Developmental Biology News and Research

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Scientists create new molecule that holds promise in fighting disease via gene therapy

Inherited diseases, as well as many cancers and cardiovascular diseases, may eventually be helped by this approach, which delivers therapeutic genes directly to cells. These genes can correct genetic defects, for example, or help the body's immune system fight cancer cells.

23 Mar 2006

Zoologists succeed for the first time in transforming stem cells in freshwater polyps

Stem cells are versatile all-rounders. In the medical field, high hopes are resting on these miracle workers. However, we still understand very little about them.

21 Mar 2006

Rapamycin (sirolimus) may be effective in treating kidney disease

A widely available drug may be effective in treating kidney disease, report scientists at the University of California, Santa Barbara. They describe the discovery in the online edition of the Proceedings of the National Academies of Science.

21 Mar 2006

Inhibiting gamma secretase may prevent amyloid plaque build-up thought to trigger Alzheimer's disease

Oregon Health & Science University is participating in a national study of a drug that may prevent Alzheimer's disease by blocking an enzyme that produces plaques believed to trigger the disorder.

21 Mar 2006

Yale researchers shed new light on the mechanism of nerve cell growth

Researchers at Yale shed new light on the mechanism of nerve cell growth by identifying novel functions for a molecular "motor" protein, myosin-II, according to an article in Nature Cell Biology.

20 Mar 2006

Newly identified biomarkers may help reverse the ageing process

Lotions and potions that promise to remove wrinkles and other effects of aging crowd cosmetics aisle shelves, but do these treatments really work?

7 Mar 2006

Researchers edge closer to cardiac tissue engineering

Researchers have developed a method to engineer blood vessels within the tissue of previously engineered heart muscle. Trials have resulted in significant improvement in heart function.

1 Mar 2006

Man-made heart tissue improves heart function

Researchers have developed a method to engineer blood vessels within the tissue of previously engineered heart muscle. Trials have resulted in significant improvement in heart function.

27 Feb 2006

Symposium on celiac disease

A scientific symposium on celiac disease, "Genetic and Immune Mechanisms in Celiac Disease," will be held at the University of California, San Diego (UCSD) School of Medicine on Friday, February 10, from 8:30 a.m. to 12 noon. The symposium, hosted by UCSD’s newly established William K. Warren Medical Research Center for Celiac Disease, will be held at the university’s Center for Molecular Genetics conference room.

23 Jan 2006

Researchers identify protein essential for the maintenance of synapses

Nerve cells store and transmit information via special contact sites called synapses. Synapses also play a role in determining what we remember and what we forget.

18 Jan 2006

Hedgehog protein plays a role in regulating fat and bone

A protein that guides the early development of creatures as diverse as fruit flies and humans also plays a role in regulating fat and bone formation in adult organisms, researchers at UT Southwestern Medical Center have discovered.

10 Jan 2006

Astrocytes play a direct role in controlling blood flow in the brain - influencing Alzheimer's

New findings that long-overlooked brain cells play an important role in regulating blood flow in the brain call into question one of the basic assumptions underlying today's most sophisticated brain imaging techniques and could open a new frontier when it comes to understanding Alzheimer's disease.

6 Jan 2006

Study finds two genes that are essential for the proper development of muscle

Scientists at the University of North Carolina at Chapel Hill have found two genes that are essential for the proper development of muscle.

30 Dec 2005

Study finds two genes that are essential for the proper development of muscle

Scientists at the University of North Carolina at Chapel Hill have found two genes that are essential for the proper development of muscle.

30 Dec 2005

Plant stem cell breakthrough made

Totipotent stem cells allow plants to build new organs throughout their whole life. But it has been unclear how hormones and genetic factors work together to prevent plants from having growth that is either stunted, or uncontrolled and tumor-like. Scientists from the Max Planck Institute for Developmental Biology have now uncovered a feedback mechanism, involving a growth-enhancing hormone and a regulatory protein, which controls the number of stem cells the plant produces.

22 Dec 2005

Researchers link microRNA - miR 196 - to limb development

A tiny strand of molecules plays a role in how our arms and legs develop and grow - a finding that sheds light on perplexing bits of material once dismissed as genetic "junk," say scientists at the University of Florida and Harvard University.

5 Dec 2005

Discovery of novel form of regulation of the GLI1 gene

The Quaking gene, first described as a mutation in mice that causes rapid tremor, is thought to suppress tumor formation and protect humans from cancer.

14 Nov 2005

Researchers determine how Tsg101 gene controls cellular growth

Researchers at Emory University School of Medicine and their colleagues have discovered a genetic mechanism that controls cellular growth in the fruit fly Drosophila melanogaster, and believe it likely that a similar system may be at work in normal and cancerous human cells.

1 Nov 2005

Method to count the absolute number of individual protein molecules inside a living cell

Yale researchers have reported a method to count the absolute number of individual protein molecules inside a living cell, and to measure accurately where they are located, two basic hurdles for studying biology quantitatively.

20 Oct 2005

Fear of falling gait

The patient came into the doctor's office in a wheelchair, weighted down by a diagnosis of Parkinson's disease, taking medication for the disorder and insisting she was unable to stand or walk. Thirty minutes later, after jogging down the hallway, she strolled out the door.

9 Oct 2005