Critical Care News and Research

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Primary ciliary dyskinesia linked to heterotaxy

The same genetic defect that causes a rare respiratory disease may also lead to some types of congenital heart disease, according to a study from the University of North Carolina at Chapel Hill School of Medicine.

14 Jun 2007

Talcum powder stunts cancer growth

Talcum powder has been used for generations to soothe babies diaper rash and freshen women's faces.

8 Jun 2007

AMPAKINE drugs may provide protection from drug-induced respiratory depression

Drug-induced respiratory depression is a life-threatening condition caused by analgesic, hypnotic, and anesthesia medications.

5 Jun 2007

Tuberculosis therapy in HIV-infected patients

In a retrospective study of 700 patients with culture-positive tuberculosis (TB), relapse rates were found to be significantly higher in HIV-infected patients compared to HIV-uninfected patients following a rifamycin-based regimen.

3 Jun 2007

Research explains why those with obstructive sleep apnea are at higher risk for cardiovascular disease

Researchers have found that patients with obstructive sleep apnea (OSA) have higher levels of a type of dead cells (apoptotic cells) from the lining (endothelium) of their blood vessels circulating in their bloodstream than people who do not have OSA.

3 Jun 2007

Gene expression patterns predict rapid decline in idiopathic pulmonary fibrosis patients

Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease typically characterized by the slow but progressive onset of shortness of breath or cough.

1 Jun 2007

Mercury's link to heart disease

Heavy metals and other toxins have been linked to many human diseases, but determining exactly how they damage the body remains a mystery in many cases.

1 Jun 2007

Obese people more likely to have persistent or severe persistent asthma

A new study presented at the American Thoracic Society 2007 International Conference finds that obese people are significantly more likely to have persistent or severe persistent asthma than their thinner counterparts.

24 May 2007

Early identification and aggressive treatment of sepsis has the potential to improve outcomes

More than 215,000 people will die of sepsis in the United States each year, more than 750,000 will require hospital treatment, and the costs will be nearly $17 billion.

17 May 2007

Single dose of vitamin D may be enough to boost the immune system to fight against tuberculosis

Their findings came from a study that identified an extraordinarily high incidence of vitamin D deficiency amongst those communities in London most at risk from the disease, which kills around two million people each year.

16 May 2007

Low-birth-weight babies at significantly greater risk for early respiratory symptoms

Through age 5, children born at full term with low birth weight show significantly greater risk for developing respiratory symptoms, including wheezing, coughing and pulmonary infections, according to a large longitudinal study on birth weight and development.

16 May 2007

Atypical pathogen treatment vital in hospitalized community-acquired pneumonia patients

Hospitalized patients with community-acquired pneumonia (CAP) who received treatment regimens against atypical disease-causing pathogens reached clinical stability quicker, had fewer days of hospitalization, and had lower mortality rates as a result of their disease, according to a large new study.

16 May 2007

FDA approves Dey, L.P.'s NDA for chronic obstructive pulmonary disease inhalation solution

Dey, L.P. has announced that the Food and Drug Administration (FDA) has approved its New Drug Application (NDA) for Perforomist (formoterol fumarate) Inhalation Solution for long-term, twice-daily maintenance treatment of bronchoconstriction for emphysema and chronic bronchitis, also known as Chronic Obstructive Pulmonary Disease (COPD).

15 May 2007

Simple procedural change may reduce cardiac arrests outside pediatric ICUs

A simple procedural change may significantly reduce cardiopulmonary arrests outside a pediatric hospital's intensive care unit, according to a study reported at the American Heart Association's 8th Scientific Forum on Quality of Care and Outcomes Research in Cardiovascular Disease and Stroke.

11 May 2007

Novel therapies to prevent metastasis

In a study that could point to novel therapies to prevent cancer spread, or metastasis, researchers at the University of California, San Diego (UCSD) School of Medicine have targeted a sugar that supports blood vessel growth in the tumor.

8 May 2007

Alcohol-based handrubs can improve hygiene in hospitals

Giving health care workers easy access to alcohol-based handrubs can improve hygiene in hospitals, a study published in the Online Open Access journal Critical Care suggests.

4 May 2007

FDA approves new indication for FRAGMIN for the extended treatment of symptomatic venous thromboembolism

The U.S. Food and Drug Administration (FDA) has approved a new indication for FRAGMIN (dalteparin sodium injection), for the extended treatment of symptomatic venous thromboembolism (VTE) to reduce the recurrence of VTE in patients with cancer.

4 May 2007

Infliximab fails to improve chronic obstructive pulmonary disease symptoms

A promising anti-inflammatory drug failed to improve symptoms of moderate to severe chronic obstructive pulmonary disease, or COPD, in a large, multi-center trial.

2 May 2007

Evidence of very early onset defective bone mineralization in the lumbar spine revealed in children with cystic fibrosis

In a study of children with cystic fibrosis, French researchers found evidence of very early onset defective bone mineralization in the lumbar spine that was not caused by either nutritional status or lung disease.

2 May 2007

Web-based disease management program improves outcomes for low-income black students

Low-income African-American high school students with asthma who participated in a specially-designed, web-based disease management program reported fewer days and nights with symptoms, fewer school days missed, fewer days of restricted activity, and less hospitalization for asthma during a 12-month follow-up period, as compared to non-participating asthmatic students.

2 May 2007

Critical Care News and Research

Primary ciliary dyskinesia linked to heterotaxy

Talcum powder stunts cancer growth

AMPAKINE drugs may provide protection from drug-induced respiratory depression

Tuberculosis therapy in HIV-infected patients

Research explains why those with obstructive sleep apnea are at higher risk for cardiovascular disease

Gene expression patterns predict rapid decline in idiopathic pulmonary fibrosis patients

Mercury's link to heart disease

Obese people more likely to have persistent or severe persistent asthma

Early identification and aggressive treatment of sepsis has the potential to improve outcomes

Single dose of vitamin D may be enough to boost the immune system to fight against tuberculosis

Low-birth-weight babies at significantly greater risk for early respiratory symptoms

Atypical pathogen treatment vital in hospitalized community-acquired pneumonia patients

FDA approves Dey, L.P.'s NDA for chronic obstructive pulmonary disease inhalation solution

Simple procedural change may reduce cardiac arrests outside pediatric ICUs

Novel therapies to prevent metastasis

Alcohol-based handrubs can improve hygiene in hospitals

FDA approves new indication for FRAGMIN for the extended treatment of symptomatic venous thromboembolism

Infliximab fails to improve chronic obstructive pulmonary disease symptoms

Evidence of very early onset defective bone mineralization in the lumbar spine revealed in children with cystic fibrosis

Web-based disease management program improves outcomes for low-income black students

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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