Developmental Biology News and Research

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Optimized human small intestinal organoids can help better study the functioning of small intestines

Researchers from the Organoid group (formerly the Clevers group) have improved human small intestinal organoids – miniature versions of the small intestine.

24 Aug 2022

Study pinpoints a three-pronged approach that makes liver cancer cells stop growing

Liver cancer's rapid growth leads to a vulnerability in its energy-production and cell-building processes that may be potently exploited with a new combination-treatment strategy, according to a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

3 Aug 2022

Newly developed bioadhesive ultrasound helps in long-term continuous imaging of diverse organs

A wearable ultrasound device attached using a durable, adhesive, stretchy material enables continuous medical imaging of internal organs and tissues for patients on the go, researchers report. They tested their patch in real people doing activities like jogging and drinking fluids.

29 Jul 2022

Bacterial species known for causing diarrheal infections may also drive colorectal cancer

Data collected by researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy suggest that Clostridioides difficile, or C. diff, a bacterial species well known for causing serious diarrheal infections, may also drive colorectal cancer.

14 Jul 2022

Researchers challenge centuries-old beliefs about limb regeneration

Ken Muneoka is no stranger to disrupting the field of regeneration; for example, in a 2019 ground-breaking publication in Nature, the Texas A&M University College of Veterinary Medicine & Biomedical Sciences professor proved for the first time that joint regeneration in mammals was possible.

6 Jul 2022

Rapid test can identify which variant has infected a COVID-19 patient in just a few hours

In just a few hours, UT Southwestern scientists can tell which variant has infected a COVID-19 patient – a critical task that can potentially influence treatment decisions but takes days or weeks at most medical centers.

30 Jun 2022

Study focuses on how telomerase activity affects the regenerative potential of stem cells in human urine

The Wake Forest Institute for Regenerative Medicine researchers who were the first to identify that stem cells in human urine have potential for tissue regenerative effects, continue their investigation into the power of these cells.

28 Jun 2022

New study looks at the role of beta cells in triggering autoimmunity

Research into the causes of type 1 diabetes often focuses on the autoimmune response, where the immune system destroys pancreatic islet beta cells that produce insulin.

28 Jun 2022

Maternal vaccination during pregnancy helps protect babies from being hospitalized due to COVID-19

In a new study sponsored by the Centers for Disease Control and Prevention and published in the New England Journal of Medicine, researchers provide additional evidence that COVID-19 vaccination during pregnancy helps protect babies younger than 6 months from being hospitalized due to COVID-19.

24 Jun 2022

Scientists identify new genetic disease that delays children's intellectual development

Scientists have identified a new genetic disease, which causes some children's brains to develop abnormally, resulting in delayed intellectual development.

24 Jun 2022

U-M researchers reveal how a mutated protein acts as risk factor in Parkinson’s disease

In about a fifth of the cases of Parkinson’s disease, look to a small, malfunctioning protein in the lysosome as a risk factor, say University of Michigan researchers.

23 Jun 2022

Study offers recommendations for improving statistical inference in population genomics

The second century Alexandrian astronomer and mathematician Claudius Ptolemy had a grand ambition. Hoping to make sense of the motion of stars and the paths of planets, he published a magisterial treatise on the subject, known as the Almagest.

6 Jun 2022

New findings reveal potential mechanisms for cellular defects in human laminopathies

A Northwestern Medicine study has uncovered distinct roles for major nuclear lamin isoforms in maintaining intracellular interactions and cellular mechanics, according to findings published in the Proceedings of the National Academy of Sciences.

1 Jun 2022

Aging does not influence liver renewal, research shows

The liver has a unique ability to regenerate after damage. However, it was unknown whether this ability decreases as we age.

31 May 2022

Exposure to traffic-related air pollutants linked with pregnancy complications

A new study in mice by UCLA scientists reveals how exposure to traffic-related air pollutants causes cellular changes in the placenta that can lead to pregnancy complications and affect the health of both mother and offspring.

31 May 2022

SARS-CoV-2 infection during late pregnancy can lead to severe inflammatory responses in the placenta

SARS-CoV-2 infections of women in late pregnancy frequently spread to their placentas and led to inflammation, according to a study from investigators at Weill Cornell Medicine and NewYork-Presbyterian.

31 May 2022

IOB's new scRNA-seq protocol provides a snapshot of the cell transcriptome at unprecedented resolution

Single-cell RNA-sequencing (scRNA-seq) shows which genes are turned on in a cell and what their level of transcription is. This allows in-depth assessment of the biology of individual cells, and detection of changes that may indicate disease.

31 May 2022

Immune response and the lymphatic system are key to cardiac repair after heart attack

Immune response and the lymphatic system are central to cardiac repair after a heart attack, according to a study from Ann & Robert H. Lurie Children's Hospital of Chicago and Northwestern University Feinberg Cardiovascular Research Institute.

25 May 2022

Mitosis in moss plants could be far more similar to animal cell division than previously thought

For a new plant to grow from a seed, cells need to divide numerous times. Daughter cells can each take on different tasks and sometimes vary in size. How plants determine the plane of cell division in this process, known as mitosis, is being researched by Prof. Dr. Ralf Reski and Dr. Elena Kozgunova from the University of Freiburg in a joint effort with Prof. Dr. Gohta Goshima from Nagoya University.

6 May 2022

Elevated BMI may exacerbate abnormalities associated with aging sperm cells

Single-cell analysis of autopsied human testes suggests that abnormalities associated with aging sperm cells might be exacerbated by elevated body mass index (BMI).

2 May 2022

Developmental Biology News and Research

Optimized human small intestinal organoids can help better study the functioning of small intestines

Study pinpoints a three-pronged approach that makes liver cancer cells stop growing

Newly developed bioadhesive ultrasound helps in long-term continuous imaging of diverse organs

Bacterial species known for causing diarrheal infections may also drive colorectal cancer

Researchers challenge centuries-old beliefs about limb regeneration

Rapid test can identify which variant has infected a COVID-19 patient in just a few hours

Study focuses on how telomerase activity affects the regenerative potential of stem cells in human urine

New study looks at the role of beta cells in triggering autoimmunity

Maternal vaccination during pregnancy helps protect babies from being hospitalized due to COVID-19

Scientists identify new genetic disease that delays children's intellectual development

U-M researchers reveal how a mutated protein acts as risk factor in Parkinson’s disease

Study offers recommendations for improving statistical inference in population genomics

New findings reveal potential mechanisms for cellular defects in human laminopathies

Aging does not influence liver renewal, research shows

Exposure to traffic-related air pollutants linked with pregnancy complications

SARS-CoV-2 infection during late pregnancy can lead to severe inflammatory responses in the placenta

IOB's new scRNA-seq protocol provides a snapshot of the cell transcriptome at unprecedented resolution

Immune response and the lymphatic system are key to cardiac repair after heart attack

Mitosis in moss plants could be far more similar to animal cell division than previously thought

Elevated BMI may exacerbate abnormalities associated with aging sperm cells

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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