Developmental Biology News and Research

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UCSC engineers develop new method to automate the growth of cerebral organoids

A team of engineers at UC Santa Cruz has developed a new method for remote automation of the growth of cerebral organoids – miniature, three-dimensional models of brain tissue grown from stem cells.

28 Nov 2022

Study uncovers new rules for lineage progression

The hypothalamus, one of the most complex brain regions in the mammalian nervous system, contains an astonishing heterogeneity of neurons that regulate endocrine, autonomic and behavioral functions. It not only regulates food consumption, water intake, body temperature, circadian rhythm and sleep to maintain the survival of individual organisms, but also controls puberty onset and reproductive behavior to sustain the breeding population.

17 Nov 2022

Research reveals new treatment avenue for pediatric high grade gliomas harboring a genetic mutation

Researchers at the University of Michigan Rogel Cancer Center have identified a novel treatment approach to an aggressive type of pediatric brain cancer, using therapies already approved to treat cancer.

16 Nov 2022

Researchers characterize subtle differences in the brains of primates and humans

While the physical differences between humans and non-human primates are quite distinct, a new study reveals their brains may be remarkably similar. And yet, the smallest changes may make big differences in developmental and psychiatric disorders.

9 Nov 2022

Huntington's disease impairs autophagy in older patients

Huntington's disease, a fatal, inherited neurodegenerative condition, is caused by a genetic error present at birth, though its symptoms often don't begin until middle adulthood.

28 Oct 2022

New studies point to a broadly applicable treatment for neurodegenerative diseases

Two new studies from Washington University School of Medicine in St. Louis support development of a broadly applicable treatment for neurodegenerative diseases that targets a molecule that serves as the central executioner in the death of axons, the wiring of the nervous system.

26 Oct 2022

Research proposes a set of conditions that could be the starting point for ulcerative colitis

Ulcerative colitis is the most common type of inflammatory bowel disease, characterised by chronic ulcers and inflammation in the colon and rectum.

18 Oct 2022

High-sugar diet lowers the ability of the taste system to sense sweetness

For many people, a high-sugar diet has become almost accidental. Three-quarters of food in the supermarket has added sugar, according to University of Michigan researcher Monica Dus, leading the scientist to wonder whether our sense of taste can become dulled to sweetness.

12 Oct 2022

Researchers receive $9 million grant to study how ‘jumping genes’ influence Alzheimer's disease

Scientists have identified a handful of gene mutations that cause or contribute to the onset of Alzheimer's disease.

11 Oct 2022

Thirdhand smoke exposure elevates biomarkers associated with the initiation of skin diseases

Thirdhand smoke, or THS, comprises the residual pollutants from tobacco smoke that remain on surfaces and in dust after tobacco has been smoked.

11 Oct 2022

Researchers take new approach to studying the development of the human brain

Researchers at ETH Zurich are growing human brain-like tissue from stem cells and are then mapping the cell types that occur in different brain regions and the genes that regulate their development.

7 Oct 2022

Researchers identify a new gene implicated in rare lysosomal storage disorder

In a rare disease called mucolipidosis type II, people’s hearts and abdomens swell, and their bones grow malformed.

6 Oct 2022

Obscure family of viruses already endemic in African monkeys "poised for spillover" to humans

An obscure family of viruses, already endemic in wild African primates and known to cause fatal Ebola-like symptoms in some monkeys, is "poised for spillover" to humans, according to new University of Colorado Boulder research published online Sept. 30 in the journal Cell.

30 Sep 2022

Oxytocin induces epicardial cell proliferation, study finds

The neurohormone oxytocin is well-known for promoting social bonds and generating pleasurable feelings, for example from art, exercise, or sex. But the hormone has many other functions, such as the regulation of lactation and uterine contractions in females, and the regulation of ejaculation, sperm transport, and testosterone production in males.

30 Sep 2022

Love hormone can activate heart repair mechanisms after cardiac injury, study finds

Researchers show for the first time that the neurohormone oxytocin has a previously unsuspected function in both zebrafish and human cell cultures: it stimulates mature cells in the epicardium of the heart to become stem-like cells, which can replace heart cells lost after damage.

30 Sep 2022

Study shows how a common epigenetic modification can be transmitted across multiple generations

Without altering the genetic code in the DNA, epigenetic modifications can change how genes are expressed, affecting an organism's health and development.

27 Sep 2022

Scientists track origins of group 3 and group 4 medulloblastoma to the rhombic lip

Scientists at St. Jude Children's Research Hospital have discovered which cells give rise to certain high-risk groups of medulloblastoma.

21 Sep 2022

Study identifies genetic variation linked with posterior urethral valves in males

Genetic variation affecting developmental genes not previously linked to urethral development may contribute to a congenital condition that is the most common cause of kidney failure in young males, a study published today in eLife suggests.

20 Sep 2022

JGU researchers seek to gain a better understanding of depression

Human beings and fruit flies have very little in common - at first sight. However, studying these flies it is in fact possible to find out more about human nature, particularly when it comes to depressive disorders.

16 Sep 2022

Study investigates the effect of vitamin D and fish oil on croup

Babies and children under three years old are less likely to develop croup if their mothers took fish oil and vitamin D supplements during pregnancy, according to new results from a clinical trial. The findings are from a randomised controlled trial – the 'gold standard' for medical research – that will be presented at the European Respiratory Society International Congress in Barcelona, Spain. It is the first large study of its kind to investigate the effects of vitamin D and fish oil on croup.

5 Sep 2022

Developmental Biology News and Research

UCSC engineers develop new method to automate the growth of cerebral organoids

Study uncovers new rules for lineage progression

Research reveals new treatment avenue for pediatric high grade gliomas harboring a genetic mutation

Researchers characterize subtle differences in the brains of primates and humans

Huntington's disease impairs autophagy in older patients

New studies point to a broadly applicable treatment for neurodegenerative diseases

Research proposes a set of conditions that could be the starting point for ulcerative colitis

High-sugar diet lowers the ability of the taste system to sense sweetness

Researchers receive $9 million grant to study how ‘jumping genes’ influence Alzheimer's disease

Thirdhand smoke exposure elevates biomarkers associated with the initiation of skin diseases

Researchers take new approach to studying the development of the human brain

Researchers identify a new gene implicated in rare lysosomal storage disorder

Obscure family of viruses already endemic in African monkeys "poised for spillover" to humans

Oxytocin induces epicardial cell proliferation, study finds

Love hormone can activate heart repair mechanisms after cardiac injury, study finds

Study shows how a common epigenetic modification can be transmitted across multiple generations

Scientists track origins of group 3 and group 4 medulloblastoma to the rhombic lip

Study identifies genetic variation linked with posterior urethral valves in males

JGU researchers seek to gain a better understanding of depression

Study investigates the effect of vitamin D and fish oil on croup

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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