell differentiation

The ability to control whether certain stem cells ultimately become bone cells holds great promise for regenerative medicine and potential therapies aimed at treating metabolic bone diseases. Now, UCLA School of Dentistry professor and leading cancer scientist Dr. Cun-Yu Wang and his research team have made a significant breakthrough in that direction. The scientists have discovered two key epigenetic regulating genes that govern the cell-fate determination of human bone marrow stem cells.

10 Jul 2012

Researchers develop new silk-based stabilizer for vaccines and antibiotics

Researchers funded by the National Institutes of Health have developed a new silk-based stabilizer that, in the laboratory, kept some vaccines and antibiotics stable up to temperatures of 140 degrees Fahrenheit.

10 Jul 2012

PHF21A gene plays a big role in Potocki-Shaffer syndrome

A gene whose mutation results in malformed faces and skulls as well as mental retardation has been found by scientists.

6 Jul 2012

UCLA School of Dentistry receives NIH grant to create comprehensive research training program

In recent years, faculty at the UCLA School of Dentistry have been expanding the traditional boundaries of dentistry through groundbreaking multidisciplinary research that has led to major advances in everything from stem cell science to saliva diagnostics. Now, a $5 million grant from the National Institutes of Health's National Institute of Dental and Craniofacial Research will allow the school to continue these pioneering efforts by creating a comprehensive research training program to help cultivate the next generation of dentist-scientists and oral health researchers.

4 Jul 2012

Craniofacial News and Research

Two genetic factors strongly associated with non-syndromic sagittal craniosynostosis

Oral verrucous lesions need special diagnostic attention

Heart disease risk factors widespread among Hispanic/Latino adults in the U.S.

John Wiley & Sons launches Molecular Genetics & Genomic Medicine

Four transcription factor genes control processes related to heart and head muscle formation

Daily whole body vibration may combat prediabetes in adolescents

NYU professor to analyze how older adults overcome barriers to accessing oral health care services

Salivary-biomarker approach can identify individuals at future risk of PTSD, depression

Early bone graft plus rhinoplasty significantly improves facial esthetics in UCLP

Mammalian target of rapamycin inhibitors can prevent radiation-induced tissue damage

Study examines environmental and biological impacts on children with cleft lip and palate

Cancer patients with xerostomia can benefit from regenerative research

Prestigious $2.5M NIH grant to continue work into creation of artificial salivary glands

Link between skeletal development and Fraser syndrome deafness in mammals

Stem cell therapy holds promise for craniofacial bone repair

Chewing gum may relieve the pain of braces

Scientists discover two key epigenetic regulating genes that govern stem cell differentiation

Researchers develop new silk-based stabilizer for vaccines and antibiotics

PHF21A gene plays a big role in Potocki-Shaffer syndrome

UCLA School of Dentistry receives NIH grant to create comprehensive research training program

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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