Developmental Biology News and Research

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Cord blood transplantation now a viable option for adult leukemia patients

Stem cell transplantation using umbilical cord blood is a standard treatment option for blood disorders in children, but not for adults, due to the difficulty of obtaining a sufficiently large dose of cells.

20 Jan 2005

Protein in cardiac muscle cells may play a crucial role in heart failure prevention

Scientists at the University of North Carolina at Chapel Hill School of Medicine have shown that a protein in cardiac muscle cells may play a crucial role in heart failure prevention.

5 Jan 2005

Ubiquitination protects against improper Notch signaling

The Notch pathway is an important molecular signaling mechanism whose existence has been known, or at least hinted at, for nearly a century since the identification of a mutant strain of Drosophila fruit flies with "notched" wings in Thomas Hunt Morgan's lab in 1910.

28 Dec 2004

Significant advance in understanding the human genome

An Oregon Health & Science University-led development of a technique for identifying control elements that drive the expression of genes in brain cells could unleash the disease-fighting potential of the much-hailed human genome.

28 Dec 2004

Research advances understanding of urinary tract infections

Anyone who has ever had a urinary tract infection knows that they can be difficult to fight.

20 Nov 2004

Unusual protein pair that stops blood vessels' growth in the developing back

In experiments with mice, a research team led by Johns Hopkins scientists has discovered an unusual protein pair that stops blood vessels' growth in the developing back.

18 Nov 2004

Research provides more evidence of communication between developing nerves and blood vessels

In a developing embryo, the growth of nerves cannot outpace the establishment of life-giving blood vessels. Now, researchers have found that a protein intimately involved in blood vessel patterning actually belongs to a family of proteins known to guide neural development.

18 Nov 2004

Safe, effective and reversible alternative contraceptives for men

Most men know when their family is complete, and vasectomy remains the most effective and safest form of sterilization. Around 10% of vasectomized men in the U.S desire vasectomy reversal due to the high divorce rate in this country and other life circumstances.

16 Nov 2004

Novel enzyme in sperm is essential for spontaneous and independent movement

A study led by scientists at the University of North Carolina at Chapel Hill has found that a novel enzyme in sperm is essential for spontaneous and independent sperm movement as well as male fertility.

16 Nov 2004

Autophagy may even provide a clue to the mythical fountain of youth

The cells of higher organisms have an internal mechanism for chewing up and recycling parts of themselves, particularly in times of stress, like starvation and disease. But nobody is quite sure yet whether this recently discovered process protects cells, or causes damage.

5 Nov 2004

Scientists have found a fossil that explains the history of the nose

Our ancestors had two nostrils, one front and one back, but no opening on the palate or in the throat. They could smell, but not breathe with their nose. How did our nose evolve?

4 Nov 2004

Major step forward in understanding how the organs are placed in their correct positions in the body

Researchers at the Instituto Gulbenkian de Ciência (IGC), in Portugal, have taken a major step forward in understanding one of the fundamental questions in the field of developmental biology today: how the organs are placed in their correct positions in the body.

12 Oct 2004

Discovery of naturally occurring RNA "switches" that manage the amino acid glycine

Two University of Washington computer scientists are part of a team that has discovered a pair of rare, naturally occurring RNA "switches" in a class of bacteria that work cooperatively to manage the amino acid glycine.

11 Oct 2004

Marijuana use may increase the risk of ectopic (tubal) pregnancies

It is not known whether drugs that block or, in the case of marijuana, over-stimulate the CB1 receptor can cause ectopic pregnancy in humans. However, "our results raise caution for women of reproductive ages regarding the chronic use of marijuana for recreation or pain alleviation," the researchers concluded.

27 Sep 2004

Discovery of key molecular step which allows cancer cells to move to different parts of the body

Researchers at The University of Texas M. D. Anderson Cancer Center have figured out a key molecular step by which a cancer cell can unhook itself from the mesh weave of other cancer cells in a tumor, and move away to a different part of the body - the process, known as metastasis, that makes cancer so dangerous.

27 Sep 2004

Cancers, including colon, prostate, and leukemia, continue to grow unchecked

Many cancers, including colon, prostate, and leukemia, continue to grow unchecked because they do not respond to a signal to die and stop proliferating from Transforming Growth Factor-beta (TGF-b).

8 Sep 2004

Mouse stem cells may help restore hearing loss in humans

The work is important because, in humans, inner ear sensory hair cells are a precious commodity. Humans are born with only about sixteen thousand of these sound detectors in each ear, which can be easily damaged by age, certain illnesses, exposure to loud sounds, and some medications. Once damaged, the cells do not easily grow back. And with the cell loss comes so-called irreversible hearing loss.

26 Aug 2004

Stanford researchers identify leukemia stem cells

A handful of leukemia cells constantly replenish the supply of cancerous cells, according to new work by Stanford University School of Medicine researchers.

11 Aug 2004

New gene-silencing technique

A new gene-silencing technique that takes place in the nucleus of human cells, has been demonstrated by researchers at the University of California, San Diego (UCSD) School of Medicine and the VA San Diego Healthcare System.

5 Aug 2004

Adenosine triphosphate is a culprit in causing the devastating damage of spinal cord injury

ATP - adenosine triphosphate, the vital energy source that keeps our body’s cells alive, runs amok at the site of a spinal cord injury, pouring into the area around the wound and killing the cells that normally allow us to move, scientists report in the cover story of the August issue of Nature Medicine.

29 Jul 2004