DNA Methylation News and Research

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DNA methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the most well characterized epigenetic mechanism.

Facial recognition algorithms show genetic similarities in genetically unrelated look-alike humans

In a new study, researchers identified look-alike humans who were genetically unrelated using facial recognition (FR) algorithms for multi-omics studies.

25 Aug 2022

Strong facial similarity in people is linked with shared genetic variants

A collection of photos of genetically unrelated lookalikes, along with DNA analysis, revealed that strong facial similarity is associated with shared genetic variants.

23 Aug 2022

BCG vaccine produces a "trained immunity response" which lasts more than a year

The immune boosting benefits of a tuberculosis vaccine can be seen in infants more than one year after vaccination, according to a new study.

8 Aug 2022

Elevated insulin resistance, advanced cell aging associated with childhood poverty

Black adolescents who lived in poverty and were less optimistic about the future showed accelerated aging in their immune cells and were more likely to have elevated insulin resistance at ages 25-29, researchers found.

25 Jul 2022

Tissue nanotransfection technology can serve as a non-viral, topical, gene-editing delivery device, research shows

The Indiana Center for Regenerative Medicine and Engineering (ICRME) at Indiana University School of Medicine is home to tissue nanotransfection (TNT) regenerative medicine technology that achieves functional tissue reprogramming in the live body.

19 Jul 2022

New high-throughput genomic array offers an in-depth view of the mouse epigenome

A new high-throughput genomic array offers an unprecedented look into the mouse epigenome, giving researchers an in-depth view into the basis of health and disease in a vital model organism.

13 Jul 2022

Damon Runyon Cancer Research Foundation names five new Damon Runyon Clinical Investigators

The Damon Runyon Cancer Research Foundation has named five new Damon Runyon Clinical Investigators.

6 Jul 2022

Chemical-based sequencing method to efficiently study DNA methylation

One way cells can control the activities of their genes is by adding small chemical modifications to the DNA that determine which genes are turned on or off.

1 Jul 2022

HIV accelerates epigenetic aging soon after initial HIV infection

HIV has an "early and substantial" impact on aging in infected people, accelerating biological changes in the body associated with normal aging within just two to three years of infection, according to a study by UCLA researchers and colleagues.

1 Jul 2022

Epigenome-wide DNA methylation patterns in convalescent COVID-19 subjects

Researchers investigated the epigenetic rewiring of odor perception in SARS-CoV-2-infected cells.

29 Jun 2022

Researchers identify an epigenetic signature associated to the development of MIS-C after COVID-19

Researchers from the Cancer Epigenetics group led by Dr. Manel Esteller at the Josep Carreras Leukaemia Research Institute and Dr. Aurora Pujol, from the Bellvitge Biomedical Research Institute, have identified an epigenetic signature associated to the development of the Multisystem Inflammatory Syndrome in Children (MIS-C) after a SARS-CoV-2 virus infection.

27 Jun 2022

UiO researchers find 13 special genes related to epigenetic changes in cancer samples

Abnormal epigenetic changes are observed in the development of multiple types of cancer. Researchers at Centre for Molecular Medicine Norway (UiO) found 13 special genes linked to epigenetic changes in cancer samples.

16 Jun 2022

Diet supplemented with or deficient in methionine affects gene expression related to liver cell fat metabolism

Having shown that diet can influence gene expression, science is starting to find out more about how this happens.

15 Jun 2022

Study identifies an epigenetic regulator that suppresses pathogenic events in rheumatoid arthritis

Rheumatoid arthritis (RA) is characterized by chronic inflammation of synovium, eventually leading to joint destruction. Epigenetic alteration (the mechanism of gene expression regulation without DNA sequence changes), such as low levels of DNA methylation, is one of the factors which worsens the RA state.

8 Jun 2022

Study finds striking epigenetic differences in the airway cells of adult children born to asthmatic mothers

Asthma is a chronic condition that affects 25 million people in the United States. Having a mother with asthma is an important risk factor and a new study may explain why.

6 Jun 2022

Epigenetic markers associated with different risks of developing complications in type 2 diabetes

A new study by researchers at Lund University supports the notion that patients with type 2 diabetes patient should be divided into subgroups and given individualized treatment.

25 May 2022

Potential therapeutic target discovered for pancreatic ductal adenocarcinoma tumors

Northwestern Medicine investigators have discovered a potential therapeutic target for the most common type of pancreatic cancer, according to a study published in Developmental Cell.

19 May 2022

New drug inhibits growth of the most aggressive meningiomas

When a specific non-metastatic brain tumor — a meningioma — recurs after surgery and radiation treatment, a patient is normally out of options. No drugs are approved for these aggressive tumors, which occur in up to 20 percent of cases and can lead to patient disability or even death.

16 May 2022

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

An international research group led by Professor Toru Takumi (Senior Visiting Scientist, RIKEN Center for Biosystems Dynamics Research) and Researcher Chia-wen Lin at Kobe University Graduate School of Medicine has shown that idiopathic autism is caused by epigenetic abnormalities in hematopoietic cells during fetal development, which results in immune dysregulation in the brain and gut.

2 May 2022

Evidence of accelerated epigenetic age in SARS-CoV-2-positive patients

Researchers assessed the epigenetic aging in COVID-19 patients and its impact on COVID-19 severity by a genome-wide deoxyribonucleic acid methylation profiling analysis.

27 Apr 2022