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New therapeutic alternative found for children suffering from Ewing's sarcoma

A research consortium made up of the Virgen del Rocio hospital in Seville, Sant Joan de Deu and the Bellvitge Biomedical Research Institute in Barcelona, has found a new therapeutic alternative for children who suffer from a malignant pediatric tumor bone and soft tissue called Ewing's sarcoma.

7 Jul 2015

Newcastle University scientists document action spectrum of ultraviolet damage in skin cells

Scientists at Newcastle University have documented for the first time the DNA damage which can occur to skin across the full range of ultraviolet radiation from the sun providing an invaluable tool for sun-protection and the manufacturers of sunscreen.

27 Jun 2015

Montefiore dermatologist debunks myths regarding skin care, offers information to help people enjoy summer days

As many begin to spend long summer days outside, it's crucial to have the right information about skin protection and the dangers of sun exposure. Today, Montefiore dermatologist Dr. Holly Kanavy debunks many widely-shared myths regarding skin care and offers accurate information to help people enjoy the outdoors this summer while preserving their skin.

18 Jun 2015

Researchers reveal that Helicobacter pylori infection can lead to gastric cancer

Around half of the global population is chronically infected with the stomach bacterium Helicobacter pylori, almost 1 percent of whom go on to develop gastric adenocarcinoma, one of the deadliest forms of cancer. Usually it takes many decades for the cancer to develop, making it difficult to pinpoint exactly how it is linked to an infection.

17 Jun 2015

UK dermatologist explains the facts on vitamin D and sun exposure

Sometimes it can be hard to weigh up the benefits of vitamin D versus sun exposure. We talk to Dr Anjali Mahto, Consultant Dermatologist & British Skin Foundation Spokesperson who explains.

16 Jun 2015

Certain ARID1a mutations sensitize some tumors to PARP inhibitor drugs

Mutations in ARID1a, which are common in many cancer types, disrupt DNA damage repair in cancer cells, allowing the cancer to progress. This gene may also be an Achilles' heel when treating certain tumors, according to a team of researchers at The University of Texas MD Anderson Cancer Center.

12 Jun 2015

Findings point to new therapy against prostate and other cancers

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have found that a drug candidate with anticancer potential can be activated by one of the body's natural responses to cellular stress. Once activated, the agent can kill prostate cancer cells.

11 Jun 2015

Cell fusion triggers multiple genetic changes that convert normal cells to cancer cells

Although there is no one established universal cause of cancer, genetic changes are central to its development. The accumulation of spontaneous genetic changes, or mutations, that occur when cells divide can be hastened by exposure to carcinogens such as cigarette smoke (lung cancer) and infectious agents such as the papillomavirus (cervical cancer).

9 Jun 2015

Finding could help researchers develop new methods to prevent cognitive decline in Alzheimer's disease

The process that allows our brains to learn and generate new memories also leads to degeneration as we age, according to a new study by researchers at MIT.

5 Jun 2015

Scientists identify novel mechanism that can reorganize cell's genetic architecture to promote senescence

Senescence, a phenomenon in which cells cease to divide and grow, can be caused by everything from natural DNA damage to treatment with chemotherapy. However, several mechanisms allow for cells to bypass senescence and grow out of control, eventually becoming cancerous.

3 Jun 2015

ASCO 2015: UH Seidman Cancer Center researchers present data from several new studies

Researchers from University Hospitals Case Medical Center Seidman Cancer Center and Case Western Reserve University School of Medicine will present data from several new studies, including a study evaluating a potential novel combination treatment for cancer patients with advanced solid tumors and a first-of-its-kind analysis of gene mutations in small cell lung cancer (SCLC), at the 51st American Society for Clinical Oncology (ASCO) Annual Meeting in Chicago.

1 Jun 2015

Process of aging could be delayed in human cell lines

Can the process of aging be delayed or even reversed? Research led by specially appointed Professor Jun-Ichi Hayashi from the University of Tsukuba in Japan has shown that, in human cell lines at least, it can. They also found that the regulation of two genes involved with the production of glycine, the smallest and simplest amino acid, is partly responsible for some of the characteristics of aging.

