Depressive Disorder News and Research

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Mylan announces FDA approval for generic Effexor and tentative approval for generic antihypertensive Avalide

Mylan Inc. today announced that its subsidiary, Mylan Pharmaceuticals Inc., has received final approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for Venlafaxine Hydrochloride (HCl) Tablets 25 mg (base), 37.5 mg (base), 50 mg (base), 75 mg (base) and 100 mg (base).

16 Jun 2008

UT Southwestern investigators test groundbreaking depression research in real-world setting

UT Southwestern Medical Center psychiatry researchers have taken what they learned from their groundbreaking research on treating depression and are applying it to real-world clinical settings.

15 Jun 2008

Depression in seniors linked to low levels of vitamin D

Researchers in Holland have found that older people with low blood levels of vitamin D and high blood levels of the parathyroid hormone are more likely to be depressed.

6 May 2008

Study identifies problems with diagnosis of bipolar disorder

A new study by Rhode Island Hospital and Brown University researchers reports that fewer than half the patients previously diagnosed with bipolar disorder received a diagnosis of bipolar disorder based on a comprehensive, psychiatric diagnostic interview--the Structured Clinical Interview for DSM-IV (SCID).

6 May 2008

Low blood levels of vitamin D may be associated with depression in seniors

Older adults with low blood levels of vitamin D and high blood levels of a hormone secreted by the parathyroid glands may have a higher risk of depression, according to a report in the May issue of Archives of General Psychiatry.

5 May 2008

Results of St. Jude Medical deep brain stimulation study presented at APA meeting

St. Jude Medical, Inc. today announced pilot study results from the first multi-center study investigating deep brain stimulation (DBS) of Brodmann Area 25 for major depressive disorder.

5 May 2008

NIH study reveals incidence, precursors and psychiatric sequelae of major psychiatric disorders

A new study by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) presents results on the first onset of substance use disorders (i.e., alcohol and drug abuse and dependence) and major mood and anxiety disorders, based on Wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC).

22 Apr 2008

St. Jude Medical awarded U.S. patent for neurostimulation therapy for depression

St. Jude Medical, Inc. has announced it has been awarded a patent from the U.S. Patent and Trademark Office for treating depression using neurostimulation therapy in an area of the brain known as Brodmann Area 25.

21 Apr 2008

Link found between insomnia and depression in young adults

A study published in the April 1 issue of the journal SLEEP confirms the persistent nature of insomnia and the increased risk of subsequent depression among individuals with insomnia.

2 Apr 2008

When your antidepressants don't work

should you switch to a different medication from the same class or should you try an antidepressant medication that has a different mechanism of action?

26 Mar 2008

Does depression lead to stroke?

Psychological distress, but not depression, may increase the risk of stroke, according to a study published in the March 4, 2008, issue of Neurology, the medical journal of the American Academy of Neurology.

4 Mar 2008

FDA approves PRISTIQ for the treatment of adult patients with major depressive disorder

Wyeth Pharmaceuticals, a division of Wyeth, has announced that the U.S. Food and Drug Administration (FDA) has approved PRISTIQ (desvenlafaxine), a structurally novel, once-daily serotonin-norepinephrine reuptake inhibitor (SNRI), to treat adult patients with major depressive disorder (MDD).

3 Mar 2008

AstraZeneca submits sNDA for SEROQUEL XR for treatment of major depressive disorder

AstraZeneca has announced the submission of a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for once- daily SEROQUEL XR (quetiapine fumarate) Extended-Release Tablets to seek approval for the treatment of major depressive disorder (MDD) as monotherapy, adjunct therapy, and maintenance therapy in adult patients.

1 Mar 2008

Depressed teens respond well to combination therapy

More than half of teenagers with the most debilitating forms of depression that do not respond to treatment with selective serotonin reuptake inhibitors (SSRIs) show improvement after switching to a different medication combined with cognitive behavioral therapy, researchers at UT Southwestern Medical Center and their colleagues in a multicenter study have found

27 Feb 2008

Adding therapy helps adolescents with depression not responding to SSRIs

For adolescents with depression not responding to an initial treatment with a selective serotonin reuptake inhibitor (SSRI; a class of antidepressant drugs), switching medications and adding cognitive behavioral therapy resulted in an improvement in symptoms, compared to just changing medications, according to a study in the February 27 issue of JAMA: The Journal of the American Medical Association.

27 Feb 2008

Study suggests Risperidone long-acting injection combined with standard treatment helped delay time to relapse in patients with bipolar disorder

Patients with frequently relapsing bipolar disorder had a significant delay in the time to an initial relapse when risperidone long-acting injection (RLAI) was combined with standard treatment, according to a new study. The study compared patients who received RLAI and standard treatment to those who received standard treatment combined with placebo.

4 Feb 2008

Matters of the mind can affect matters of the heart

A new study by McGill University and Université de Montréal researchers has found that major anxiety and/or depression, can double a coronary artery disease patient's chances of repeated heart ailments.

21 Jan 2008

Study finds most psychiatric patients have more than one diagnosis

A new study by Rhode Island Hospital researchers reports that the majority of 2,300 psychiatry outpatients had more than one disorder when seeking treatment, and more than one-third had at least three disorders.

15 Jan 2008

Help with getting off the couch

It's only been a few weeks since you made that New Year's resolution to exercise more, but already you're finding reasons to skip days - maybe even weeks.

10 Jan 2008

AstraZeneca submits sNDAs for SEROQUEL XR for bipolar symptoms

AstraZeneca has announced that the company has submitted two separate supplemental New Drug Applications (sNDAs) to the U.S. Food and Drug Administration (FDA) for once-daily SEROQUEL XR (quetiapine fumarate) Extended-Release Tablets to seek approval for the treatment of manic episodes associated with bipolar disorder and the treatment of depressive episodes associated with bipolar disorder.

3 Jan 2008