DNA Methylation News and Research

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DNA methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the most well characterized epigenetic mechanism.

Researchers aim to identify gene-lifestyle interactions that contribute to cardiometabolic disease risk

Researchers at Washington University School of Medicine in St. Louis have received a four-year, $8.8 million grant to ramp up research aimed at unraveling how an individual's risks of cardiometabolic diseases, such as heart disease and Type 2 diabetes, are influenced by the interaction of specific genes with demographic and lifestyle factors.

11 Aug 2021

Study uncovers epigenetic mechanism that mediates a link between fetal conditions and later health

A study at Tampere University has identified one possible epigenetic mechanism through which the conditions at conception may affect the health of an individual in later life.

10 Aug 2021

Researchers discover DNA signatures associated with heart disease risk

A new study identifies DNA signatures associated with risk for cardiovascular disease, a discovery that could lead to opportunities for clinical intervention years before symptoms manifest.

4 Aug 2021

Innovative strategy for early diagnosis of schizophrenia

An innovative strategy that analyzes a region of the genome offers the possibility of early diagnosis of schizophrenia, reports a team led by researchers at Baylor College of Medicine.

3 Aug 2021

New discovery provides clues to elucidate the pathogenesis of muscle diseases

A research collaboration based in Kumamoto University, Japan has discovered that muscles and the resident stem cells (satellite cells) responsible for muscle regeneration retain memory of their location in the body.

6 Jul 2021

Researchers unravel mechanisms that produce individualized metabolism in leukemia

A research collaboration based in Kumamoto University (Japan) has shown that lysine-specific demethylase 1 (LSD1), an enzyme involved in gene expression, produces individualized metabolism depending on the type of acute myeloid leukemia cells.

6 Jul 2021

Castration of male sheep slows DNA aging

Most of us are familiar with the fact that women live longer than men. But fellas, if we told you there was one thing that could be done to increase your lifespan, would you do it?

6 Jul 2021

Study shows how epigenetic factors modulate the risk of type 1 diabetes

Genetics plays a major role in determining a person’s risk of developing type 1 diabetes, but environmental and lifestyle factors are also important. In an article recently published in Chinese Medical Journal, a team of researchers explore the interplay of genetic and environmental factors by summarizing the literature on type 1 diabetes and epigenetics—the study of how gene expression patterns can be modified.

18 Jun 2021

Study provides treatment options for children with average risk medulloblastoma

Medulloblastoma is a rare but devastating childhood brain cancer. This cancer can spread through the spinal fluid and be deposited elsewhere in the brain or spine.

11 Jun 2021

Study reveals new insights into how genes are regulated in dementia

The largest study of its kind has unveiled new insights into how genes are regulated in dementia, including discovering 84 new genes linked to the disease.

10 Jun 2021

Research clarifies neuron-specific DNA methylation changes and characteristics in bipolar disorder

A research collaboration based in Kumamoto University, Japan has revealed the DNA methylation status of gene transcriptional regulatory regions in the frontal lobes of patients with bipolar disorder (BD).

9 Jun 2021

Healthy habits of pregnancy – latest science show maternal habits affect pregnancy success

Four new studies investigating the effects of supplements, eating habits and physical activity and how they can affect various aspects of health during pregnancy are being presented at NUTRITION 2021 LIVE ONLINE.

7 Jun 2021

Epigenetic regulation affects the 3D structure of genome

All the cells of an organism share the same DNA sequence, but their functions, shapes or even lifespans vary greatly. This happens because each cell "reads" different chapters of the genome, thus producing alternative sets of proteins and embarking on different paths.

3 Jun 2021

Molecular subtype of cancer preferentially affects people with Indigenous ancestry

Oncotarget published "Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry" which reported that contrasting with this pattern, the age structure of HCC in Andean people displays a bimodal distribution with half of the patients developing HCC in adolescence and early adulthood.

2 Jun 2021

Study: Specific diet, lifestyle interventions may reverse epigenetic aging in healthy adult males

Aging published "Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial" which reported on a randomized controlled clinical trial conducted among 43 healthy adult males between the ages of 50-72.

28 May 2021

Plastic chemicals can induce changes in gene that is vital for neurological development

The chemical bisphenol F (found in plastics) can induce changes in a gene that is vital for neurological development. This discovery was made by researchers at the universities of Uppsala and Karlstad, Sweden.

20 May 2021

Machine learning technique detects epigenetic drivers of cancers

Scientists have made major advances in understanding and developing treatments for many cancers by identifying genetic mutations that drive the disease.

10 May 2021

PAS 2021: Plenary session on prenatal environmental contaminants and childhood disease

A state of the art plenary session during the Pediatric Academic Societies 2021 Virtual Meeting discussed prenatal environmental contaminants and childhood disease, and the latest evidence for epigenetic mechanisms associated with transgenerational disease and public policy implications.

5 May 2021

Field of mathematics reveals a potential gene that causes acute lymphoblastic leukemia

Using a widely known field of mathematics designed mainly to study how digital and other forms of information are measured, stored and shared, scientists at Johns Hopkins Medicine and Johns Hopkins Kimmel Cancer Center say they have uncovered a likely key genetic culprit in the development of acute lymphoblastic leukemia (ALL).

21 Apr 2021

Novel CRISPR-based technology may lead to powerful epigenetic therapies

Scientists have figured out how to modify CRISPR's basic architecture to extend its reach beyond the genome and into what's known as the epigenome -- proteins and small molecules that latch onto DNA and control when and where genes are switched on or off.

17 Apr 2021

DNA Methylation News and Research

Further Reading

Researchers aim to identify gene-lifestyle interactions that contribute to cardiometabolic disease risk

Study uncovers epigenetic mechanism that mediates a link between fetal conditions and later health

Researchers discover DNA signatures associated with heart disease risk

Innovative strategy for early diagnosis of schizophrenia

New discovery provides clues to elucidate the pathogenesis of muscle diseases

Researchers unravel mechanisms that produce individualized metabolism in leukemia

Castration of male sheep slows DNA aging

Study shows how epigenetic factors modulate the risk of type 1 diabetes

Study provides treatment options for children with average risk medulloblastoma

Study reveals new insights into how genes are regulated in dementia

Research clarifies neuron-specific DNA methylation changes and characteristics in bipolar disorder

Healthy habits of pregnancy – latest science show maternal habits affect pregnancy success

Epigenetic regulation affects the 3D structure of genome

Molecular subtype of cancer preferentially affects people with Indigenous ancestry

Study: Specific diet, lifestyle interventions may reverse epigenetic aging in healthy adult males

Plastic chemicals can induce changes in gene that is vital for neurological development

Machine learning technique detects epigenetic drivers of cancers

PAS 2021: Plenary session on prenatal environmental contaminants and childhood disease

Field of mathematics reveals a potential gene that causes acute lymphoblastic leukemia

Novel CRISPR-based technology may lead to powerful epigenetic therapies

DNA Methylation eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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