Deep Brain Stimulation News and Research

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Deep brain stimulation (DBS) is a surgical procedure used to treat a variety of disabling neurological symptoms—most commonly the debilitating symptoms of Parkinson’s disease (PD), such as tremor, rigidity, stiffness, slowed movement, and walking problems. The procedure is also used to treat essential tremor, a common neurological movement disorder. At present, the procedure is used only for patients whose symptoms cannot be adequately controlled with medications.

Researcher launches new DBS clinical trial to pinpoint brain activity in depressed people

A top medical researcher at Barrow Neurological Institute at St. Joseph's Hospital in Phoenix, Arizona, has launched a clinical trial to pinpoint brain activity in depressed people by using scientifically designed sad and heartrending photos and music.

10 Mar 2011

First recording of cortically induced neural activity of basal ganglia in Parkinson's disease, dystonia during DBS

Movement disorders such as Parkinson's diseases and dystonia are caused by abnormal neural activity of the basal ganglia located deep in the brain. The basal ganglia are connected to the cerebral cortex in the brain surface through complex neural circuits.

10 Mar 2011

New study sheds 'light' on intricate brain cell connections responsible for anxiety

A new study sheds light--both literally and figuratively--on the intricate brain cell connections responsible for anxiety.

10 Mar 2011

Noninvasive MR-guided focused ultrasound successfully treats essential tremor

A new chapter in medical history opened days ago when noninvasive MR-guided focused ultrasound was used to successfully treat a patient with essential tremor (ET), a progressive neurological disorder that affects millions of people worldwide and causes involuntary shaking of the hands, head, face, eyelids, voice or other muscles.

10 Mar 2011

Brain implant surgery can improve life for people with cervical dystonia

Implanting electrodes into a pea-sized part of the brain can dramatically improve life for people with severe cervical dystonia - a rare but extremely debilitating condition that causes painful, twisting neck muscle spasms - according to the results of a pilot study led by Jill Ostrem, MD and Philip Starr, MD PhD at the University of California, San Francisco.

9 Mar 2011

fMRI reveals complexity of consciousness

Using a sophisticated imaging test to probe for higher-level cognitive functioning in severely brain-injured patients provides a window into consciousness -- but the view it presents is one that is blurred in fascinating ways, say researchers at Weill Cornell Medical College in the Feb. 25 online edition of the journal Brain.

25 Feb 2011

Scientists suggest that lateral habenula can be a prime locus of human depression

A team of neuroscientists at Cold Spring Harbor Laboratory, Brookhaven National Laboratory and UC San Diego has collected evidence suggesting that a previously overlooked portion of the brain could be a prime locus of human depression.

24 Feb 2011

Deep brain stimulation therapy promising against severe OCD

When obsessive-compulsive disorder is of crippling severity and drugs and behavior therapy can't help, there has been for just over a year a thread - or rather a wire - of hope. By inserting a thin electrode deep into the brain, doctors can precisely deliver an electrical current to a cord of the brain's wiring and soften the severity of the symptoms. "Deep brain stimulation" therapy for OCD won Food and Drug Administration approval in 2009 for extreme cases under its humanitarian device exemption.

19 Feb 2011

WINCS detects and measures serotonin levels in brain through deep brain stimulation

Mayo Clinic researchers have concluded that, through deep brain stimulation, a Wireless Instantaneous Neurotransmitter Concentration System (WINCS) can detect and measure serotonin levels in the brain. The findings suggest that in the future such measurements of serotonin may help establish a therapeutic mechanism of deep brain stimulation for psychiatric disease.

16 Feb 2011

New clinical trial to test surgery specifically for Type 2 diabetes

A new clinical trial at NewYork-Presbyterian Hospital/Weill Cornell Medical Center is among the first to test surgery specifically for Type 2 diabetes. The aim of the study is to understand whether surgery can control diabetes, as well or even better than the best medical treatment available today. This is the first study of its kind open to patients who are overweight or mildly obese.

