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$Clinical trial shows preliminary efficacy of all-oral regimen for patients with lenalidomide-refractory multiple myeloma$

Clinical trial shows preliminary efficacy of all-oral regimen for patients with lenalidomide-refractory multiple myeloma

Early results from an Alliance for Clinical Trials in Oncology randomized clinical trial of adults with multiple myeloma relapsing on frontline lenalidomide therapy showed that adding ixazomib (Ninlaro®) to pomalidomide and dexamethasone as part of second line therapy extended the length of time patients lived before their disease worsened (progression-free survival) compared with patients who received pomalidomide and dexamethasone.

21 Dec 2021

Humanized mice reveals why few COVID-19 cases are more severe than others

Why do 80 to 90% of people infected with COVID-19 experience only mild cases while 10 to 20% face more severe or life-threatening symptoms?

20 Dec 2021

A nematode infection can become severe and deadly with the use of corticosteroids

Healthcare workers in tropical and sub-tropical settings where strongyloidiasis is prevalent or caring for patients who have travelled to such areas, need to maintain a high level of awareness about the use of corticosteroids, including when this class of anti-inflammatories is given to patients suspected of infection with SARS-CoV-2.

19 Dec 2021

Hyperbaric oxygen treatment quickly resolves severe breathing difficulties in COVID-19 patients

High pressure (hyperbaric) oxygen resolves severe breathing difficulties in COVID-19 patients much more quickly than standard therapy, taking an average of 3 rather than 9 days, reveal the results of a small comparative clinical trial published online in Emergency Medicine Journal.

15 Dec 2021

Dexamethasone News and Research

Clinical trial shows preliminary efficacy of all-oral regimen for patients with lenalidomide-refractory multiple myeloma

Humanized mice reveals why few COVID-19 cases are more severe than others

A nematode infection can become severe and deadly with the use of corticosteroids

Hyperbaric oxygen treatment quickly resolves severe breathing difficulties in COVID-19 patients

Thousands of the UK’s most vulnerable people to receive cutting-edge COVID-19 treatments at home

A case of post-vaccination MIS in an adult without prior SARS-CoV-2 infection

£700 million will help hospitals across England tackle waiting lists and improve care

Can dexamethasone reduce prolonged COVID-19 symptoms?

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Model simulations show no need for DEX dose adjustments in COVID-19 patients with liver disease

£375 million Government funding to improve treatment for neurodegenerative diseases

What are the anti-COVID drugs currently in development?

Identification of long COVID patients using big data

UK government announces deals to secure two new COVID-19 treatments

Dispensing of hydroxychloroquine and ivermectin in Australia jumped in first year of COVID

Scientists describe SARS-CoV-2 uptake in tissue-resident human macrophages enhanced by virus-specific antibodies

Neurokinin-1 receptor: a potential drug target for the treatment of COVID-19

Thousands of vulnerable hospital patients set to benefit from new COVID-19 treatment

Pregnancy complications with COVID-19

Implications of persistent SARS-CoV-2 infection in patients with lymphoid malignancies

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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