Depressive Disorder News and Research

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Research study examines the depression rate in chronic kidney disease patients

One in five patients with chronic kidney disease is depressed, even before beginning long-term dialysis therapy or developing end-stage renal disease, UT Southwestern Medical Center researchers have found.

9 Sep 2009

Psychological therapy for breast cancer patients reduces blood inflammation levels

A psychological intervention for newly diagnosed breast cancer patients with symptoms of depression not only relieves patients' depression but also lowers indicators of inflammation in the blood.

1 Sep 2009

IntelGenx Technologies shareholder conference call to update shareholders on CPI-300

Horst G. Zerbe, President and CEO of IntelGenx Technologies Corp. ("IntelGenx") will be holding a shareholder conference call to update shareholders on the company's CPI-300 product and remark on related legal proceedings. The call will be held on Tuesday September 1, 2009 at 2.30 p.m. Eastern Standard Time.

31 Aug 2009

Decreased cravings for pleasure may be at root of a core symptom of major depressive disorder

Decreased motivation to seek and experience pleasurable experiences, known as anhedonia, is a primary symptom of major depressive disorder. Anhedonia is less responsive to many antidepressants and often persists after other symptoms of depression subside. However, understanding the different components of anhedonia - the desire to obtain something pleasurable versus experiencing pleasure - has been difficult for researchers to determine in humans.

12 Aug 2009

Depression among preschoolers - may continue into childhood

Depression among preschoolers appears to be a continuous, chronic condition rather than a transient developmental stage, according to a report in the August issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

4 Aug 2009

Major depressive disorder redefined

Researchers from Rhode Island Hospital's department of psychiatry propose that the definition for major depressive disorder (MDD) should be shortened to include only the mood and cognitive symptoms that have been part of the definition in the Diagnostic and Statistical Manual of Mental Disorders (DSM) for the past 35 years.

24 Jul 2009

Light therapy as a treatment for sexual dysfunctions

Although we are still far from knowing exactly where and how the pineal suppressive role is exerted, the fact that the gland exerts an inhibitory function on the reproductive axis is widely accepted. In fact, the pineal seems to exert its hormonal effect at different levels of the reproductive axis, both at the hypothalamic-pituitary level and at the gonadal level, where melatonin receptors have also been found.

9 Jun 2009

Lilly resubmits Cymbalta supplemental NDA for chronic pain to FDA

Eli Lilly and Company has resubmitted its supplemental New Drug Application (sNDA) for Cymbalta (duloxetine HCl) for the management of chronic pain to the U.S. Food and Drug Administration (FDA).

3 Jun 2009

Negative mood-related drinking may mean vulnerability for major depression and alcohol dependence

Major depression (MD) and alcohol dependence (AD) co-occur in individuals and within families at higher rates than expected by chance. This study looked at how mood-related drinking motives may explain the overlapping familial risk for MD and AD. Findings suggest that individuals with strong mood-related drinking motives, especially those based on negative feelings, may be vulnerable to developing both MD and AD.

12 May 2009

Participants in antidepressant drug trials are atypical patients

One reason antidepressant medication treatments do not work as well in real life as they do in clinical studies could be the limited type of study participants selected, researchers at UT Southwestern Medical Center have found.

12 May 2009

GSK to divest U.S. rights for Wellbutrin XL to Biovail

GlaxoSmithKline has announced that it has entered into an agreement to divest full commercial rights to Wellbutrin XL in the United States to Biovail International Laboratories SRL, a subsidiary of Biovail Corporation, for $510 million (euro 340 million). The agreement is subject to Hart-Scott-Rodino regulatory clearance in the United States.

6 May 2009

Aussies wanted for international groundbreaking study on depression

Australians researchers have put out a call for 400 people to take part in a study on depression.

26 Apr 2009

Seroquel XR supplemental NDA recommended for approval

The U.S. Food and Drug Administration (FDA) Psychopharmacologic Drugs Advisory Committee (PDAC) conducted a review of the safety and efficacy of supplemental new drug applications (sNDA) for Seroquel XR (quetiapine fumarate) extended-release tablets proposed for the treatment of major depressive disorder (MDD) and generalized anxiety disorder (GAD).

9 Apr 2009

FDA approves Symbyax for treatment-resistant depression

The U.S. Food and Drug Administration (FDA) has approved a new indication for Symbyax (olanzapine and fluoxetine HCl capsules), Eli Lilly and Company has announced.

23 Mar 2009

Groundbreaking study into depression

Medical researchers from Sydney University's Brain Dynamics Centre have launched a world-first study that could lead to a dramatic improvement in how people are treated medically for depression.

19 Mar 2009

Cephalon announces positive results from study of NUVIGIL in bipolar depression

Cephalon, Inc. has announced positive results from a phase two clinical trial of NUVIGIL(R) (armodafinil) Tablets [C-IV] as adjunctive therapy for treating major depressive disorder in adults with bipolar I disorder.

17 Mar 2009

Inexpensive depression screening tool works in resource poor countries

A study published in the February 2009 issue of the Journal of General Internal Medicine reports that a highly reliable depression screening tool known as the Patient Health Questionnaire-9 (PHQ-9) used across the United States and Europe can be effectively administered in resource poor Africa to HIV/AID patients, a population whose mental health needs have been underserved.

24 Feb 2009

Mum who tried to poison her children placed on good-behaviour bond

An Australian woman who tried to poison her two children last year has been placed on a good-behaviour bond after pleading guilty to the charge of intending to harm them.

10 Feb 2009

Boys have greater psychological well-being than girls

Self-concept may be defined as the totality of perceptions that each person has of themselves, and this self identity plays an important role in the psychological functioning of everyone.

3 Feb 2009

Physical self-concept and psychological well-being/unwellness during adolescence

Self-concept may be defined as the totality of perceptions that each person has of themselves, and this self identity plays an important role in the psychological functioning of everyone. To date, however, there has been no investigation into the relationship that physical self-concept has with psychological well-being or psychological unwellness.

3 Feb 2009