14 Feb 2011

New trial tests surgery for Type 2 diabetes

11 Feb 2011

Full genetic blueprint of multiple prostate tumors laid bare

For the first time, researchers have laid bare the full genetic blueprint of multiple prostate tumors, uncovering alterations that have never before been detected and offering a deep view of the genetic missteps that underlie the disease. The study, made possible by key advances in whole genome sequencing and analysis, points to several new prostate cancer genes and a critical category of genomic changes as important drivers of prostate cancer growth.

10 Feb 2011

Law allowing use of unproven brain devices in "orphan" neuropsychiatric disorders needs to be strengthened: Experts

Warning that patients could be at risk, an interdisciplinary group of multinational investigators is calling on the U.S. Congress and federal regulators to tighten a law that permits use of brain devices to treat rare neuropsychiatric disorders without supporting clinical trials or stringent patient oversight.

7 Feb 2011

WINCS device can detect and measure serotonin levels in brain: Mayo Clinic

Mayo Clinic researchers have concluded that, through deep brain stimulation, a Wireless Instantaneous Neurotransmitter Concentration System can detect and measure serotonin levels in the brain. The findings suggest that in the future such measurements of serotonin may help establish a therapeutic mechanism of deep brain stimulation for psychiatric disease.

5 Feb 2011

More careful regulation of FDA's Humanitarian Device Exemption in psychiatric patients needed

4 Feb 2011

Physicians suggest new target structure for deep brain stimulation

Nearly ten percent of all cases of depression are so severe that the patients do not respond to any established treatment method. Targeted stimulation of areas in the brain using a type of "brain pacemaker" has recently raised hopes: According to initial studies, half of patients with the most severe depression treated in this manner see a significant improvement in mood.

31 Jan 2011

Patients with chronic depression can benefit from pioneering neurosurgical treatment

Pioneering neurosurgical treatment, a world first in Bristol, which very accurately targets brain networks involved in depression, could help people who suffer with severe and intractable depression.

25 Jan 2011

Researchers discover new treatment for difficult-to-control high blood pressure

Researchers were surprised to discover what may be a potential new treatment for difficult-to-control high blood pressure, according to a case report published in the January 25, 2011, print issue of Neurology, the medical journal of the American Academy of Neurology.

25 Jan 2011

St. Jude Medical's Athena programmer DBS system receives Australian TGA approval

St. Jude Medical, Inc., a global medical device company, today announced regulatory approval from the Australian Therapeutic Goods Administration (TGA) of its Athena™ programmer, a deep brain stimulation (DBS) therapy management system.

24 Jan 2011

Deep brain stimulation stabilizes motor symptoms in Parkinson's disease over time

Parkinson's disease symptoms begin subtly and worsen as damage to certain brain cells continues. But an electrical stimulation device implanted deep in the brain and programmed remotely, along with medications, may provide some control of "motor symptoms" common to the disease, such as shaking, stiffness, and loss of muscle control.

19 Jan 2011

Deep Brain Stimulation News and Research

Further Reading

Researcher launches new DBS clinical trial to pinpoint brain activity in depressed people

First recording of cortically induced neural activity of basal ganglia in Parkinson's disease, dystonia during DBS

New study sheds 'light' on intricate brain cell connections responsible for anxiety

Noninvasive MR-guided focused ultrasound successfully treats essential tremor

Brain implant surgery can improve life for people with cervical dystonia

fMRI reveals complexity of consciousness

Scientists suggest that lateral habenula can be a prime locus of human depression

Deep brain stimulation therapy promising against severe OCD

WINCS detects and measures serotonin levels in brain through deep brain stimulation

New clinical trial to test surgery specifically for Type 2 diabetes

New trial tests surgery for Type 2 diabetes

Full genetic blueprint of multiple prostate tumors laid bare

Law allowing use of unproven brain devices in "orphan" neuropsychiatric disorders needs to be strengthened: Experts

WINCS device can detect and measure serotonin levels in brain: Mayo Clinic

More careful regulation of FDA's Humanitarian Device Exemption in psychiatric patients needed

Physicians suggest new target structure for deep brain stimulation

Patients with chronic depression can benefit from pioneering neurosurgical treatment

Researchers discover new treatment for difficult-to-control high blood pressure

St. Jude Medical's Athena programmer DBS system receives Australian TGA approval

Deep brain stimulation stabilizes motor symptoms in Parkinson's disease over time

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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