Daughter Cell News and Research

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American scientists synthesize glycopolymers that prolong lifetime of healthy cells

Glycoproteins such as the mucins are assumed to be heavily involved in oncogenesis and metastasic spread. They are part of a strategy developed by malignant cells to resist or dodge the cell death machinery specialized for cells that show insufficient signaling through adhesions.

28 Nov 2015

Stem-cell scientists discover new view of how human blood is made

Stem-cell scientists led by Dr. John Dick have discovered a completely new view of how human blood is made, upending conventional dogma from the 1960s.

6 Nov 2015

Study could help mitigate effects of ageing on blood stem cells, promote new therapies for anaemia

A research conducted by Juan Méndez, Head of the DNA Replication Group of the Spanish National Cancer Research Centre (CNIO), sheds light on the molecular mechanisms of ageing of the stem cells responsible for regenerating blood cells and opens up a new avenue for reducing their progressive functional decline with age.

16 Oct 2015

Researchers identify triple mechanism that prevents onset of chromosomal instability

Universitat Autònoma de Barcelona researchers have identified for the first time the triple mechanism that stops chromosome separation in response to situations that compromise the integrity of the genetic information. The loss of this response capacity is characteristic of cancerous cells.

18 Sep 2015

Research: Spindle matrix protein supports assembly of spindle matrix, microtubules in cell-division process

Every high school biology class learns about the tiny cells that comprise our bodies, as well as about many of the diverse actions that they perform.

18 Sep 2015

Scientists discover new mechanism that protects brain stem cells against aging-induced damage

Neural stem cells generate new neurons throughout life in the mammalian brain. However, with advancing age the potential for regeneration in the brain dramatically declines.

18 Sep 2015

Studies using yeast genetics provide new insights into cell-division cycle

Studies using yeast genetics have provided new, fundamental insights into the cell-division cycle, researchers at the University of Michigan Life Sciences Institute report.

2 Sep 2015

WPI awarded NIH grant to explore ways to turn genetic tables against cancer

Taking aim at the fundamental biology of cancer cells, the National Institutes of Health has awarded $747,000 to Worcester Polytechnic Institute for a three-year research project to explore the molecular mechanisms associated with the genetic mutations and chromosome instability observed in all cancer cells.

7 Aug 2015

Understanding the workings of error correction mechanism in cell division

Cell biologists led by Thomas Maresca at the University of Massachusetts Amherst, with collaborators elsewhere, report an advance in understanding the workings of an error correction mechanism that helps cells detect and correct mistakes in cell division early enough to prevent chromosome mis-segregation and aneuploidy, that is, having too many or too few chromosomes.

30 Jul 2015

Study stresses importance of investigating telomeres to improve diagnoses, develop treatments for many diseases

Studying telomeres, the structures that protect the ends of chromosomes, has become a key issue in biology. In recent years, not only has their relation to ageing been confirmed; defective telomeres seem to be linked to more and more illnesses, including many types of cancer.

16 Jul 2015

Chromosomes play active role in animal cell division

Canadian and British researchers have discovered that chromosomes play an active role in animal cell division. This occurs at a precise stage - cytokinesis - when the cell splits into two new daughter cells.

14 Jul 2015

UCSF scientists identify characteristics of progenitor cells

University of California San Francisco scientists have identified characteristics of a family of daughter cells, called MPPs, which are the first to arise from stem cells within bone marrow that generate the entire blood system. The researchers said the discovery raises the possibility that, by manipulating the fates of MPPs or parent stem cells, medical researchers could one day help overcome imbalances and deficiencies that can arise in the blood system due to aging or in patients with specific types of leukemia.

19 Jun 2015

New research shows how human immune system could be manipulated to better fight disease

New research from Australian and Singaporean scientists has revealed how immune cell 'spies' are created, providing clues on how the immune system could be manipulated to better fight disease.

9 Jun 2015

New JIC research helps to settle important debate on epigenetic inheritance

New research findings by John Innes Centre scientists have helped to settle an important debate in the field of epigenetic inheritance. Using the flowering plant Arabidopsis thaliana as a model for their research, Professor Martin Howard, Professor Caroline Dean and members of their labs, have been trying to understand how organisms 'remember' past events at the cellular level.

4 Jun 2015

Genetically-programmed probiotics could help detect liver cancer metastases early-on

Scientists at the University of California, San Diego and the Massachusetts Institute of Technology have described a new method for detecting liver cancer metastases in mice. The approach uses over-the-counter probiotics genetically programmed to produce signals easily detectable in urine when liver cancer metastases are present.

2 Jun 2015

Secret to the life-long activity of a stem cell niche

The roots of a plant are constantly growing, so that they can provide the plant with water and minerals while also giving it a firm anchor in the ground. Responsible for these functions are pluripotent stem cells. In order to avoid differentiation and to remain pluripotent, these stem cells are dependent on signals from their neighbouring cells.

1 Jun 2015

Study reveals new molecular mechanism that helps protect genome from harmful effect of UV radiations

Researchers have uncovered a new molecular mechanism whereby human cells protect their genome from the detrimental effect of UV radiation and govern DNA replication in cellular mitosis, which, when it malfunctions, leads to harmful results.

29 May 2015

Overexpression of cyclin E protein could lead to breast cancer, leukemia

A new study led by scientists at The Scripps Research Institute sheds light on the cause of some cancers, including breast cancer and leukemia.

8 May 2015

New study shows ulcer-causing bacteria can directly interact with stomach stem cells

The ulcer-causing bacterium Helicobacter pylori can directly interact with stomach stem cells, causing the cells to divide more rapidly, according to a new study by researchers at the Stanford University School of Medicine.

7 May 2015

Max Planck Institute researchers find protein profiles of DNA repair

During each cell division, more than 3.3 billion base pairs of genomic DNA have to be duplicated and segregated accurately to daughter cells. But what happens when the DNA template is damaged in such a way that the replication machinery gets stuck? To answer this question, scientists in the team of Matthias Mann at the Max Planck Institute of Biochemistry in Martinsried near Munich, with colleagues in Copenhagen and at Harvard, have analyzed how the protein composition of the DNA replication machinery changes upon encountering damaged DNA.

5 May 2015

Daughter Cell News and Research

American scientists synthesize glycopolymers that prolong lifetime of healthy cells

Stem-cell scientists discover new view of how human blood is made

Study could help mitigate effects of ageing on blood stem cells, promote new therapies for anaemia

Researchers identify triple mechanism that prevents onset of chromosomal instability

Research: Spindle matrix protein supports assembly of spindle matrix, microtubules in cell-division process

Scientists discover new mechanism that protects brain stem cells against aging-induced damage

Studies using yeast genetics provide new insights into cell-division cycle

WPI awarded NIH grant to explore ways to turn genetic tables against cancer

Understanding the workings of error correction mechanism in cell division

Study stresses importance of investigating telomeres to improve diagnoses, develop treatments for many diseases

Chromosomes play active role in animal cell division

UCSF scientists identify characteristics of progenitor cells

New research shows how human immune system could be manipulated to better fight disease

New JIC research helps to settle important debate on epigenetic inheritance

Genetically-programmed probiotics could help detect liver cancer metastases early-on

Secret to the life-long activity of a stem cell niche

Study reveals new molecular mechanism that helps protect genome from harmful effect of UV radiations

Overexpression of cyclin E protein could lead to breast cancer, leukemia

New study shows ulcer-causing bacteria can directly interact with stomach stem cells

Max Planck Institute researchers find protein profiles of DNA repair

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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