1 Jun 2015

New clinical studies on Myriad Genetics myChoice HRD companion diagnostic test presented at ASCO 2015

Myriad Genetics, Inc. today announced new clinical studies on its myChoice HRD companion diagnostic test at the 2015 American Society of Clinical Oncology annual meeting being held in Chicago, Ill.

1 Jun 2015

Myriad Genetics announces new clinical studies on myChoice HRD companion diagnostic test at ASCO 2015

Myriad Genetics, Inc. today announced new clinical studies on its myChoice HRD companion diagnostic test at the 2015 American Society of Clinical Oncology annual meeting being held in Chicago, Ill.

30 May 2015

Study reveals new molecular mechanism that helps protect genome from harmful effect of UV radiations

Researchers have uncovered a new molecular mechanism whereby human cells protect their genome from the detrimental effect of UV radiation and govern DNA replication in cellular mitosis, which, when it malfunctions, leads to harmful results.

29 May 2015

Scientists uncover role of HTRA3 protease in Cockayne syndrome

Scientists from the Institut Pasteur and CNRS, in collaboration with scientists from the Institut Gustave Roussy and CEA, have succeeded in restoring normal activity in cells isolated from patients with the premature aging disease Cockayne syndrome. They have uncovered the role played in these cells by an enzyme, the HTRA3 protease.

22 May 2015

Leeds scientists examine benefits of hyaluronic acid in helping improve IVF success rates

Scientists from the University of Leeds are investigating whether a molecule usually found in moisturisers and skin creams could improve IVF success rates in the UK.

20 May 2015

Smoking-related DNA damage can be detected in cheek swabs

DNA damage caused by smoking can be detected in cheek swabs, finds research published today in JAMA Oncology. The study provides evidence that smoking induces a general cancer program that is also present in cancers which aren't usually associated with it - including breast and gynaecological cancers.

15 May 2015

Scientists identify new molecules that destroy cancer cells, save healthy ones

Researchers have identified new molecules that kill cancer cells while protecting healthy cells and that could be used to treat a variety of different cancers. The research shines a light on what happens to cells at the moment they become cancerous.

15 May 2015

Discovery could help identify molecules that selectively target cancer cells

A new family of molecules that kill cancer cells and protect healthy cells could be used to treat a number of different cancers, including cervical, breast, ovarian and lung cancers. Research published in EBioMedicine shows that as well as targeting and killing cancer cells, the molecules generate a protective effect against toxic chemicals in healthy cells.

13 May 2015

DNA Damage News and Research

New therapeutic alternative found for children suffering from Ewing's sarcoma

Newcastle University scientists document action spectrum of ultraviolet damage in skin cells

Montefiore dermatologist debunks myths regarding skin care, offers information to help people enjoy summer days

Researchers reveal that Helicobacter pylori infection can lead to gastric cancer

UK dermatologist explains the facts on vitamin D and sun exposure

Certain ARID1a mutations sensitize some tumors to PARP inhibitor drugs

Findings point to new therapy against prostate and other cancers

Cell fusion triggers multiple genetic changes that convert normal cells to cancer cells

Finding could help researchers develop new methods to prevent cognitive decline in Alzheimer's disease

Scientists identify novel mechanism that can reorganize cell's genetic architecture to promote senescence

ASCO 2015: UH Seidman Cancer Center researchers present data from several new studies

Process of aging could be delayed in human cell lines

New clinical studies on Myriad Genetics myChoice HRD companion diagnostic test presented at ASCO 2015

Myriad Genetics announces new clinical studies on myChoice HRD companion diagnostic test at ASCO 2015

Study reveals new molecular mechanism that helps protect genome from harmful effect of UV radiations

Scientists uncover role of HTRA3 protease in Cockayne syndrome

Leeds scientists examine benefits of hyaluronic acid in helping improve IVF success rates

Smoking-related DNA damage can be detected in cheek swabs

Scientists identify new molecules that destroy cancer cells, save healthy ones

Discovery could help identify molecules that selectively target cancer cells

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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